5upharmacologyuquizzesuATI
Auprovideruprescribesuphenobarbitaluforupt.uwhouhasuseizureudisorder.uTheu
med.uhasuaulonguhalf-
lifeuofu4udays.uHowumanyutimesuperudayushouldunurseuexpectutougiveuthisum
ed?
u
A)u1
B)u2
C)u3
D)u4u-uCORRECTuANSWER✔*Answer:uA*
Rationale:
A)uMedsuwithulonguhalf-
livesuremainuatutheirutherapeuticulevelsubetweenudosesuforulonguperiodsuofut
ime.uExpectutougiveuphenobarbitaluonceuauday.
B)uAumedutheunurseugivesu2xuaudayuwoulduhaveuaushorteruhalfulife.uAnuexa
mpleuisuvancomycin.
C)u3xuaudayuwoulduhaveushorteruhalf-life.uExampleuisuzidovudine.
D)u4xuaudayuwoulduhaveushortuhalf-life.uExampleuisuibuprofen.
Austaffueducatoruisureviewingumedicationudisagesuandufactorsuthatuinfluenc
eumedicationumetabolismuwithuaugroupuofunursesuatuanuin-
,serviceupresentation.uWhichuofutheufollowingufactorsushouldutheueducatorui
ncludeuasuaureasonutouadministerulowerumedudosages?
u(Selectualluthatuapply.)
A)uIncreasedurenaluexcretion
B)uIncreasedumed-metabolizinguenzymes
C)uLiverufailure
D)uPeripheraluvascularudisease
E)uConcurrentuuseuofumedicationutheusameupathwayumetabolizes.u-
uCORRECTuANSWER✔*Answer:uC,uE*
Rationale:
-
uLiverufailureudecreasesumetabolism uanduthusuincreaseduconcentration uofua
umedication. uThisurequiresudecreasingutheudosage.
-
uWhenusameupathwatumetabolizesutwoumeds,utheyucompeteuforumetabolis
m,utherebyuincreasingutheuconcentrationuofuoneuorubothumeds.uThisurequire
sudecreasingudosageuofuoneuorubothumeds.
-uIncreasedurenaluexcretionuanduincreasedumed-
metabolizinguenzymesudecreasesuconcentrationuofumed,usouyouuneedutouin
creaseutheumedudosage.
-
uPeripheral uvascularudiseaseuimpairsudistribution,usouiturequiresuincreasedu
dosage.
, Aunurseuisupreparingutouadministerueyeudropsutouaupt.uWhichuactionsushould
unurseutake?u(Selectualluthatuapply.)
A)uHaveuptulieuonuheruside.
B)uAskupt.utpulookuupuatuceiling.
C)uTellupt.utoublinkuwhenudropsuenteruherueye.
D)uDropumeduintoutheucenteruofupts.uconjunctivalusac.
E)uInstructupt.utoucloseuherueyeugentlyuafteruinstillation.u-
uCORRECTuANSWER✔*Answer:uB,uD,uE*
Rationale:
-
uPt.ushoulduloopuupwardutoukeepudropsufromufollinguontouherucornea.uShoul
dudropumeduinucenteruofuconjunctivalusacutoupromoteudistribution.uShoulduc
loseuherueyeugentlyutoupromoteudistributionuofumed.u
-
uPt.ushouldusituoruinuausupineupositionutoufacilitateuinstillationuofueyeudrops.u
ShoulduNOTublinkusousheudoesntuejectueyeudrops.uIfusheudoesublink,ushould
urepeatuinstillation.
Nurseuisucompletingudischargeuteachinguforupt.uwhouhasuaunewuprescriptio
nuforutransdermalupatches.uWhichustatementsushouldunurseuidentifyuasuanui
ndicationuthatutheupt.uunderstandsutheuinstructions?
A)u"IuwillucleanutheusiteuwithuanualcoholuswabubeforeuIuapplyutheupatch."
B)u"Iuwillurotateutheuapplicationusitesuweekly."