NSG5003 CERTIFICATION PAPER 2026
FULL SOLUTION GRADED A+
● A hypersensitivity reaction that produces an allergic response is
called:. Answer: Anaphylaxis
● The common hay fever allergy is expressed through a reaction that is
mediated by which class of immunoglobulins?. Answer: IgE
● Which type of antibody is involved in type I hypersensitivity
reaction?. Answer: IgE
● Blood transfusion reactions are an example of:. Answer: Alloimmunity
● During an IgE-mediated hypersensitivity reaction, which leukocyte is
activated?. Answer: c.
Eosinophils
● During an IgE-mediated hypersensitivity reaction, the degranulation of
mast cells is a result of which receptor action?. Answer: Histamine
bound to H2
,● What characteristic do atopic individuals have that make them
genetically predisposed to develop allergies?. Answer: c.
Greater quantities of IgE
● What is the mechanism that results in type II hypersensitivity
reactions?. Answer: d.
Antibodies bind to the antigens on the cell surface.
● When mismatched blood is administered causing an ABO
incompatibility, the erythrocytes are destroyed by. Answer: a.
Complement-mediated cell lysis
● When antibodies are formed against red blood cell antigens of the Rh
system, the blood cells are destroyed by:. Answer: Phagocytosis in the
spleen
● When soluble antigens from infectious agents enter circulation, tissue
damage is a result of:. Answer: d.
Neutrophil granules and toxic oxygen products
● How are target cells destroyed in a type II hypersensitivity reaction?.
Answer: d.
Natural killer cells
,● Graves disease (hyperthyroidism) is an example of which type II
hypersensitivity reaction?. Answer: Modulation
● Type III hypersensitivity reactions are a result of which of the
following?. Answer: b.
Antibodies binding to soluble antigens that were released into body
fluids and the immune complexes being deposited in the tissues
● A type IV hypersensitivity reaction causes which result?. Answer: .
Lymphokine-producing Th1 cells directly attacking and destroying
cellular targets
● In a type III hypersensitivity reaction, the harmful effects after the
immune complexes that are deposited in tissues are a result of:. Answer:
Complement activation
● Raynaud phenomenon is classified as a type III hypersensitivity
reaction and is due to:. Answer: a.
Immune complexes that are deposited in capillary beds, blocking
circulation
● Deficiencies in which element can produce depression of both B- and
T-cell function?. Answer: Zinc
, ● When the maternal immune system becomes sensitized against
antigens expressed by the fetus, what reaction occurs?. Answer:
Alloimmunity
● Tissue damage caused by the deposition of circulating immune
complexes containing an antibody against the host DNA is the cause of
which disease?. Answer: Systemic lupus erythematosus
● Why does tissue damage occurs in acute rejection after organ
transplantation?. Answer: a.
Th1 cells release cytokines that activate infiltrating macrophages, and
cytotoxic T cells directly attack the endothelial cells of the transplanted
tissue.
● Which blood cell carries the carbohydrate antigens for blood type?.
Answer: Erythrocytes
● A person with type O blood is likely to have high titers of which anti-
antibodies?. Answer: A and B
● Which class of immunoglobulins forms isohemagglutinins?. Answer:
IgM
● Which component of the immune system is deficient in individuals
with infections caused by viruses, fungi, or yeast?. Answer: T cells
FULL SOLUTION GRADED A+
● A hypersensitivity reaction that produces an allergic response is
called:. Answer: Anaphylaxis
● The common hay fever allergy is expressed through a reaction that is
mediated by which class of immunoglobulins?. Answer: IgE
● Which type of antibody is involved in type I hypersensitivity
reaction?. Answer: IgE
● Blood transfusion reactions are an example of:. Answer: Alloimmunity
● During an IgE-mediated hypersensitivity reaction, which leukocyte is
activated?. Answer: c.
Eosinophils
● During an IgE-mediated hypersensitivity reaction, the degranulation of
mast cells is a result of which receptor action?. Answer: Histamine
bound to H2
,● What characteristic do atopic individuals have that make them
genetically predisposed to develop allergies?. Answer: c.
Greater quantities of IgE
● What is the mechanism that results in type II hypersensitivity
reactions?. Answer: d.
Antibodies bind to the antigens on the cell surface.
● When mismatched blood is administered causing an ABO
incompatibility, the erythrocytes are destroyed by. Answer: a.
Complement-mediated cell lysis
● When antibodies are formed against red blood cell antigens of the Rh
system, the blood cells are destroyed by:. Answer: Phagocytosis in the
spleen
● When soluble antigens from infectious agents enter circulation, tissue
damage is a result of:. Answer: d.
Neutrophil granules and toxic oxygen products
● How are target cells destroyed in a type II hypersensitivity reaction?.
Answer: d.
Natural killer cells
,● Graves disease (hyperthyroidism) is an example of which type II
hypersensitivity reaction?. Answer: Modulation
● Type III hypersensitivity reactions are a result of which of the
following?. Answer: b.
Antibodies binding to soluble antigens that were released into body
fluids and the immune complexes being deposited in the tissues
● A type IV hypersensitivity reaction causes which result?. Answer: .
Lymphokine-producing Th1 cells directly attacking and destroying
cellular targets
● In a type III hypersensitivity reaction, the harmful effects after the
immune complexes that are deposited in tissues are a result of:. Answer:
Complement activation
● Raynaud phenomenon is classified as a type III hypersensitivity
reaction and is due to:. Answer: a.
Immune complexes that are deposited in capillary beds, blocking
circulation
● Deficiencies in which element can produce depression of both B- and
T-cell function?. Answer: Zinc
, ● When the maternal immune system becomes sensitized against
antigens expressed by the fetus, what reaction occurs?. Answer:
Alloimmunity
● Tissue damage caused by the deposition of circulating immune
complexes containing an antibody against the host DNA is the cause of
which disease?. Answer: Systemic lupus erythematosus
● Why does tissue damage occurs in acute rejection after organ
transplantation?. Answer: a.
Th1 cells release cytokines that activate infiltrating macrophages, and
cytotoxic T cells directly attack the endothelial cells of the transplanted
tissue.
● Which blood cell carries the carbohydrate antigens for blood type?.
Answer: Erythrocytes
● A person with type O blood is likely to have high titers of which anti-
antibodies?. Answer: A and B
● Which class of immunoglobulins forms isohemagglutinins?. Answer:
IgM
● Which component of the immune system is deficient in individuals
with infections caused by viruses, fungi, or yeast?. Answer: T cells
