BIOCHEMISTRY AT RUTGERS EXAM 2
REVIEW Questions and Answers
1. In the following figure, which bond would be unable to
rotate? A
B
C
D
None of these choices
Answer B (the bond close to the double bond)
2. At pH 3, how many charged groups are present in the penta peptide
Ala-Asp-His-Ser-Lys
1
2
3
4
5
Answer 4
3. In chymotrypsin, only three amino acids are involved in catalysis, but
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,there are almost 200 amino acids in the entire protein. What is
the function of the other amino acids?
Build the scaffold of the active site
stabilize the 3D structure of the active site
build the scaffold of potential regulatory sites
serve all these functions
None of the above
Answer The remaining amino acids serve all of these functions.
4. Proteins such as
hemoglobin are known as proteins since binding of
a molecule to one site alters binding to other sites.
Ligand- activated
allosteric
induced -fit
cooperative
none of the above
Answer allosteric
5. While proteins are usually composed of linear chains of amino acids,
branched chains of amino acids and internally cross-linked chains can be found
in certain proteins. Polypeptide chains are most commonly linked to each other
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,through
hydrogen bonds
glycosidic bonds
peptide bonds
disulfide bonds
ester linkages
Answer disulfide bonds
6. Which of the following tripeptides would be expected to be the most
hy- drophobic?
KYG
DYG
DYA
KYA GYA
Answer
GYA
7. The predominant non-covalent interaction seen in
alpha-helices and beta-sheets is .
electrostatic interactions
hydrogen bonds
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, dipole-dipole interaction
hydrophobic interactions
all of the above
Answer hydrogen bonds
8. The side chain
of serine could interact with the side chain of using a(n) .
Val; hydrophobic interaction
His; hydrogen bond
Gln; hydrophobic interaction
Asn; electrostatic interaction
none of the above
Answer His; hydrogen bond
9. Myoglobin is ; hemoglobin is .
monomeric;
dimeric dimeric;
trimeric
monomeric;
trimeric dimeric;
tetrameric
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REVIEW Questions and Answers
1. In the following figure, which bond would be unable to
rotate? A
B
C
D
None of these choices
Answer B (the bond close to the double bond)
2. At pH 3, how many charged groups are present in the penta peptide
Ala-Asp-His-Ser-Lys
1
2
3
4
5
Answer 4
3. In chymotrypsin, only three amino acids are involved in catalysis, but
1/
52
,there are almost 200 amino acids in the entire protein. What is
the function of the other amino acids?
Build the scaffold of the active site
stabilize the 3D structure of the active site
build the scaffold of potential regulatory sites
serve all these functions
None of the above
Answer The remaining amino acids serve all of these functions.
4. Proteins such as
hemoglobin are known as proteins since binding of
a molecule to one site alters binding to other sites.
Ligand- activated
allosteric
induced -fit
cooperative
none of the above
Answer allosteric
5. While proteins are usually composed of linear chains of amino acids,
branched chains of amino acids and internally cross-linked chains can be found
in certain proteins. Polypeptide chains are most commonly linked to each other
2/
52
,through
hydrogen bonds
glycosidic bonds
peptide bonds
disulfide bonds
ester linkages
Answer disulfide bonds
6. Which of the following tripeptides would be expected to be the most
hy- drophobic?
KYG
DYG
DYA
KYA GYA
Answer
GYA
7. The predominant non-covalent interaction seen in
alpha-helices and beta-sheets is .
electrostatic interactions
hydrogen bonds
3/
52
, dipole-dipole interaction
hydrophobic interactions
all of the above
Answer hydrogen bonds
8. The side chain
of serine could interact with the side chain of using a(n) .
Val; hydrophobic interaction
His; hydrogen bond
Gln; hydrophobic interaction
Asn; electrostatic interaction
none of the above
Answer His; hydrogen bond
9. Myoglobin is ; hemoglobin is .
monomeric;
dimeric dimeric;
trimeric
monomeric;
trimeric dimeric;
tetrameric
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52
