WITH 91 QUESTIONS AND CORRECT
ANSWERS RATED A+
First-pass effect
If a large portion of a drug is chemically changed into inactive metabolites in the
liver, then a much smaller amount of drug will pass into the circulation. Reduces
bioavailability of the drug to less than 100 %
Adverse Effect
General term of any undesirable effects that are direct response to one or more
drugs.
Allergic reaction
Immunologic hypersensitivity reaction resulting from the unusual sensitivity of a
patient to a particular medication; type of adverse drug event
Idiosyncratic reaction
An abnormal and unexpected response to a medication, other than allergic
reaction, that Is peculiar to an individual patient
6 rights of medication administration
Right Dose, Right Patient, Right Route, Right Medication, Right Time, Right
Documentation
Pharmachologic reaction
The toxic effect is simply an extension of the pharmacological effect. It is doing
what it is supposed to do just too much
Half-Life
, The time required for half of an administered dose of drug to be eliminated by the
body , or the time it takes for the blood level of a drug to be reduced by 50
percent
Duration of action
The length of time the concentration of a drug in the blood or tissues is sufficient
to elicit a response
Nursing Process
a. An Organizational framework for the practice nursing.
b. Nursing Diagnosis - means communicating and sharing accurate information
regarding patient well being.
c. Assessment-data collection, review, and analyze
d. planning- goals & outcome criteria
e. Implementation- including patient education
f. Evaluation
Bioequivalent
if two products are said to be bioequivalent it means that they would be expected
to be, for all intents and purposes, the same.
Synergistic
it means various parts are working together to produce an enhanced result
a compound that, on administration, must undergo chemical conversion by
metabolic processes before becoming an active pharmacological agent
(start inactive go to the liver)
Prodrugs- activated by ingestion
Steady state
the physiologic state in which the amount of drug removed via elimination is
equal to the amount of the absorbed with each dose. (therapeutic dose)
Selective enzyme interaction