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Immunology PCB 4233 Exam 1 Questions With Correct Answers

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Immunology PCB 4233 Exam 1 Questions With Correct Answers

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Immunology PCB 4233 Exam 1 Questions
With Correct Answers

1. C3b :
| |




a. is chemotactic
| |




b. is an anaphylatoxin
| | |




c. opsonizes bacteria
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d. directly injures bacteria
| | |




e. is the inactive form of C3 - CORRECT ANSWER✔✔-c. opsonizes bacteria
| | | | | | | | | | |




A term generally used to describe all white blood cells is:
| | | | | | | | | |




a. Mast cell
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b. myeloid progenitor
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c. dendritic cell
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d. leukocyte
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e. polymorphonuclear (PMN) - CORRECT ANSWER✔✔-d. leukocyte
| | | | | |




What is the name given to the earliest intracellular vesicle that contains material
| | | | | | | | | | | | |


opsonized by macrophages? | |

,a. Opsonome
|




b. Membrane-attack complex
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c. Phagosome
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d. Lysosome
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e. Specific granules - CORRECT ANSWER✔✔-c. Phagosome
| | | | | |




The early events of inflammation are characterized by all of the following except
| | | | | | | | | | | | |


_____________:


a. Vasodilation
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b. Extravasation
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c. Pain
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d. Apoptosis
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e. Chemotaxis - CORRECT ANSWER✔✔-d. Apoptosis
| | | | |




All of the following are involved in the alternative pathway of complement
| | | | | | | | | | | |


activation except ________ | |




a. C4
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b. Factor B
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c. Factor D
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d. Properdin
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e. C5 - CORRECT ANSWER✔✔-a. C4
| | | | |

,A(n) _____________ is an inactive form of an enzyme that frequently participate
| | | | | | | | | | | |


in a cascade of enzymatic reactions during complement activation.
| | | | | | | |




a. Regulator of complement activation
| | | |




b. Convertase
|




c. Zymogen
|




d. Complement control protein module
| | | |




e. Opsonin - CORRECT ANSWER✔✔-c. Zymogen
| | | | |




Which of the following statements regarding TLR4 is false?
| | | | | | | |




a. The ligand for TLR4 is LPS
| | | | | |




b. TLR4 homo-dimerized upon binding with its ligand
| | | | | | |




c. TLR4 has an intracellular TIR domain
| | | | | |




d. TLR4 is an example of a phagocytic receptor
| | | | | | | |




e. The extracellular domain of TLR4 associate with MD2 - CORRECT ANSWER✔✔-
| | | | | | | | | | |


d. TLR4 is an example of a phagocytic receptor
| | | | | | | |




An antimicrobial peptide that protects epithelial surfaces from pathogens is:
| | | | | | | | |




a. Glycoprotein
|




b. Defensin
|




c. Proteoglycan
|




d. Lysozyme
|

, e. Sebum - CORRECT ANSWER✔✔-b. Defensin
| | | | |




Which of the following describes chemokines?
| | | | |




a. Membrane receptors that detect the presence of cytokines
| | | | | | | |




b. Soluble proteins that attract specific cells to an area
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c. Transcription factors that induce the expression of genes involved in cell
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adhesion
d. Adhesion molecules that bind to the inside of blood vessels
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e. PAMPs found on microorganisms particularly bacteria - CORRECT ANSWER✔✔-
| | | | | | | | |


b. Soluble proteins that attract specific cells to an area
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Which of the following is the correct relationship? _________ on _________
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recognize _________ on _________.
| | |




a. PRRs : macrophages; PAMPs : neutrophils
| | | | | | |




b. PRRs : pathogen; PAMPs : macrophages
| | | | | |




c. PAMPs : macrophages; PRRs : pathogens
| | | | | |




d. PAMPs : neutrophils; PRRs : pathogen
| | | | | |




e. PRRs : Macrophages; PAMPs : Pathogens - CORRECT ANSWER✔✔-e. PRRs :
| | | | | | | | | | | |


Macrophages; PAMPs : Pathogens | | |




Which of the following statement regarding the innate immune response is false:
| | | | | | | | | | |

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