CPHON Study Guide Questions With Correct
Answers
What |does |Hydroxyurea |stimulate? |- |CORRECT |ANSWER✔✔-fetal |hgb
What |is |Rituximab? |- |CORRECT |ANSWER✔✔-Monoclonal |antibody
acts |against |CD20
used |for |Burkitts |Lymphoma
Where |is |erythropoietin |produced? |- |CORRECT |ANSWER✔✔-kidneys
epryhropoietin: |regulates |and |controls |the |production |of |maturation |of |RBCs
What |is |Septra |and |Dapsone |for? |- |CORRECT |ANSWER✔✔-to |prevent |pneumocystis |jiroveci.
What |can |Septra |(Bactrim) |cause? |- |CORRECT |ANSWER✔✔-bone |marrow |suppression
Imatinib |is |best |treatment |for.... |- |CORRECT |ANSWER✔✔-CML
What |can |Tacrolimus |cause? |- |CORRECT |ANSWER✔✔-reversible |posterior |encephalopathy
Dactinomycin |can |cause? |- |CORRECT |ANSWER✔✔-radiation |recall
Bleomycin |can |cause? |- |CORRECT |ANSWER✔✔-pulmonary |fibrosis. |Make |sure |to |tell |
anesthesia |before |being |put |to |sleep. |You |cannot |hyper |oxygenate |bc |it |will |make |it |worse.
,What |chemos |have |a |max |dose? |- |CORRECT |ANSWER✔✔-Bleomycin |
Doxorubicin |550mg/m2
What |can |Asparaginase |cause? |- |CORRECT |ANSWER✔✔-Pancreatitis |and |High |blood |sugar
What |can |VP16 |cause? |- |CORRECT |ANSWER✔✔-secondary |AML
Alkylating |agents |are |responsible |for... |- |CORRECT |ANSWER✔✔-fertility |issues. |Think |of |
transplant |chemos |and |high |dose |chemos |like |cisplatin, |ifosphamide
What |is |the |first |line |of |treatment |for |hemolytic |anemia? |- |CORRECT |ANSWER✔✔-Steroids
What |drug |is |given |for |iron |overload? |- |CORRECT |ANSWER✔✔-Deferoxamine |it |is |a |chelating |
agent
Most |common |childhood |cancer? |- |CORRECT |ANSWER✔✔-ALL
Most |common |solid |tumor |cancer? |- |CORRECT |ANSWER✔✔-Brain |tumors
Astrocytoma: |most |common |brain |tumor
Medulloblastoma: |most |common |malignant |brain |tumor
Most |common |extracranial |solid |tumor? |- |CORRECT |ANSWER✔✔-NB
Alkylating |Agents.... |- |CORRECT |ANSWER✔✔-interrupts |the |cell |cycle
cytoxan |(cycle)
Ifosfamide
,Lomustine
Carmustine
Buslfan
Procarbazine
Temozolimide
Decarbazine
Cisplatin
Carboplatin
Antitumor |Antiboitics.... |- |CORRECT |ANSWER✔✔-interfere |with |cell |metabolism
Dactinomycin
Bleomycin
Daunorubicin
Doxorubicin
Idarubicin
Antimetabolites.... |- |CORRECT |ANSWER✔✔-Stops |the |ability |at |the |nucleus
5FU
6MP
Gemcitabine
Fludarabine
Cytrarbine
Hydroxyurea
Methotrexate
Plant |Alkaloids.... |- |CORRECT |ANSWER✔✔-cause |DNA |breakdown
, VP16
Paclitaxel
Docetaxel
Topotecan
Irinotecan
Vincristine:max |single |dose |2mg
Vinblastine
Vinorelbine
Miscellaneous... |- |CORRECT |ANSWER✔✔-mechanisms |not |understood |
Asparaginase
Retinoids
Imatinib |(Gleevac)
Ambisome |- |CORRECT |ANSWER✔✔-antifungal
check |K
think |about |pt |on |antibiotics |for |1 |week |and |still |having |F/N |think |fungal
What |are |Biologic |Response |Modifiers |(BRM)? |- |CORRECT |ANSWER✔✔-attack |targeted |
pathways |and |tumor |receptor |sites
What |scan |is |gold |standard |with |NB? |- |CORRECT |ANSWER✔✔-MIBG
What |is |Flagyl |used |for? |- |CORRECT |ANSWER✔✔-Cdiff
Answers
What |does |Hydroxyurea |stimulate? |- |CORRECT |ANSWER✔✔-fetal |hgb
What |is |Rituximab? |- |CORRECT |ANSWER✔✔-Monoclonal |antibody
acts |against |CD20
used |for |Burkitts |Lymphoma
Where |is |erythropoietin |produced? |- |CORRECT |ANSWER✔✔-kidneys
epryhropoietin: |regulates |and |controls |the |production |of |maturation |of |RBCs
What |is |Septra |and |Dapsone |for? |- |CORRECT |ANSWER✔✔-to |prevent |pneumocystis |jiroveci.
