NURS 660 Exam 1: 2026/2027 – Psychopharmacology &
Advanced Mental Health | Maryville Actual Questions with
Verified Answers & Detailed Rationales | Grade A
1. What is hyperprolactinemia?
A. Lower-than-normal prolactin levels
B. Higher-than-normal prolactin levels, which may result in spontaneous breastmilk
production and amenorrhea
C. Elevated cortisol levels
D. Elevated thyroid hormone levels
Correct Answer: B
Rationale: Hyperprolactinemia is elevated prolactin levels causing galactorrhea and
amenorrhea.
2. What are the causes of hyperprolactinemia? (Select all that apply.)
A. Pituitary adenoma
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B. Drugs (SSRI, antipsychotics, cocaine)
C. Hypothyroidism
D. Mass effect and trauma
Correct Answer: A, B, C, D
Rationale: Hyperprolactinemia can be caused by adenoma, medications,
hypothyroidism, mass effect, and trauma.
3. What is the treatment for hyperprolactinemia?
A. Antipsychotics
B. Dopamine agonists (cabergoline, bromocriptine)
C. SSRIs
D. Beta-blockers
Correct Answer: B
Rationale: Dopamine agonists such as cabergoline and bromocriptine are used to treat
hyperprolactinemia.
4. What is the benefit of D2 receptor antagonism?
A. Improves negative symptoms
B. Improves positive symptoms
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C. Causes weight loss
D. Decreases prolactin
Correct Answer: B
Rationale: D2 receptor antagonism improves positive symptoms of schizophrenia.
5. What is the side effect of alpha-1 adrenergic receptor antagonism?
A. Sedation
B. Postural hypotension (orthostatic hypotension)
C. Weight gain
D. Hyperprolactinemia
Correct Answer: B
Rationale: Alpha-1 adrenergic antagonism causes orthostatic hypotension.
6. What is the side effect of histamine H1 receptor antagonism?
A. Orthostatic hypotension
B. Sedation
C. Weight loss
D. Hyperprolactinemia
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Correct Answer: B
Rationale: Histamine H1 receptor antagonism causes sedation.
7. What receptors are involved in weight gain?
A. 5HT2A and D2
B. 5HT2C and H1
C. Alpha-1 and D2
D. M1 and 5HT2A
Correct Answer: B
Rationale: Weight gain is associated with 5HT2C antagonism (weight changes) and H1
antagonism (sedation).
8. What are the side effects of alpha-1 adrenergic receptor antagonism? (Select all
that apply.)
A. Orthostatic hypotension
B. Reflex tachycardia
C. Dizziness
D. Weight gain
Correct Answer: A, B, C