NR 507 Dermatological Conditions: Psoriasis, Rosacea & Acne 2026
|Chamberlain
1. Which of the following is the primary pathophysiological mechanism in
psoriasis?
A. Hyperkeratosis and rapid turnover of keratinocytes
B. Bacterial infection of the dermal layer
C. Decrease in melanin production
D. Hypersensitivity to topical fungal organisms
Answer: A
Rationale: Psoriasis is characterized by shortened keratinocyte cell cycles, leading to
hyperproliferation and scales.
2. Which immune cells are primarily responsible for the inflammatory cascade in
psoriasis?
A. B-cells
B. Eosinophils
C. Basophils
D. T-cells
Answer: D
Rationale: Psoriasis is a T-cell mediated autoimmune inflammatory disease.
,3. A patient presents with silvery scales on an erythematous base on the
elbows. What is the likely diagnosis?
A. Rosacea
B. Acne Vulgaris
C. Psoriasis
D. Atopic Dermatitis
Answer: C
Rationale: Silvery scales on an erythematous base are classic signs of plaque psoriasis.
4. The Koebner phenomenon in psoriasis refers to:
A. The development of oily skin before an outbreak
B. The clearing of the center of a plaque
C. Bleeding when a scale is removed
D. The spreading of lesions after scratching or injury
Answer: D
Rationale: The Koebner phenomenon is the development of skin lesions in areas of
trauma.
5. What is the term for the pinpoint bleeding that occurs when a psoriasis scale
is removed?
A. Auspitz sign
B. Nikolsky sign
C. Hutchinson sign
D. Darier sign
Answer: A
Rationale: Auspitz sign is classic for psoriasis due to dilated capillaries under the thin
epithelium.
, 6. Which type of psoriasis is often triggered by a streptococcal throat infection?
A. Guttate psoriasis
B. Inverse psoriasis
C. Pustular psoriasis
D. Erythrodermic psoriasis
Answer: A
Rationale: Guttate psoriasis often appears as small drop-like lesions following a strep
infection.
7. Where is inverse psoriasis typically found?
A. Extensor surfaces like knees
B. The lower shins
C. The bridge of the nose
D. Skin folds and axillae
Answer: D
Rationale: Inverse psoriasis occurs in intertriginous areas such as the axilla or groin.
8. Psoriatic arthritis is estimated to affect what percentage of patients with
psoriasis?
A. 30%
B. 5-10%
C. 50-70%
D. Less than 1%
Answer: A
Rationale: Approximately 30% of patients with psoriasis develop inflammatory arthritis.
|Chamberlain
1. Which of the following is the primary pathophysiological mechanism in
psoriasis?
A. Hyperkeratosis and rapid turnover of keratinocytes
B. Bacterial infection of the dermal layer
C. Decrease in melanin production
D. Hypersensitivity to topical fungal organisms
Answer: A
Rationale: Psoriasis is characterized by shortened keratinocyte cell cycles, leading to
hyperproliferation and scales.
2. Which immune cells are primarily responsible for the inflammatory cascade in
psoriasis?
A. B-cells
B. Eosinophils
C. Basophils
D. T-cells
Answer: D
Rationale: Psoriasis is a T-cell mediated autoimmune inflammatory disease.
,3. A patient presents with silvery scales on an erythematous base on the
elbows. What is the likely diagnosis?
A. Rosacea
B. Acne Vulgaris
C. Psoriasis
D. Atopic Dermatitis
Answer: C
Rationale: Silvery scales on an erythematous base are classic signs of plaque psoriasis.
4. The Koebner phenomenon in psoriasis refers to:
A. The development of oily skin before an outbreak
B. The clearing of the center of a plaque
C. Bleeding when a scale is removed
D. The spreading of lesions after scratching or injury
Answer: D
Rationale: The Koebner phenomenon is the development of skin lesions in areas of
trauma.
5. What is the term for the pinpoint bleeding that occurs when a psoriasis scale
is removed?
A. Auspitz sign
B. Nikolsky sign
C. Hutchinson sign
D. Darier sign
Answer: A
Rationale: Auspitz sign is classic for psoriasis due to dilated capillaries under the thin
epithelium.
, 6. Which type of psoriasis is often triggered by a streptococcal throat infection?
A. Guttate psoriasis
B. Inverse psoriasis
C. Pustular psoriasis
D. Erythrodermic psoriasis
Answer: A
Rationale: Guttate psoriasis often appears as small drop-like lesions following a strep
infection.
7. Where is inverse psoriasis typically found?
A. Extensor surfaces like knees
B. The lower shins
C. The bridge of the nose
D. Skin folds and axillae
Answer: D
Rationale: Inverse psoriasis occurs in intertriginous areas such as the axilla or groin.
8. Psoriatic arthritis is estimated to affect what percentage of patients with
psoriasis?
A. 30%
B. 5-10%
C. 50-70%
D. Less than 1%
Answer: A
Rationale: Approximately 30% of patients with psoriasis develop inflammatory arthritis.