What |can |Septra |(Bactrim) |cause? |- |CORRECT |ANSWER✔✔-bone |marrow |suppression
Imatinib |is |best |treatment |for.... |- |CORRECT |ANSWER✔✔-CML
What |can |Tacrolimus |cause? |- |CORRECT |ANSWER✔✔-reversible |posterior |encephalopathy
Dactinomycin |can |cause? |- |CORRECT |ANSWER✔✔-radiation |recall
Bleomycin |can |cause? |- |CORRECT |ANSWER✔✔-pulmonary |fibrosis. |Make |sure |to |tell |
anesthesia |before |being |put |to |sleep. |You |cannot |hyper |oxygenate |bc |it |will |make |it |worse.
,What |chemos |have |a |max |dose? |- |CORRECT |ANSWER✔✔-Bleomycin |
Doxorubicin |550mg/m2
What |can |Asparaginase |cause? |- |CORRECT |ANSWER✔✔-Pancreatitis |and |High |blood |sugar
What |can |VP16 |cause? |- |CORRECT |ANSWER✔✔-secondary |AML
Alkylating |agents |are |responsible |for... |- |CORRECT |ANSWER✔✔-fertility |issues. |Think |of |
transplant |chemos |and |high |dose |chemos |like |cisplatin, |ifosphamide
What |is |the |first |line |of |treatment |for |hemolytic |anemia? |- |CORRECT |ANSWER✔✔-Steroids
What |drug |is |given |for |iron |overload? |- |CORRECT |ANSWER✔✔-Deferoxamine |it |is |a |chelating |
agent
Most |common |childhood |cancer? |- |CORRECT |ANSWER✔✔-ALL
Most |common |solid |tumor |cancer? |- |CORRECT |ANSWER✔✔-Brain |tumors
Astrocytoma: |most |common |brain |tumor
Medulloblastoma: |most |common |malignant |brain |tumor
Most |common |extracranial |solid |tumor? |- |CORRECT |ANSWER✔✔-NB
Alkylating |Agents.... |- |CORRECT |ANSWER✔✔-interrupts |the |cell |cycle
cytoxan |(cycle)
Ifosfamide
,Lomustine
Carmustine
Buslfan
Procarbazine
Temozolimide
Decarbazine
Cisplatin
Carboplatin
Antitumor |Antiboitics.... |- |CORRECT |ANSWER✔✔-interfere |with |cell |metabolism
Dactinomycin
Bleomycin
Daunorubicin
Doxorubicin
Idarubicin
Antimetabolites.... |- |CORRECT |ANSWER✔✔-Stops |the |ability |at |the |nucleus
5FU
6MP
Gemcitabine
Fludarabine
Cytrarbine
Hydroxyurea
Methotrexate
Plant |Alkaloids.... |- |CORRECT |ANSWER✔✔-cause |DNA |breakdown
, VP16
Paclitaxel
Docetaxel
Topotecan
Irinotecan
Vincristine:max |single |dose |2mg
Vinblastine
Vinorelbine
Miscellaneous... |- |CORRECT |ANSWER✔✔-mechanisms |not |understood |
Asparaginase
Retinoids
Imatinib |(Gleevac)
Ambisome |- |CORRECT |ANSWER✔✔-antifungal
check |K
think |about |pt |on |antibiotics |for |1 |week |and |still |having |F/N |think |fungal
What |are |Biologic |Response |Modifiers |(BRM)? |- |CORRECT |ANSWER✔✔-attack |targeted |
pathways |and |tumor |receptor |sites
What |scan |is |gold |standard |with |NB? |- |CORRECT |ANSWER✔✔-MIBG
What |is |Flagyl |used |for? |- |CORRECT |ANSWER✔✔-Cdiff