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CSMLS practice questions with correct answers 100% 2026

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CSMLS practice questions with correct answers 100% 2026 Which of the following actions should be taken when the hematoxylin and eosin stain lacks three distinct shades of pink? a. check pH of fixative b. replace hematoxylin c. check pH of eosin d. increase time in water - Correct Answer c. check pH of eosin A dark brown pigment is noted on formalin fixed, hematoxylin and eosin stained section. What action can prevent this from occurring? a. maintain formalin at a neutral pH b. treat sections with alcoholic picric acid c. "bread loaf" large sections d. increase fixation time - Correct Answer a. maintain formalin at a neutral pH Which of the following actions should be taken when a supervisor continuously assigns a technologist demeaning tasks? a. accept the change in tasks b. confront the supervisor publicly c. seek third party mediation d. criticize the supervisor to other colleagues - Correct Answer c. seek third party mediation Which of the following actions should be taken when tissue sections stained with hematoxylin and eosin show pale cytoplasmic staining a. use heat during the staining process b. check the pH of the eosin and adjust the sodium hydroxide if necessary c. return the slides to the bluing reagent d. check the pH of eosin and adjust with acetic acid if necessary - Correct Answer d. check the pH of eosin and adjust with acetic acid if necessary Which of the following statements is consistent with the results given below? PLEURAL FLUID - total nucleated cell count: markedly increased - smear: numerous clumps of large cells without borders a. repeat the total nucleated cell count b. report as clotted specimen c. suspicious of malignant cells d. presence of the mesothelial cells - Correct Answer c. suspicious of malignant cells Which of the following actions should be taken when a technologist is disrespectful to a nurse who is consistently interrupting their work? a. file an occurrence report b. engage in role clarification c. organize work to accommodate priorities d. engage in reflective practice - Correct Answer d. engage in reflective practice Which of the following actions can account for the presence of Gram negative cocci in chains from a blood culture? a. under decolorization of the smear b. omission of the counterstain step c. drying of the smear prior to staining d. overheating of the smear during fixation - Correct Answer a. under decolorization of the smear Where should a tissue specimen for frozen section be sent? a. cytology b. chemistry c. histology d. microbiology - Correct Answer c. histology What is the proper order for removal of personal protective equipment? a. gloves, mask, eye protection, gown b. gown, gloves, eye protection, mask c. gown, mask, gloves, eye protection d. gloves, gown, eye protection, mask - Correct Answer d. gloves, gown, eye protection, mask What is the most important step in preventing infection? a. wearing gloves b. hand washing c. wearing N95 mask d. disinfecting surfaces - Correct Answer b. hand washing Which of the following actions is considered negligence? a. touching a patient without consent b. failing to report a critical value c. making a negative statement about a colleague d. reporting child abuse - Correct Answer b: failing to report a critical value How should a technologist proceed when collecting a blood sample from a patient who is terminating a pregnancy? a. collect the patients blood b. discuss the surgical procedure with the patient c. refuse to collect from this patient as it violates strongly held beliefs d. collect the blood sample but avoid eye contact with the patient - Correct Answer a. collect the patients blood Which of the following disinfectant must not be place in

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Which of the following actions should be taken when the hematoxylin and eosin stain lacks three
distinct shades of pink?

a. check pH of fixative

b. replace hematoxylin

c. check pH of eosin

d. increase time in water - Correct Answer c. check pH of eosin



A dark brown pigment is noted on formalin fixed, hematoxylin and eosin stained section. What action
can prevent this from occurring?

a. maintain formalin at a neutral pH

b. treat sections with alcoholic picric acid

c. "bread loaf" large sections

d. increase fixation time - Correct Answer a. maintain formalin at a neutral pH



Which of the following actions should be taken when a supervisor continuously assigns a technologist
demeaning tasks?

a. accept the change in tasks

b. confront the supervisor publicly

c. seek third party mediation

d. criticize the supervisor to other colleagues - Correct Answer c. seek third party mediation



Which of the following actions should be taken when tissue sections stained with hematoxylin and eosin
show pale cytoplasmic staining

a. use heat during the staining process

b. check the pH of the eosin and adjust the sodium hydroxide if necessary

c. return the slides to the bluing reagent

d. check the pH of eosin and adjust with acetic acid if necessary - Correct Answer d. check the pH of
eosin and adjust with acetic acid if necessary

,Which of the following statements is consistent with the results given below?

PLEURAL FLUID

- total nucleated cell count: markedly increased

- smear: numerous clumps of large cells without borders



a. repeat the total nucleated cell count

b. report as clotted specimen

c. suspicious of malignant cells

d. presence of the mesothelial cells - Correct Answer c. suspicious of malignant cells



Which of the following actions should be taken when a technologist is disrespectful to a nurse who is
consistently interrupting their work?

a. file an occurrence report

b. engage in role clarification

c. organize work to accommodate priorities

d. engage in reflective practice - Correct Answer d. engage in reflective practice



Which of the following actions can account for the presence of Gram negative cocci in chains from a
blood culture?

a. under decolorization of the smear

b. omission of the counterstain step

c. drying of the smear prior to staining

d. overheating of the smear during fixation - Correct Answer a. under decolorization of the smear



Where should a tissue specimen for frozen section be sent?

a. cytology

b. chemistry

c. histology

, d. microbiology - Correct Answer c. histology



What is the proper order for removal of personal protective equipment?

a. gloves, mask, eye protection, gown

b. gown, gloves, eye protection, mask

c. gown, mask, gloves, eye protection

d. gloves, gown, eye protection, mask - Correct Answer d. gloves, gown, eye protection, mask



What is the most important step in preventing infection?

a. wearing gloves

b. hand washing

c. wearing N95 mask

d. disinfecting surfaces - Correct Answer b. hand washing



Which of the following actions is considered negligence?

a. touching a patient without consent

b. failing to report a critical value

c. making a negative statement about a colleague

d. reporting child abuse - Correct Answer b: failing to report a critical value



How should a technologist proceed when collecting a blood sample from a patient who is terminating a
pregnancy?

a. collect the patients blood

b. discuss the surgical procedure with the patient

c. refuse to collect from this patient as it violates strongly held beliefs

d. collect the blood sample but avoid eye contact with the patient - Correct Answer a. collect the
patients blood



Which of the following disinfectant must not be place in autoclave due to generation of unsafe gases?

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