D116 WGU ADVANCED PHARMACOLOGY FULL
SCRIPT 2026 QUESTIONS WITH SOLUTIONS AND
GRADING
▶ What medication used to treat alcohol use disorder can be safely
administered to patients with hepatitis and/or liver disease?
Answer:Acamprosate
▶ What medication used to treat alcohol use disorder is contraindicated
with severe renal disease?? Answer:Acamprosate
▶ Aversion symptoms with Disulfuram? Answer:flushing, N/V, HA, vertigo,
SOB, hypotension, palpitation
▶ How long do you need to wait to administer antabuse?? Answer:Person
needs to be alcohol free for 12 hours
▶ Important Education for patients taking Disulfuram? Answer:Do not use
anything that contains alcohol: mouthwash, aftershave, perfumes, vinegar,
cough medicine for up to two weeks after last dose of disulfuram
▶ What is given to prevent Wernicke's encephalopathy??
Answer:Thiamine (Vit B1) to compensate for Vit B1 deficiency
▶ What should be given to pts with alcohol use disorder for nutritional
deficiencies? Answer:thiamine, folate/folic acid,
▶ First line treatment in alcohol withdrawal? Answer:Benzodiazepines
▶ Long acting benzo for etoh withdrawal? Answer:diazepam (Valium)
▶ Short acting benzo for etoh withdrawal? Answer:lorazepam (Ativan)
▶ Additional medications to use in mild to moderate alcohol withdrawal?
Answer:carbamazepine (Tegretol), Valproic acid or gabapentin
, ▶ MOA of Naloxone (Narcan)? Answer:competitive opioid receptor
antagonist
▶ MOA of naltrexone? Answer:competitive opioid receptor antagonist
▶ MOA of Methadone (Dolophine)? Answer:long acting FULL opioid
receptor agonist (at mu receptor)
▶ MOA of Suboxone (buprenorphine and naloxone)? Answer:partial opioid
agonist + competitive opioid antagonist
▶ Medication used in opioid overdose? Answer:naloxone
▶ Medication used in patients with chronic pain and opioid use disorder?
Answer:Suboxone (buprenorphine and naloxone)
▶ Which medications for opioid use disorder can precipitate withdrawal?
Answer:naloxone, naltrexone, Suboxone (buprenorphine)
▶ Which medication used to treat opioid use disorder has a "ceiling
effect"?? Answer:Buprenorphine... increasing the dose does not result in
increasing effects
▶ Which medication is available sublingual film/tab and buccal film for
opioid patients? Answer:Suboxone
▶ Which medication is available as sublingual tab, implant, and subQ
injection for opioid patients? Answer:Buprenorphine
▶ Which medication is available as a oral tablet and a monthly IM injection
for opioid patients?? Answer:Naltrexone
▶ Which medication is treatment of choice for highly motivated opioid use
disorder patients?? Answer:Naltrexone
▶ Inappropriate use of opioids may indicate? Answer:the patient's pain is
not well managed
SCRIPT 2026 QUESTIONS WITH SOLUTIONS AND
GRADING
▶ What medication used to treat alcohol use disorder can be safely
administered to patients with hepatitis and/or liver disease?
Answer:Acamprosate
▶ What medication used to treat alcohol use disorder is contraindicated
with severe renal disease?? Answer:Acamprosate
▶ Aversion symptoms with Disulfuram? Answer:flushing, N/V, HA, vertigo,
SOB, hypotension, palpitation
▶ How long do you need to wait to administer antabuse?? Answer:Person
needs to be alcohol free for 12 hours
▶ Important Education for patients taking Disulfuram? Answer:Do not use
anything that contains alcohol: mouthwash, aftershave, perfumes, vinegar,
cough medicine for up to two weeks after last dose of disulfuram
▶ What is given to prevent Wernicke's encephalopathy??
Answer:Thiamine (Vit B1) to compensate for Vit B1 deficiency
▶ What should be given to pts with alcohol use disorder for nutritional
deficiencies? Answer:thiamine, folate/folic acid,
▶ First line treatment in alcohol withdrawal? Answer:Benzodiazepines
▶ Long acting benzo for etoh withdrawal? Answer:diazepam (Valium)
▶ Short acting benzo for etoh withdrawal? Answer:lorazepam (Ativan)
▶ Additional medications to use in mild to moderate alcohol withdrawal?
Answer:carbamazepine (Tegretol), Valproic acid or gabapentin
, ▶ MOA of Naloxone (Narcan)? Answer:competitive opioid receptor
antagonist
▶ MOA of naltrexone? Answer:competitive opioid receptor antagonist
▶ MOA of Methadone (Dolophine)? Answer:long acting FULL opioid
receptor agonist (at mu receptor)
▶ MOA of Suboxone (buprenorphine and naloxone)? Answer:partial opioid
agonist + competitive opioid antagonist
▶ Medication used in opioid overdose? Answer:naloxone
▶ Medication used in patients with chronic pain and opioid use disorder?
Answer:Suboxone (buprenorphine and naloxone)
▶ Which medications for opioid use disorder can precipitate withdrawal?
Answer:naloxone, naltrexone, Suboxone (buprenorphine)
▶ Which medication used to treat opioid use disorder has a "ceiling
effect"?? Answer:Buprenorphine... increasing the dose does not result in
increasing effects
▶ Which medication is available sublingual film/tab and buccal film for
opioid patients? Answer:Suboxone
▶ Which medication is available as sublingual tab, implant, and subQ
injection for opioid patients? Answer:Buprenorphine
▶ Which medication is available as a oral tablet and a monthly IM injection
for opioid patients?? Answer:Naltrexone
▶ Which medication is treatment of choice for highly motivated opioid use
disorder patients?? Answer:Naltrexone
▶ Inappropriate use of opioids may indicate? Answer:the patient's pain is
not well managed
