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1. The characteristic, localized cardinal signs of acute inflammation include:
A) fever.
B) fatigue.
C) redness.
D) granuloma.
2. The vascular, hemodynamic stage of acute inflammation is initiated by momentary vasoconstriction
followed by vasodilation that causes localized:
A) bleeding.
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B) congestion.
C) pale skin.
D) coolness.
3. The cellular stage of acute inflammation is marked by the movement of leukocytes into
the area. Which of the following cells arrives early in great numbers?
A) Basophils
B) Lymphocytes
C) Neutrophils
D) Platelets
4. The phagocytosis process involves three distinct steps. What is the initial step in the
process?
A) Engulfment
B) Intracellular killing
C) Antigen margination
D) Recognition and adherence
5. Which of the following mediators of inflammation causes increased capillary permeability
and pain?
A) Serotonin
B) Histamine
C) Bradykinin
D) Nitric oxide
6. Inflammatory exudates are a combination of several types. Which of the following
exudates is composed of enmeshed necrotic cells?
A) Serous
B) Fibrinous
C) Suppurative
D) Membranous
7. The acute-phase systemic response usually begins within hours of the onset of
inflammation and includes:
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A) fever and lethargy.
B) decreased C-reactive protein.
C) positive nitrogen balance.
D) low erythrocyte sedimentation rate.
8. In contrast to acute inflammation, chronic inflammation is characterized by which of the
following phenomena?
A) Profuse fibrinous exudation
B) A shift to the left of granulocytes
C) Metabolic and respiratory alkalosis
D) Lymphocytosis and activated macrophages
9. Exogenous pyrogens (interleukin-1) and the presence of bacteria in the blood lead to the
release of endogenous pyrogens that:
A) stabilize thermal control in the brain.
B) produce leukocytosis and anorexia.
C) block viral replication in cells.
D) inhibit prostaglandin release.
10 An older adult patient has just sheared the skin on her elbow while attempted . to boost herself up in
bed, an event that has precipitated acute
inflammation in the region surrounding the wound. Which of the following events will
occur during the vascular stage of the patients inflammation?
A) Outpouring of exudate into interstitial spaces
B) Chemotaxis
C) Accumulation of leukocytes along the epithelium
D) Phagocytosis of cellular debris
11 Which of the following individuals most likely has the highest risk of . experiencing
chronic inflammation?
A) A patient who has recently been diagnosed with type 2 diabetes
B) A patient who is a carrier of an antibiotic-resistant organism
C) A patient who is taking oral antibiotics for an upper respiratory infection
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D) A patient who is morbidly obese and who has a sedentary lifestyle
12 Which of the following core body temperatures is within normal range? .
A) 35.9C (96.6F)
B) 38.0C (100.4F)
C) 35.5C (95.9F)
D) 37.3C (99.1F)
13 A postsurgical patient who is recovering in the postanesthetic recovery unit . states that she is
freezing cold. Which of the following measures is likely to be initiated in the patients hypothalamus in
an effort to reduce heat loss?
A) Opening of arteriovenous (AV) shunts
B) Reduced exhalation of warmed air
C) Contraction of pilomotor muscles
D) Decreased urine production
14 An elderly patient is dressed only in a hospital gown and complains of a
. draft in her room. Consequently, she has requested a warm blanket while she sits in her
wheelchair. Which of the following mechanisms of heat loss is most likely the
primary cause of her request?
A) Evaporation and conduction
B) Radiation and convection
C) Conduction and convection
D) Convection and evaporation
15 Which of the following pathophysiologic processes are capable of inducing . the production
of pyrogens? Select all that apply.
A) Acute inflammation
B) Obesity
C) Myocardial infarction
D) Malignancy
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1. The characteristic, localized cardinal signs of acute inflammation include:
A) fever.
B) fatigue.
C) redness.
D) granuloma.
2. The vascular, hemodynamic stage of acute inflammation is initiated by momentary vasoconstriction
followed by vasodilation that causes localized:
A) bleeding.
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,Advanced
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Physiology & Pathophysiology (2nd Ed, ISBN 9780826167552) – Full
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B) congestion.
C) pale skin.
D) coolness.
3. The cellular stage of acute inflammation is marked by the movement of leukocytes into
the area. Which of the following cells arrives early in great numbers?
A) Basophils
B) Lymphocytes
C) Neutrophils
D) Platelets
4. The phagocytosis process involves three distinct steps. What is the initial step in the
process?
A) Engulfment
B) Intracellular killing
C) Antigen margination
D) Recognition and adherence
5. Which of the following mediators of inflammation causes increased capillary permeability
and pain?
A) Serotonin
B) Histamine
C) Bradykinin
D) Nitric oxide
6. Inflammatory exudates are a combination of several types. Which of the following
exudates is composed of enmeshed necrotic cells?
A) Serous
B) Fibrinous
C) Suppurative
D) Membranous
7. The acute-phase systemic response usually begins within hours of the onset of
inflammation and includes:
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Physiology & Pathophysiology (2nd Ed, ISBN 9780826167552) – Full
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A) fever and lethargy.
B) decreased C-reactive protein.
C) positive nitrogen balance.
D) low erythrocyte sedimentation rate.
8. In contrast to acute inflammation, chronic inflammation is characterized by which of the
following phenomena?
A) Profuse fibrinous exudation
B) A shift to the left of granulocytes
C) Metabolic and respiratory alkalosis
D) Lymphocytosis and activated macrophages
9. Exogenous pyrogens (interleukin-1) and the presence of bacteria in the blood lead to the
release of endogenous pyrogens that:
A) stabilize thermal control in the brain.
B) produce leukocytosis and anorexia.
C) block viral replication in cells.
D) inhibit prostaglandin release.
10 An older adult patient has just sheared the skin on her elbow while attempted . to boost herself up in
bed, an event that has precipitated acute
inflammation in the region surrounding the wound. Which of the following events will
occur during the vascular stage of the patients inflammation?
A) Outpouring of exudate into interstitial spaces
B) Chemotaxis
C) Accumulation of leukocytes along the epithelium
D) Phagocytosis of cellular debris
11 Which of the following individuals most likely has the highest risk of . experiencing
chronic inflammation?
A) A patient who has recently been diagnosed with type 2 diabetes
B) A patient who is a carrier of an antibiotic-resistant organism
C) A patient who is taking oral antibiotics for an upper respiratory infection
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Physiology & Pathophysiology (2nd Ed, ISBN 9780826167552) – Full
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D) A patient who is morbidly obese and who has a sedentary lifestyle
12 Which of the following core body temperatures is within normal range? .
A) 35.9C (96.6F)
B) 38.0C (100.4F)
C) 35.5C (95.9F)
D) 37.3C (99.1F)
13 A postsurgical patient who is recovering in the postanesthetic recovery unit . states that she is
freezing cold. Which of the following measures is likely to be initiated in the patients hypothalamus in
an effort to reduce heat loss?
A) Opening of arteriovenous (AV) shunts
B) Reduced exhalation of warmed air
C) Contraction of pilomotor muscles
D) Decreased urine production
14 An elderly patient is dressed only in a hospital gown and complains of a
. draft in her room. Consequently, she has requested a warm blanket while she sits in her
wheelchair. Which of the following mechanisms of heat loss is most likely the
primary cause of her request?
A) Evaporation and conduction
B) Radiation and convection
C) Conduction and convection
D) Convection and evaporation
15 Which of the following pathophysiologic processes are capable of inducing . the production
of pyrogens? Select all that apply.
A) Acute inflammation
B) Obesity
C) Myocardial infarction
D) Malignancy
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