FNP-BC 2026 Practice Exam (NGN-style questions) LATEST 2026
UPDATE FAST REVIWED FROM ACTUAL TEST 150 QUESTIONS
AND 100% VERIFIED ANSWERS| A+ GRADE Q&A | INSTANT
DOWNLOAD PDF
1. A 45-year-old patient presents with a persistent cough, fever, and malaise
for 3 weeks. Chest X-ray shows a localized infiltrate in the right lower lobe.
Which is the most likely diagnosis?
A. Community-acquired pneumonia
B. Pulmonary embolism
C. Asthma exacerbation
D. Acute bronchitis
Explanation: Community-acquired pneumonia commonly presents with
fever, productive cough, and localized infiltrates on imaging.
2. Which of the following vaccines is recommended annually for all adults?
A. Tdap
B. Influenza
C. MMR
D. Varicella
Explanation: Influenza vaccine is recommended yearly for all adults to
prevent seasonal flu.
3. A patient with type 2 diabetes reports polyuria, polydipsia, and unexplained
weight loss. Which lab test is most appropriate to confirm diagnosis?
A. Fasting lipid panel
B. Liver function test
C. Hemoglobin A1c
D. Urinalysis
Explanation: Hemoglobin A1c reflects average blood glucose levels over 2–
3 months and is diagnostic for diabetes.
4. Which antihypertensive class is first-line for a patient with chronic kidney
disease?
, A. Calcium channel blockers
B. Beta-blockers
C. ACE inhibitors
D. Diuretics
Explanation: ACE inhibitors slow progression of kidney disease and are
preferred for patients with proteinuria.
5. A 60-year-old patient presents with fatigue, pallor, and spoon-shaped nails.
Lab shows low hemoglobin and microcytosis. What is the most likely cause?
A. Vitamin B12 deficiency
B. Iron deficiency anemia
C. Hemolytic anemia
D. Aplastic anemia
Explanation: Microcytic anemia with pallor and spoon-shaped nails is
characteristic of iron deficiency.
6. A patient on warfarin presents with INR 5.5 and no bleeding. What is the
appropriate next step?
A. Continue warfarin
B. Hold warfarin and monitor INR
C. Administer vitamin B12
D. Start heparin
Explanation: An INR above 5 without bleeding warrants temporary
cessation and close monitoring.
7. Which of the following is the first-line treatment for acute otitis media in
children?
A. Amoxicillin
B. Azithromycin
C. Ciprofloxacin
D. Doxycycline
Explanation: Amoxicillin is first-line unless there is allergy or resistance.
8. A 28-year-old female reports dysuria, frequency, and urgency. Urinalysis
shows leukocyte esterase and nitrites. Which is the most likely diagnosis?
, A. Pyelonephritis
B. Uncomplicated urinary tract infection
C. Interstitial cystitis
D. Kidney stones
Explanation: Dysuria with positive nitrites and leukocyte esterase
indicates a bacterial UTI.
9. For a patient with chronic asthma, which medication is recommended as
daily maintenance therapy?
A. Short-acting beta-agonist PRN
B. Inhaled corticosteroid
C. Oral antihistamine
D. Leukotriene antagonist PRN
Explanation: Inhaled corticosteroids reduce airway inflammation and
prevent exacerbations.
10.Which of the following is the most appropriate screening test for
hyperlipidemia in adults?
A. Liver function test
B. Blood pressure measurement
C. Fasting lipid panel
D. HbA1c
Explanation: A fasting lipid panel is standard for detecting dyslipidemia.
11.A patient presents with sudden-onset right-sided weakness and slurred
speech. What is the priority action?
A. Obtain an MRI within 48 hours
B. Start antihypertensives immediately
C. Activate stroke protocol and obtain CT scan immediately
D. Give aspirin at home
Explanation: Acute stroke management requires urgent neuroimaging to
differentiate ischemic vs. hemorrhagic stroke.
12.Which of the following contraceptives is most effective at preventing
pregnancy?
, A. Male condom
B. Oral contraceptive pill
C. Implantable progestin device (Nexplanon)
D. Spermicidal gel
Explanation: Long-acting reversible contraception like Nexplanon has the
highest efficacy.
13.A 65-year-old patient reports difficulty sleeping, daytime fatigue, and loud
snoring. Which test is most appropriate?
A. EEG
B. Polysomnography
C. Sleep study (polysomnography)
D. Pulmonary function test
Explanation: Polysomnography is the gold standard for diagnosing sleep
apnea.
14.A patient presents with polyuria, polydipsia, and hyperglycemia. Which type
of diabetes is most likely if they are 16 years old?
A. Type 2 diabetes
B. Gestational diabetes
C. Type 1 diabetes
D. MODY
Explanation: Type 1 diabetes commonly presents in adolescence with
insulin deficiency symptoms.
15.First-line pharmacologic therapy for smoking cessation includes:
A. Bupropion or nicotine replacement therapy
B. Bupropion or varenicline
C. Methadone
D. Naltrexone
Explanation: Bupropion and varenicline are FDA-approved first-line agents
for cessation.
16.A 70-year-old patient presents with sudden onset of severe, unilateral eye
pain and blurred vision. Exam shows mid-dilated pupil. Diagnosis?
