NURS 5334 Advanced Pharmacology Test 1 | Practice Questions & Answers with Detailed Rationales

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NURS 5334 Advanced Pharmacology Test 1 | Practice Questions & Answers with Detailed Rationales

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2025/2026

Institution NURS 5334

Course NURS 5334

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Comprehensive test bank for NURS 5334 Advanced Pharmacology Test 1 Includes high-quality practice questions with accurate answers and detailed rationales Covers key pharmacology topics, drug mechanisms, side effects, and clinical applications Designed to strengthen critical thinking and improve exam performance Ideal for nursing students preparing for advanced pharmacology exams Perfect for revision, quizzes, and test preparation

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Nurss5334-AdvancedsPharm-Tests1

Pregnancy:sChangessinsdrugsmetabolisms-sCORRECTsANSWER✔-
HepaticsmetabolismsandsGFRsincreasesduringspregnancy,sdosagessofssome
sdrugssmaysneedstosbesincreaseds

-Forssomesdrugs,shepaticsmetabolismsincreasessduringspregnancy--
>ssomesdrugssmaysneedstosbesincreased
-
Tonesandsmotilitysofsthesbowelsdecreasesinspregnancy,scausingsintestinalstr
ansitstimestosincrease
-->morestimesforsdrugsstosbesabsorbed-->smightsneedstosreducesdosage
-Prolongationsofsdrugseffectsstotals1-2slifesincreases

Fetalsdevelopmentsinspregnancys(stages)s-sCORRECTsANSWER✔-
preimplantation/presomite:sconception-2sweeks:sallsorsnothings
-embryonicsperiod:sweekss3-8:sgrosssmalformations
-Fetalsperiod:sweeks9-sterm:sexposuresdisruptssfunctionsnotsgrosssanatomy

PregnancysLabelings-sCORRECTsANSWER✔-
Assofs2015,sthesFoodsandsDrugsAdministrationshadsasPregnancysandsLactat
ionsLabelingsRuleschange.
-
Nosmoresletteringsofsthescategoriessofsdrugssforspregnancy.sAccordingstosth
esletteringssystem,sdrugsscansbesputsintosonesofsfivesriskscategories:sbesA,sB
,sC,sD,sandsX.
-Bys2020,sallsprescriptionssmustsremovesletteringslabelssaltogether.

,-ThesPLLRsrequiressthreessectionssforslabeling:
os(1)spregnancy,s(2)slactation,sands(3)sfemalessandsmalessofsreproductivesp
otential.

Howsdosyousdecreasesrisksinsthesinfantsduringsbreastfeeding?s-
sCORRECTsANSWER✔osTakesthesdrugssimmediately saftersbreastfeedin

g
osAvoidsdrugssthatshaveslongshalf-lives
osChoosesdrugssthatstendstosbesexcludedsfromsmilk,sandsthatsaresleastslikelys
tosaffectsthesinfant
osAvoidsthesdrugssthatsaresknownstosbeshazardous
osUsestheslowestseffectivesdosagesforsthesshortestspossiblestime
osAbandonsplansstosbreastfeedsifsasnecessarysdrugsissknownstosbesharmfulst
ostheschild.

Howsdospediatricspatientssdiffersinstheirsresponsestosmedication?
sAbsorption? s-sCORRECTsANSWER✔osOralsadministration

-Gastricsemptyingstimesissprolongeds&sirregularsinsearlysinfancy
·sAdultsfunctionsats5-8smonths
·sForsdrugssthatsaresabsorbedsprimarilysfromsthesstomach,sdelayedsgastricse
mptyingsenhancessabsorption
·sForsdrugssthatsaresabsorbedsprimarilysfromsthesintestine,sabsorptionsissdel
ayed
·sBecausesgastricsemptyingstimesissirregular,sthespreciseseffectsonsabsorptio
nsissnotspredictable
-sGastricsAcidity

,·sVeryslows24shourssaftersbirth
·sDoessnotsreachsadultsvaluessfors2syears
·sLowsaciditysabsorptionsofsacid-labilesdrugssissincreased
osIntramuscular
-Slow,serraticsinsneonates
-
sDelayedsabsorption sassasresultsofslowsbloodsflowsduringsthesfirstsfewsdayss

ofslife
-
sBysearlysinfancy,sabsorption sofsIMsdrugssissmoresrapidsthansinsneonatessan

dsadults
osSkin
-sMoresrapidsandscompletesinsinfantssthansinsolderschildrensandsadults
-
sThesstratumscorneumsofsthesinfant'ssskinsissverysthin,sandsbloodsflowstosthes

skinsissgreatersinsinfantssthansinsolderspatients.sBecausesofsthissenhancedsab
sorption,sinfantssaresatsincreasedsrisksforstoxicitysfromstopicalsdrugs.

Howsdospediatricspatientssdiffersinstheirsresponsestosmedication?
sDistribution sr/tsproteinsbinding?s-sCORRECTsANSWER✔-

Bindingsofsdrugsstosalbuminsandsothersplasmasproteinssisslimitedsinsthesinfa
nt
-sAmountsofsserumsalbuminsissrelativelyslow
-
sEndogenousscompoundss(fatty sacids,sbilirubin)scompeteswithsdrugssforsav

ailablesbindingssites

, -sLimitedsdrug/proteinsbindingsinsinfantss--
>sconcentrationsofsfreeslevelssofsdrugssthatsusuallysundergosextensivesprote
insbindingsinsadultssissrelativelyshighsinsthesinfants-->sintensifiedseffects
-sReducedsdosagesneeded
-sAdultsproteinsbindingscapacitysbys10-12smonthssofsage

Howsdospediatricspatientssdiffersinstheirsresponsestosmedication?
sDistribution sr/tsBBB?s-sCORRECTsANSWER✔-

sNotsfullysdevelopedsatsbirth

-sDrugssandsotherschemicalsshavesrelativelyseasysaccessstosthesCNS
-sInfantssaresespeciallyssensitivestosdrugssthatsaffectsCNSsfunction
-
sallsmedicines semployedsforstheirsCNSseffectss(e.g.,smorphine,sphenobarbit

al)sshouldsbesgivensinsreducedsdosage
-
sDosagesshouldsalsosbesreducedsforsdrugssusedsforsactionssoutsidesthesCNSs

ifsthosesdrugssarescapablesofsproducingsCNSstoxicitysassassideseffect

Howsdospediatricspatientssdiffersinstheirsresponsestosmedication?
sMetabolismsr/tsHepaticsfunction?s-sCORRECTsANSWER✔osThesdrug-

metabolizingscapacitysofsnewbornssisslow
osNeonatessaresespeciallyssensitivestosdrugssthatsareseliminatedsprimarilysb
yshepaticsmetabolism
osThesliver'sscapacitystosmetabolizesmanysdrugssincreasedsrapidlysabouts1s
monthsaftersbirth
osThesabilitystosmetabolizesdrugssatsthesadultslevelsissreachedsasfewsmonthss
later

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Uploaded on: April 6, 2026
Number of pages: 55
Written in: 2025/2026
Type: Exam (elaborations)
Contains: Questions & answers

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