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CCTN Review- General Transplantation Care Questions and Answers Updated 2026

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CCTN Review- General Transplantation Care Questions and Answers Updated 2026

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CCTN Review- General
Transplantation Care Questions and
Answers Updated 2026
CholestasisM-
MAnswerMaMconditionMwhereMtheMbileMcannotMflowMfromMtheMliverMtoMtheMduodenu
mMofMtheMsmallMintestines.

IntrahepaticMbileMductM-MAnswerMpassesMthroughMandMdrainMbileMfromMtheMliver.

DiseasesMthatMaffectMtheMIntrahepaticMbileMductMare:M-MAnswerMbiliaryMatresia

PrimaryMbiliaryMcirrhosis

IatrogenicMdrugMinducedMdiseases

FamilialMcholestasis

CysticMfibrosis

BiliaryMatresiaM-
MAnswerMcommonMbileMductMbetweenMtheMliverMandMsmallMintestinesMisMblocked.

PrimaryMbiliaryMcirrhosisM-MAnswerMdiseaseMthatMdestroysMtheMbileMductsMinMtheMliver.

IatrogenicMdrugMinducedMdiseasesM-MAnswerMchlorpromazine

tolbutamide

FamilialMcholestasisM-MAnswerMByler'sMsyndrome

ArteriohepaticMdysplasia

CysticMfibrosisM-
MAnswerMstickyMbuildupMofMmucusMinMtheMintestinesMcanMleadMtoMinspissatedM(thicken
ed,Mdried)MbileMsyndromeMandMcirrhosis.

IDDMM(InsulinMDependentMDiabetesMMellitus)-MBrittleMTypeM1MDiabetes

, (noMsignsMofMadvancedMdiabeticMnephropathy)M-
MAnswerMtheMmostMcommonMdiseaseMthatMrequiresMaMpancreasMtransplant.

alcoholismMwithMliverMchangesM-
MAnswerMmostMcommonMdiseaseMthatMrequireMaMliverMtransplant

cholestasisM-MAnswerMmostMcommonMdiseaseMthatMrequireMaMliverMtransplant

chronicMhepatitisM-MAnswerMmostMcommonMdiseaseMthatMrequireMaMliverMtransplant

geneticMdiseasesM(Crigler-
NajjarMsyndrome,MhereditaryMoxalises,MfamilialMhypercholesterolemia).M-
MAnswerMmostMcommonMdiseaseMthatMrequireMaMliverMtransplant

hepatocellularMcarcinomaM(HCC)-M<5McmMaccompaniedMbyMcirrhosisM-
MAnswerMmostMcommonMdx.MthatMreq.MaMliverMtransplant.

metabolicMdiseaseM-MAnswerMmostMcommonMdx.MthatMreq.MaMliverMtransplant.

CoagulopathyMofMliverMdiseaseM-MAnswerMCirrhosis

ImpairedMhepaticMfunction

*DecreasedMsynthesisMofMclottingMfactorsMII,MV,MVII,MIXMandMfibrinogen*

FactorMVIIIMlevelsMoccasionallyM↑

PTMprolonged,MaPTTMprolongedMinMlongstandingMdisease

*UsuallyMdoesMnotMrequireMtreatmentMunlessMbleedingMcomplicationsMoccur*

FFPMifMactiveMbleedingMwithMprolongedMaPTTMandMPTT

CryoprecipitateMifMfibrinogenM<M80Mmg/dL

organMtransplant

HepaticMencephalopathyM-
MAnswerMimpairedMammoniaMmetabolismMcausesMcerebralMedema.Ms/s:MchangeMinMLOC,
MmemoryMloss,MasterixisM(flappingMtremor)MimpairedMhandwriting,MhyperventilationMw/Mr
espMalkalosis.MRx:Mlactulose,MlowMprotein,Msafety,Mrest

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Uploaded on: March 23, 2026
Number of pages: 11
Written in: 2025/2026
Type: Exam (elaborations)
Contains: Questions & answers

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