PSY 627 Exam 2 fully solved & updated (latest
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Terms in this set (48)
Reuptake process by which neurotransmitters are taken
back into the synaptic vesicles
Catecholamines: What are they? A group of neurotransmitters and hormones that
How are excess catecholamines share a core structure of a catechol ring and a
removed? Packaging? Monoamine nitrogen-containing amine group. They are
reuptake and blocking reuptake packaged in synaptic vesicles and removed by
reuptake. MAO is involved in the breakdown of
catecholamines; non-selective MAO inhibitors
block MAO-A and MAO-B which are in drugs
used to treat depression.
Vesicle repackaging of dopamine The critical process where the vesicular
monoamine transporter-2 (VMAT2) moves
cytosolic dopamine into synaptic vesicles for
storage and release, utilizing an -ATPase-driven
proton gradient. This mechanism protects cells
from oxidative damage caused by cytoplasmic
dopamine and is essential for maintaining
neurotransmission.
Drugs that bypass excitation Amphetamine and Methamphetamine
, Method of Action of Cocaine Catecholamine reuptake inhibitor
Method of action of ADHD Amphetamine - Catecholamine releaser and
stimulant medications reuptake blocker. Methylphenidate -
Catecholamine reuptake blocker
Norepinephrine A neurotransmitter involved in arousal, as well as
in learning and mood regulation
Noradrenergic system: what is CNS - found in the brainstem (pons (LC) and
norepinephrine, what does it do? medulla) and goes through forebrain structures
Which brain structure is it (cortex, limbic system, thalamus, and
associated with? hypothalamus). PNS - In the ganglia of the
sympathetic branch of the ANS. NE regulates the
"fight or flight" response
Amygdala A limbic system structure involved in memory
and emotion, particularly fear and aggression.
Agonists for serotonin Selective Serotonin Reuptake Inhibitors (SSRIs)
MDMA (initial synthesis, treatment Initial synthesis - stop bleeding. Treatment
implications, acute action) implications - Proposed treatment for severe
PTSD. Acute action - releases serotonin
Serotonin/Serotonergic System: Serotonin: Neurotransmitter 5
which drugs increase it? Hydroxytryptophan (5-HTP)
What does MDMA do? Where are Serotonin in the CNS is found along the midline
the cell bodies that produce of the brainstem (Medulla, pons, midbrain, raphe
serotonin? Serotonin is released in nuclei). Cell bodies that produce serotonin are in
the gut by what? Serotonin in the the raphe nuclei.
CNS? Serotonin is released in the gut by eating.
version verified for accuracy) (Questions +
Answers) Solved 100% Correct!!
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Terms in this set (48)
Reuptake process by which neurotransmitters are taken
back into the synaptic vesicles
Catecholamines: What are they? A group of neurotransmitters and hormones that
How are excess catecholamines share a core structure of a catechol ring and a
removed? Packaging? Monoamine nitrogen-containing amine group. They are
reuptake and blocking reuptake packaged in synaptic vesicles and removed by
reuptake. MAO is involved in the breakdown of
catecholamines; non-selective MAO inhibitors
block MAO-A and MAO-B which are in drugs
used to treat depression.
Vesicle repackaging of dopamine The critical process where the vesicular
monoamine transporter-2 (VMAT2) moves
cytosolic dopamine into synaptic vesicles for
storage and release, utilizing an -ATPase-driven
proton gradient. This mechanism protects cells
from oxidative damage caused by cytoplasmic
dopamine and is essential for maintaining
neurotransmission.
Drugs that bypass excitation Amphetamine and Methamphetamine
, Method of Action of Cocaine Catecholamine reuptake inhibitor
Method of action of ADHD Amphetamine - Catecholamine releaser and
stimulant medications reuptake blocker. Methylphenidate -
Catecholamine reuptake blocker
Norepinephrine A neurotransmitter involved in arousal, as well as
in learning and mood regulation
Noradrenergic system: what is CNS - found in the brainstem (pons (LC) and
norepinephrine, what does it do? medulla) and goes through forebrain structures
Which brain structure is it (cortex, limbic system, thalamus, and
associated with? hypothalamus). PNS - In the ganglia of the
sympathetic branch of the ANS. NE regulates the
"fight or flight" response
Amygdala A limbic system structure involved in memory
and emotion, particularly fear and aggression.
Agonists for serotonin Selective Serotonin Reuptake Inhibitors (SSRIs)
MDMA (initial synthesis, treatment Initial synthesis - stop bleeding. Treatment
implications, acute action) implications - Proposed treatment for severe
PTSD. Acute action - releases serotonin
Serotonin/Serotonergic System: Serotonin: Neurotransmitter 5
which drugs increase it? Hydroxytryptophan (5-HTP)
What does MDMA do? Where are Serotonin in the CNS is found along the midline
the cell bodies that produce of the brainstem (Medulla, pons, midbrain, raphe
serotonin? Serotonin is released in nuclei). Cell bodies that produce serotonin are in
the gut by what? Serotonin in the the raphe nuclei.
CNS? Serotonin is released in the gut by eating.
