NR 572 Exam 1 | 2026/2027 Chamberlain Advanced Acute Care Management | Actual Exam Verified Answers with Detailed Rationales | Grade A| AGACNP & Critical Care Prep | Downloadable PDF

INSTANT PDF DOWNLOAD — This is the comprehensive Exam 1 preparation guide for NR 572 - Advanced Acute Care Management (2026/2027) at Chamberlain University, featuring actual exam verified answers with detailed rationales. Designed for Adult-Gerontology Acute Care Nurse Practitioner (AGACNP) students, this resource consolidates the essential acute and critical care management concepts required to master the NR 572 Exam and excel in advanced acute care practice. The guide is meticulously aligned with Chamberlain University curriculum, AACN AGACNP certification blueprints, and current evidence-based acute care standards. This verified resource provides comprehensive coverage of key NR 572 Advanced Acute Care Management exam topics, including: Shock Syndromes (hypovolemic shock—causes (hemorrhage (trauma, surgery, GI bleed, ruptured aneurysm, ruptured ectopic pregnancy, postpartum hemorrhage), burns (fluid shifts, third spacing), dehydration (vomiting, diarrhea, NG suctioning, diuresis, diabetic ketoacidosis (DKA), hyperglycemic hyperosmolar state (HHS), adrenal insufficiency, diabetes insipidus (DI), heat stroke, excessive sweating, inadequate intake), pancreatitis (third spacing), bowel obstruction (third spacing), ascites (cirrhosis, heart failure, malignancy), pleural effusion, peritonitis), pathophysiology (decreased intravascular volume → decreased preload → decreased stroke volume → decreased cardiac output → decreased tissue perfusion → cellular hypoxia → anaerobic metabolism → lactic acidosis → organ dysfunction → multiple organ dysfunction syndrome (MODS) → death), stages (compensated (tachycardia, cool extremities, delayed capillary refill, narrow pulse pressure, mild hypotension (may be normal), oliguria, anxiety, confusion, thirst, dry mucous membranes, decreased skin turgor), decompensated (hypotension (systolic BP 90 mm Hg or drop 40 mm Hg from baseline), tachycardia (120 bpm), tachypnea, weak thready pulse, cyanosis, anuria, altered mental status (lethargy, obtundation, coma), cold clammy skin, mottling, absent peripheral pulses, metabolic acidosis, elevated lactate), irreversible (refractory hypotension despite aggressive fluid resuscitation and vasopressors, anuria, severe lactic acidosis (lactate 10 mmol/L), multi-organ failure (acute kidney injury (AKI), acute respiratory distress syndrome (ARDS), disseminated intravascular coagulation (DIC), acute liver failure, myocardial depression, cerebral ischemia, bowel ischemia, sepsis, death)), hemodynamic parameters (CVP (central venous pressure) low (5 mm Hg), PAOP (pulmonary artery occlusion pressure, wedge pressure) low (8 mm Hg), CO (cardiac output) low, SVR (systemic vascular resistance) high, SvO2 (mixed venous oxygen saturation) low (60%), ScvO2 (central venous oxygen saturation) low (70%)), management (airway (supplemental oxygen, intubation for respiratory failure, hypoxemia, altered mental status, impending airway compromise), breathing (assist with ventilation if needed, target SpO2 92-94%, PaO2 60-80 mm Hg, avoid hyperoxia (FiO2 0.60, PaO2 150 mm Hg) → oxygen toxicity, absorption atelectasis, increased ROS), circulation (IV access (two large bore (16-18 gauge) peripheral IVs, central line if peripheral access inadequate, intraosseous (IO) if unable to obtain IV access emergently), fluid resuscitation (isotonic crystalloids (0.9% normal saline (NS), lactated Ringer's (LR), Plasma-Lyte), initial bolus 1-2 L (20-30 mL/kg) over 15-30 minutes, reassess, repeat as needed (up to 4-6 L), avoid 0.45% NS (hypotonic), avoid dextrose (D5W, D5 1/2 NS) (distributes out of vascular space, worsens hyponatremia, hyperglycemia), blood products (packed red blood cells (PRBCs) for hemorrhagic shock (target Hgb 7-8 g/dL, higher threshold 9-10 g/dL for acute coronary syndrome (ACS), active bleeding, hemodynamic instability, elderly, septic shock? controversial, restrictive strategy (transfuse when Hgb 7) non-inferior to liberal strategy (Hgb 9-10) in septic shock (TRISS trial, TRICS trial), for hemorrhagic shock (massive transfusion protocol (MTP) for active hemorrhage, ratio 1:1:1 (PRBCs:FFP:platelets), fresh frozen plasma (FFP) (coagulopathy, PT/PTT 1.5x normal, fibrinogen 100-150 mg/dL, replace with FFP or cryoprecipitate (fibrinogen)), platelets (50,000 with active bleeding, 20,000 with no bleeding, 10,000 for prophylaxis, transfusion threshold higher for neurosurgery, trauma, intracranial hemorrhage, active bleeding), cryoprecipitate (fibrinogen 100-150 mg/dL, also contains factor VIII, XIII, von Willebrand factor (vWF), fibronectin, treat hypofibrinogenemia, DIC, massive transfusion, cardiac surgery, obstetrical hemorrhage, fibrinogen concentrate (RiaSTAP) alternative to cryoprecipitate, fewer infectious risk, no thawing, faster administration, more consistent fibrinogen content), tranexamic acid (TXA) (antifibrinolytic, 1 g IV over 10 minutes, then 1 g IV over 8 hours, for trauma patients within 3 hours of injury (CRASH-2 trial), for postpartum hemorrhage (WOMAN trial), for GI bleeding (HALT-IT trial, no benefit, increased VTE risk), for intracerebral hemorrhage (ICH) (TICH-2 trial, no benefit), for subarachnoid hemorrhage (SAH) (ULTRA trial, no benefit), for cardiac surgery (ATACAS trial, no benefit, increased seizures), for orthopedic surgery (decreases blood loss, transfusion, no increase in VTE), for prostatectomy, hysterectomy, cesarean section