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PCB 4233 Immunology Exam 1 Questions With Correct Answers

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PCB 4233 Immunology Exam 1 Questions With Correct Answers

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PCB 4233 Immunology Exam 1 Questions
With Correct Answers


immune system 4 functions - CORRECT ANSWER✔✔--distinguish between self
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and altered self
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-distinguish between self and foreign invaders
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-promote mutualistic microorganism interactions
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-distinguish between foreign pathogens
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fluMIST - CORRECT ANSWER✔✔-attentuated virus
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-not good for immunocompromised people
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intramuscular influenza vaccination - CORRECT ANSWER✔✔-inactivated virus
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Dr. Ron Fouchier - CORRECT ANSWER✔✔-used ferrets as model to test
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mechanisms regulating infectivity/pathogenicity - how to build a better influenza
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-restricted from publish - bioterrorism
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Hemagglutinin - CORRECT ANSWER✔✔-One of the enzymes found on the surface
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of the Influenza virus; allows virus to fuse into the cell it is infecting
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,Neuraminidase - CORRECT ANSWER✔✔-One of the enzymes found on the | | | | | | | | | |


surface of the Influenza virus; allows virus to exit infected cell which promotes
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the release of progeny viruses from infected cells (infectivity)
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Thucydides - CORRECT ANSWER✔✔-430 BC noted that those who had recovered
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from plague could nurse the sick without repeat contraction of disease; first to
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come up with idea of immunis, meaning exempt
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variolation - CORRECT ANSWER✔✔-an early method of vaccination using infected
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material from a patient
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-15th century Turks and Chinese took dried crusts from smallpox pustules and
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inhaled/inserted into cuts of skin | | | |




Ed Jenner - CORRECT ANSWER✔✔-1798 - noted that milk maids who developed
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cowpox (milder disease) were immune to smallpox
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-inoculated 8 y/o with cowpox and infected with smallpox
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Pustules - CORRECT ANSWER✔✔-contain puss, immune cell, and attenuated virus
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-- resembles virus
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Smallpox - CORRECT ANSWER✔✔-A highly contagious viral disease characterized
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by fluid filled blisters on skin, scarring, blindness, and limb deformities
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-humans are the reservoir for the virus (unique to humans)
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-completely eradicated (vaccination is stronger than virus encountered in nature)
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-Variola major (30% death) or Variola minor (1%)
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, attenuated vaccine - CORRECT ANSWER✔✔-vaccine composed of a weakened
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form of the pathogen that is generally unable to cause disease
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-Louis Pasteur |




mumps - CORRECT ANSWER✔✔-contagious viral disease that leads to painful
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swelling of the salivary glands
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-most common in age 2-12 if not vaccinated
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-12-24 day incubation period
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MMR vaccine - CORRECT ANSWER✔✔-protects against measles, mumps, and
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rubella; should be given to children 12-15 m/o and again between age 4-6 or 11-
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12 if not former
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herd immunity - CORRECT ANSWER✔✔-works by decreasing the number of
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individuals who can harbor and spread an infectious agent; significantly
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decreasing the chances that susceptible individuals will become infected
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George Snell |




Jean Dausset
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Baruj Benacerraf - CORRECT ANSWER✔✔-researched MHC
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Susumu Tonegawa - CORRECT ANSWER✔✔-researched gene rearrangement in
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antibody production |




Peter Doherty
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