UPDATE FAST REVIWED FROM ACTUAL TEST 150 QUESTIONS
AND 100% VERIFIED ANSWERS| A+ GRADE Q&A | INSTANT
DOWNLOAD PDF
1. A 45-year-old patient presents with a persistent cough, fever, and malaise
for 3 weeks. Chest X-ray shows a localized infiltrate in the right lower lobe.
Which is the most likely diagnosis?
A. Community-acquired pneumonia
B. Pulmonary embolism
C. Asthma exacerbation
D. Acute bronchitis
Explanation: Community-acquired pneumonia commonly presents with
fever, productive cough, and localized infiltrates on imaging.
2. Which of the following vaccines is recommended annually for all adults?
A. Tdap
B. Influenza
C. MMR
D. Varicella
Explanation: Influenza vaccine is recommended yearly for all adults to
prevent seasonal flu.
3. A patient with type 2 diabetes reports polyuria, polydipsia, and unexplained
weight loss. Which lab test is most appropriate to confirm diagnosis?
A. Fasting lipid panel
B. Liver function test
C. Hemoglobin A1c
D. Urinalysis
Explanation: Hemoglobin A1c reflects average blood glucose levels over 2–
3 months and is diagnostic for diabetes.
4. Which antihypertensive class is first-line for a patient with chronic kidney
disease?
, A. Calcium channel blockers
B. Beta-blockers
C. ACE inhibitors
D. Diuretics
Explanation: ACE inhibitors slow progression of kidney disease and are
preferred for patients with proteinuria.
5. A 60-year-old patient presents with fatigue, pallor, and spoon-shaped nails.
Lab shows low hemoglobin and microcytosis. What is the most likely cause?
A. Vitamin B12 deficiency
B. Iron deficiency anemia
C. Hemolytic anemia
D. Aplastic anemia
Explanation: Microcytic anemia with pallor and spoon-shaped nails is
characteristic of iron deficiency.
6. A patient on warfarin presents with INR 5.5 and no bleeding. What is the
appropriate next step?
A. Continue warfarin
B. Hold warfarin and monitor INR
C. Administer vitamin B12
D. Start heparin
Explanation: An INR above 5 without bleeding warrants temporary
cessation and close monitoring.
7. Which of the following is the first-line treatment for acute otitis media in
children?
A. Amoxicillin
B. Azithromycin
C. Ciprofloxacin
D. Doxycycline
Explanation: Amoxicillin is first-line unless there is allergy or resistance.
8. A 28-year-old female reports dysuria, frequency, and urgency. Urinalysis
shows leukocyte esterase and nitrites. Which is the most likely diagnosis?
, A. Pyelonephritis
B. Uncomplicated urinary tract infection
C. Interstitial cystitis
D. Kidney stones
Explanation: Dysuria with positive nitrites and leukocyte esterase
indicates a bacterial UTI.
9. For a patient with chronic asthma, which medication is recommended as
daily maintenance therapy?
A. Short-acting beta-agonist PRN
B. Inhaled corticosteroid
C. Oral antihistamine
D. Leukotriene antagonist PRN
Explanation: Inhaled corticosteroids reduce airway inflammation and
prevent exacerbations.
10.Which of the following is the most appropriate screening test for
hyperlipidemia in adults?
A. Liver function test
B. Blood pressure measurement
C. Fasting lipid panel
D. HbA1c
Explanation: A fasting lipid panel is standard for detecting dyslipidemia.
11.A patient presents with sudden-onset right-sided weakness and slurred
speech. What is the priority action?
A. Obtain an MRI within 48 hours
B. Start antihypertensives immediately
C. Activate stroke protocol and obtain CT scan immediately
D. Give aspirin at home
Explanation: Acute stroke management requires urgent neuroimaging to
differentiate ischemic vs. hemorrhagic stroke.
12.Which of the following contraceptives is most effective at preventing
pregnancy?
, A. Male condom
B. Oral contraceptive pill
C. Implantable progestin device (Nexplanon)
D. Spermicidal gel
Explanation: Long-acting reversible contraception like Nexplanon has the
highest efficacy.
13.A 65-year-old patient reports difficulty sleeping, daytime fatigue, and loud
snoring. Which test is most appropriate?
A. EEG
B. Polysomnography
C. Sleep study (polysomnography)
D. Pulmonary function test
Explanation: Polysomnography is the gold standard for diagnosing sleep
apnea.
14.A patient presents with polyuria, polydipsia, and hyperglycemia. Which type
of diabetes is most likely if they are 16 years old?
A. Type 2 diabetes
B. Gestational diabetes
C. Type 1 diabetes
D. MODY
Explanation: Type 1 diabetes commonly presents in adolescence with
insulin deficiency symptoms.
15.First-line pharmacologic therapy for smoking cessation includes:
A. Bupropion or nicotine replacement therapy
B. Bupropion or varenicline
C. Methadone
D. Naltrexone
Explanation: Bupropion and varenicline are FDA-approved first-line agents
for cessation.
16.A 70-year-old patient presents with sudden onset of severe, unilateral eye
pain and blurred vision. Exam shows mid-dilated pupil. Diagnosis?
