NR565 Advanced Pharmacology Midterm Exam Study
Guide questions and answers 2026\2027 A+ Grade
Drugs that APRNs can prescribe
- correct answer Schedule 3-5 drugs
Determined by State Boards of Nursing, Medicine, and Pharmacy
- correct answer Prescriptive authority regulation
Leads to fewer treatment options for patients, requiring them to find providers with authority
- correct answer Limited prescriptive authority impact
Understanding prescribed drugs, their effects, contraindications, and ensuring correct dosages
- correct answer Key responsibilities of prescribing
Acronym for CYP450 enzyme inducers: Barbiturates, St. John's Wort, Carbamazepine, Rifampin, Alcohol,
Phenytoin, Griseofulvin, Phenobarbital, Sulfonylureas
- correct answer BSCRAP GPS Incudes Rage
Amount of active drug reaching systemic circulation from administration site
- correct answer Bioavailability
Include forgetfulness, lack of planning, cost, dissatisfaction, and altered dosing
- correct answer Reasons for medication nonadherence
Absorption is slow in neonates due to low muscle blood flow; absorption becomes rapid in early infancy
- correct answer IM administration in neonates and infants
Gastric emptying time is prolonged and irregular in early infancy, affecting drug absorption
- correct answer Oral administration in neonates/infants
, Based on body surface area (BSA) calculation
- correct answer Dosage determination for pediatric patients
Steps include defining the problem, setting therapeutic objectives, choosing treatment, verifying its
suitability, starting treatment, giving information, and monitoring treatment
- correct answer Guiding principles for prescribers
Examples include Valproate, Isoniazid, Sulfonamides, Amiodarone, Chloramphenicol, Ketoconazole,
Grapefruit juice, Quinidine
- correct answer CYP450 inhibitors
Basis for prescribing decisions, considering drug interactions and effects on target receptors
- correct answer Pharmacokinetics and pharmacodynamics
Tool identifying inappropriate medication use in older adults, cautioning against certain drugs and
interactions
- correct answer Beer's Criteria
Include adverse drug events, increased healthcare interactions, cognitive impairment, reduced
adherence, falls, and mortality
- correct answer Impacts of polypharmacy
They decrease medication metabolism
- correct answer CYP450 inhibitors function
May cause toxicity if enzymes are inactive or ineffectiveness if enzymes are overactive
- correct answer CYP450 inhibitors consequences
Occurs when CYP2D6 alleles have inactivating mutations, leading to enzyme synthesis with impaired or
no activity
- correct answer Poor metabolism phenotype
Guide questions and answers 2026\2027 A+ Grade
Drugs that APRNs can prescribe
- correct answer Schedule 3-5 drugs
Determined by State Boards of Nursing, Medicine, and Pharmacy
- correct answer Prescriptive authority regulation
Leads to fewer treatment options for patients, requiring them to find providers with authority
- correct answer Limited prescriptive authority impact
Understanding prescribed drugs, their effects, contraindications, and ensuring correct dosages
- correct answer Key responsibilities of prescribing
Acronym for CYP450 enzyme inducers: Barbiturates, St. John's Wort, Carbamazepine, Rifampin, Alcohol,
Phenytoin, Griseofulvin, Phenobarbital, Sulfonylureas
- correct answer BSCRAP GPS Incudes Rage
Amount of active drug reaching systemic circulation from administration site
- correct answer Bioavailability
Include forgetfulness, lack of planning, cost, dissatisfaction, and altered dosing
- correct answer Reasons for medication nonadherence
Absorption is slow in neonates due to low muscle blood flow; absorption becomes rapid in early infancy
- correct answer IM administration in neonates and infants
Gastric emptying time is prolonged and irregular in early infancy, affecting drug absorption
- correct answer Oral administration in neonates/infants
, Based on body surface area (BSA) calculation
- correct answer Dosage determination for pediatric patients
Steps include defining the problem, setting therapeutic objectives, choosing treatment, verifying its
suitability, starting treatment, giving information, and monitoring treatment
- correct answer Guiding principles for prescribers
Examples include Valproate, Isoniazid, Sulfonamides, Amiodarone, Chloramphenicol, Ketoconazole,
Grapefruit juice, Quinidine
- correct answer CYP450 inhibitors
Basis for prescribing decisions, considering drug interactions and effects on target receptors
- correct answer Pharmacokinetics and pharmacodynamics
Tool identifying inappropriate medication use in older adults, cautioning against certain drugs and
interactions
- correct answer Beer's Criteria
Include adverse drug events, increased healthcare interactions, cognitive impairment, reduced
adherence, falls, and mortality
- correct answer Impacts of polypharmacy
They decrease medication metabolism
- correct answer CYP450 inhibitors function
May cause toxicity if enzymes are inactive or ineffectiveness if enzymes are overactive
- correct answer CYP450 inhibitors consequences
Occurs when CYP2D6 alleles have inactivating mutations, leading to enzyme synthesis with impaired or
no activity
- correct answer Poor metabolism phenotype
