NR565 Advanced Pharmacology Final
Exam
What is the primary mechanism of action of methimazole in
treating hyperthyroidism?
(a) Inhibiting the synthesis of thyroid hormones
(b) Increasing the storage of thyroid hormones
(c) Enhancing the release of thyroid hormones
(d) Directly destroying overactive thyroid cells
Explanation
Methimazole inhibits thyroid peroxidase, reducing the synthesis of
T3 and T4 hormones.
Question 2
What side effect is NOT typically associated with radioactive iodine
therapy?
(a) Neck tenderness
(b) Swollen salivary glands
(c) Dry mouth
(d) Hair loss
Explanation
Common side effects include neck tenderness, dry mouth, and taste
changes. Hair loss is not typically associated.
Question 3
Why is radioactive iodine therapy recommended for some female
clients planning to become pregnant?
(a) To destroy overactive thyroid cells before pregnancy
(b) To accelerate fertility after radiation therapy
(c) To prevent thyroid cancer during pregnancy
1
,NR565 Advanced Pharmacology Final
Exam
(d) To enhance thyroid hormone production during pregnancy
Explanation
Radioactive iodine therapy is NOT recommended for women who
are pregnant. It is recommended for women who are planning to
become pregnant.
Question 4
How long does it typically take for methimazole to have a
meaningful effect on thyroid hormone levels?
(a) 3 to 12 weeks
(b) B 1 to 2 weeks
(c) Immediately upon administration
(d) 24 to 48 hours
Explanation
Methimazole requires 3 to 12 weeks to significantly impact thyroid
hormone levels because it does not affect existing hormone stores.
Question 5
What is the primary goal of thyroid disease management?
(a) Elevate blood pressure and induce anxiety
(b) Increase TSH levels and promote weight gain
(c) Suppress the immune system and cause bone loss
(d) Normalize thyroid hormone levels, control symptoms, and
prevent complications
Explanation
The primary goal is to normalize thyroid hormone levels, control
symptoms, and prevent complications.
2
, NR565 Advanced Pharmacology Final
Exam
Question 6
Why should levothyroxine be taken on an empty stomach?
(a) To reduce the risk of heartburn
(b) To prevent gastric ulcers
(c) To enhance absorption
(d) To increase appetite
Explanation
Taking levothyroxine on an empty stomach enhances its absorption.
Question 7
What is the function of levothyroxine?
(a) To provide synthetic thyroxine (T4) that converts into
triiodothyronine (T3)
(b) To block the conversion of T3 into T4
(c) To directly stimulate the thyroid gland to produce more
hormones
(d) To suppress the production of thyroid-stimulating hormone (TSH)
Explanation
Levothyroxine provides synthetic T4, which converts to T3, the
active thyroid hormone.
Question 8
Why is monitoring bone density important for clients on
levothyroxine?
(a) Because of the risk of accelerated bone loss
(b) Because it helps regulate blood sugar levels
(c) Because it prevents the development of kidney stones
3
Exam
What is the primary mechanism of action of methimazole in
treating hyperthyroidism?
(a) Inhibiting the synthesis of thyroid hormones
(b) Increasing the storage of thyroid hormones
(c) Enhancing the release of thyroid hormones
(d) Directly destroying overactive thyroid cells
Explanation
Methimazole inhibits thyroid peroxidase, reducing the synthesis of
T3 and T4 hormones.
Question 2
What side effect is NOT typically associated with radioactive iodine
therapy?
(a) Neck tenderness
(b) Swollen salivary glands
(c) Dry mouth
(d) Hair loss
Explanation
Common side effects include neck tenderness, dry mouth, and taste
changes. Hair loss is not typically associated.
Question 3
Why is radioactive iodine therapy recommended for some female
clients planning to become pregnant?
(a) To destroy overactive thyroid cells before pregnancy
(b) To accelerate fertility after radiation therapy
(c) To prevent thyroid cancer during pregnancy
1
,NR565 Advanced Pharmacology Final
Exam
(d) To enhance thyroid hormone production during pregnancy
Explanation
Radioactive iodine therapy is NOT recommended for women who
are pregnant. It is recommended for women who are planning to
become pregnant.
Question 4
How long does it typically take for methimazole to have a
meaningful effect on thyroid hormone levels?
(a) 3 to 12 weeks
(b) B 1 to 2 weeks
(c) Immediately upon administration
(d) 24 to 48 hours
Explanation
Methimazole requires 3 to 12 weeks to significantly impact thyroid
hormone levels because it does not affect existing hormone stores.
Question 5
What is the primary goal of thyroid disease management?
(a) Elevate blood pressure and induce anxiety
(b) Increase TSH levels and promote weight gain
(c) Suppress the immune system and cause bone loss
(d) Normalize thyroid hormone levels, control symptoms, and
prevent complications
Explanation
The primary goal is to normalize thyroid hormone levels, control
symptoms, and prevent complications.
2
, NR565 Advanced Pharmacology Final
Exam
Question 6
Why should levothyroxine be taken on an empty stomach?
(a) To reduce the risk of heartburn
(b) To prevent gastric ulcers
(c) To enhance absorption
(d) To increase appetite
Explanation
Taking levothyroxine on an empty stomach enhances its absorption.
Question 7
What is the function of levothyroxine?
(a) To provide synthetic thyroxine (T4) that converts into
triiodothyronine (T3)
(b) To block the conversion of T3 into T4
(c) To directly stimulate the thyroid gland to produce more
hormones
(d) To suppress the production of thyroid-stimulating hormone (TSH)
Explanation
Levothyroxine provides synthetic T4, which converts to T3, the
active thyroid hormone.
Question 8
Why is monitoring bone density important for clients on
levothyroxine?
(a) Because of the risk of accelerated bone loss
(b) Because it helps regulate blood sugar levels
(c) Because it prevents the development of kidney stones
3
