ATI GASTROINTESTINAL SYSTEM ACTUAL
EXAMINATION 2026 COMPREHENSIVE
QUESTIONS WITH PRECISE SOLUTIONS
AND EXPERT VERIFICATION GRADED A+
⩥ Q: What are adverse drug reactions associated with sulfasalazine?
Answer: A:
Headache
Pneumonitis
Anorexia, nausea, vomiting, diarrhea, drug-induced hepatitis
Crystalluria, infertility, oligospermia, orange-yellow discoloration of
urine
Exfoliative dermatitis, Stevens-Johnson Syndrome, toxic epidermal
necrolysis, rash, photosensitivity, yellow discoloration of urine
Agranulocytosis, aplastic anemia, blood dyscrasias, eosinophilia,
hemolytic anemia, megaloblastic anemia, thrombocytopenia,
Peripheral neuropathy
Angioedema
Hypersensitivity reactions including anaphylaxis
Fever
⩥ Q: What is the brand/trade name for sulfasalazine? Answer: A:
Azulfidine
,⩥ Q: What administration considerations apply to alosetron? Answer: A:
Make sure clients meet specific criteria and sign the required treatment
agreement before administration.
Risk management program
Client, provider, pharmacist
Outlines potential adverse effects
Outlines criteria that must be met for treatment
Only for women who did not improve with traditional therapies
Give orally twice daily.
Reevaluate after 4 weeks without improvement and recommend an
increased dosage if the client is tolerating the drug.
Stop therapy after 8 weeks if diarrhea persists.
⩥ Q: What administration considerations apply to aluminum hydroxide?
Answer: A:
Administer orally up to four times a day.
Make sure clients chew tablets thoroughly and follow with at least 8 oz
of water
Do not give within 1 to 2 hr of administering drugs that interact with
antacids.
⩥ Q: What administration considerations apply to dimenhydrinate?
Answer: A:
,Give dimenhydrinate orally, IM, or IV.
Give the initial dose 30 to 60 min before the activity that triggers nausea.
Give subsequent doses before meals and at bedtime.
Make sure clients do not swallow chewable tablets whole.
⩥ Q: What administration considerations apply to psyllium? Answer: A:
Give orally one to three times a day with at least 8 oz of fluid.
Mix powdered forms with 8 oz of fluid.
Expect soft, formed stools 1 to 3 days after initiating therapy.
Tell clients that taking it before meals might reduce appetite.
⩥ Q: What administration considerations apply to ranitidine
hydrochloride? Answer: A:
Give orally, IM, or IV.
Give with or without food (given with meals, immediately afterwards, or
at bedtime does prolong effect).
Administer IV preparation slowly to avoid bradycardia.
Do not give antacids within 1 hr of administration.
Make sure clients dissolve effervescent tablets in water and do not chew
them, swallow them whole, or allow them to dissolve on the tongue.
⩥ Q: What administration considerations apply to azathioprine? Answer:
A:
, Give orally or IV.
Give oral forms with food to minimize gastrointestinal upset.
Expect the onset of therapeutic effects to take up to 6 months.
⩥ Q: What administration considerations apply to lubiprostone? Answer:
A:
Give orally twice a day with food or water to minimize nausea.
Make sure clients swallow the capsule whole.
Do not administer if client is experiencing diarrhea
⩥ Q: What administration considerations apply to sucralfate? Answer:
A:
Administer orally on an empty stomach.
Give four times a day, 1 hr before the usual three mealtimes and again at
bedtime.
Do not give antacids within 30 min of administration.
Do not give within 2 hr of administering fluoroquinolone antibiotics,
warfarin (Coumadin), phenytoin (Dilantin), theophylline (Theolair),
digoxin (Lanoxin), tetracycline, or diazepam (Valium).
⩥ Q: What administration considerations apply to
diphenoxylate/atropine and loperamide? Answer: A:
Diphenoxylate/atropine
Give orally.
EXAMINATION 2026 COMPREHENSIVE
QUESTIONS WITH PRECISE SOLUTIONS
AND EXPERT VERIFICATION GRADED A+
⩥ Q: What are adverse drug reactions associated with sulfasalazine?
Answer: A:
Headache
Pneumonitis
Anorexia, nausea, vomiting, diarrhea, drug-induced hepatitis
Crystalluria, infertility, oligospermia, orange-yellow discoloration of
urine
Exfoliative dermatitis, Stevens-Johnson Syndrome, toxic epidermal
necrolysis, rash, photosensitivity, yellow discoloration of urine
Agranulocytosis, aplastic anemia, blood dyscrasias, eosinophilia,
hemolytic anemia, megaloblastic anemia, thrombocytopenia,
Peripheral neuropathy
Angioedema
Hypersensitivity reactions including anaphylaxis
Fever
⩥ Q: What is the brand/trade name for sulfasalazine? Answer: A:
Azulfidine
,⩥ Q: What administration considerations apply to alosetron? Answer: A:
Make sure clients meet specific criteria and sign the required treatment
agreement before administration.
Risk management program
Client, provider, pharmacist
Outlines potential adverse effects
Outlines criteria that must be met for treatment
Only for women who did not improve with traditional therapies
Give orally twice daily.
Reevaluate after 4 weeks without improvement and recommend an
increased dosage if the client is tolerating the drug.
Stop therapy after 8 weeks if diarrhea persists.
⩥ Q: What administration considerations apply to aluminum hydroxide?
Answer: A:
Administer orally up to four times a day.
Make sure clients chew tablets thoroughly and follow with at least 8 oz
of water
Do not give within 1 to 2 hr of administering drugs that interact with
antacids.
⩥ Q: What administration considerations apply to dimenhydrinate?
Answer: A:
,Give dimenhydrinate orally, IM, or IV.
Give the initial dose 30 to 60 min before the activity that triggers nausea.
Give subsequent doses before meals and at bedtime.
Make sure clients do not swallow chewable tablets whole.
⩥ Q: What administration considerations apply to psyllium? Answer: A:
Give orally one to three times a day with at least 8 oz of fluid.
Mix powdered forms with 8 oz of fluid.
Expect soft, formed stools 1 to 3 days after initiating therapy.
Tell clients that taking it before meals might reduce appetite.
⩥ Q: What administration considerations apply to ranitidine
hydrochloride? Answer: A:
Give orally, IM, or IV.
Give with or without food (given with meals, immediately afterwards, or
at bedtime does prolong effect).
Administer IV preparation slowly to avoid bradycardia.
Do not give antacids within 1 hr of administration.
Make sure clients dissolve effervescent tablets in water and do not chew
them, swallow them whole, or allow them to dissolve on the tongue.
⩥ Q: What administration considerations apply to azathioprine? Answer:
A:
, Give orally or IV.
Give oral forms with food to minimize gastrointestinal upset.
Expect the onset of therapeutic effects to take up to 6 months.
⩥ Q: What administration considerations apply to lubiprostone? Answer:
A:
Give orally twice a day with food or water to minimize nausea.
Make sure clients swallow the capsule whole.
Do not administer if client is experiencing diarrhea
⩥ Q: What administration considerations apply to sucralfate? Answer:
A:
Administer orally on an empty stomach.
Give four times a day, 1 hr before the usual three mealtimes and again at
bedtime.
Do not give antacids within 30 min of administration.
Do not give within 2 hr of administering fluoroquinolone antibiotics,
warfarin (Coumadin), phenytoin (Dilantin), theophylline (Theolair),
digoxin (Lanoxin), tetracycline, or diazepam (Valium).
⩥ Q: What administration considerations apply to
diphenoxylate/atropine and loperamide? Answer: A:
Diphenoxylate/atropine
Give orally.
