NR565 ADVANCED PHARMACOLOGY
MIDTERM EXAM STUDY GUIDE
QUESTIONS AND ANSWERS 100% PASS
2026 EDITION
Drugs that APRNs can prescribe - ANS Schedule 3-5 drugs
Determined by State Boards of Nursing, Medicine, and Pharmacy - ANS Prescriptive authority
regulation
Leads to fewer treatment options for patients, requiring them to find providers with authority -
ANS Limited prescriptive authority impact
Understanding prescribed drugs, their effects, contraindications, and ensuring correct dosages -
ANS Key responsibilities of prescribing
Acronym for CYP450 enzyme inducers: Barbiturates, St. John's Wort, Carbamazepine, Rifampin,
Alcohol, Phenytoin, Griseofulvin, Phenobarbital, Sulfonylureas - ANS BSCRAP GPS Incudes
Rage
Amount of active drug reaching systemic circulation from administration site -
ANS Bioavailability
1
@2026 EDITION ALLRIGHTS RESERVED
, Include forgetfulness, lack of planning, cost, dissatisfaction, and altered dosing - ANS Reasons
for medication nonadherence
Absorption is slow in neonates due to low muscle blood flow; absorption becomes rapid in early
infancy - ANS IM administration in neonates and infants
Gastric emptying time is prolonged and irregular in early infancy, affecting drug absorption -
ANS Oral administration in neonates/infants
Based on body surface area (BSA) calculation - ANS Dosage determination for pediatric
patients
Steps include defining the problem, setting therapeutic objectives, choosing treatment,
verifying its suitability, starting treatment, giving information, and monitoring treatment -
ANS Guiding principles for prescribers
Examples include Valproate, Isoniazid, Sulfonamides, Amiodarone, Chloramphenicol,
Ketoconazole, Grapefruit juice, Quinidine - ANS CYP450 inhibitors
Basis for prescribing decisions, considering drug interactions and effects on target receptors -
ANS Pharmacokinetics and pharmacodynamics
Tool identifying inappropriate medication use in older adults, cautioning against certain drugs
and interactions - ANS Beer's Criteria
Include adverse drug events, increased healthcare interactions, cognitive impairment, reduced
adherence, falls, and mortality - ANS Impacts of polypharmacy
They decrease medication metabolism - ANS CYP450 inhibitors function
May cause toxicity if enzymes are inactive or ineffectiveness if enzymes are overactive -
ANS CYP450 inhibitors consequences
2
@2026 EDITION ALLRIGHTS RESERVED
MIDTERM EXAM STUDY GUIDE
QUESTIONS AND ANSWERS 100% PASS
2026 EDITION
Drugs that APRNs can prescribe - ANS Schedule 3-5 drugs
Determined by State Boards of Nursing, Medicine, and Pharmacy - ANS Prescriptive authority
regulation
Leads to fewer treatment options for patients, requiring them to find providers with authority -
ANS Limited prescriptive authority impact
Understanding prescribed drugs, their effects, contraindications, and ensuring correct dosages -
ANS Key responsibilities of prescribing
Acronym for CYP450 enzyme inducers: Barbiturates, St. John's Wort, Carbamazepine, Rifampin,
Alcohol, Phenytoin, Griseofulvin, Phenobarbital, Sulfonylureas - ANS BSCRAP GPS Incudes
Rage
Amount of active drug reaching systemic circulation from administration site -
ANS Bioavailability
1
@2026 EDITION ALLRIGHTS RESERVED
, Include forgetfulness, lack of planning, cost, dissatisfaction, and altered dosing - ANS Reasons
for medication nonadherence
Absorption is slow in neonates due to low muscle blood flow; absorption becomes rapid in early
infancy - ANS IM administration in neonates and infants
Gastric emptying time is prolonged and irregular in early infancy, affecting drug absorption -
ANS Oral administration in neonates/infants
Based on body surface area (BSA) calculation - ANS Dosage determination for pediatric
patients
Steps include defining the problem, setting therapeutic objectives, choosing treatment,
verifying its suitability, starting treatment, giving information, and monitoring treatment -
ANS Guiding principles for prescribers
Examples include Valproate, Isoniazid, Sulfonamides, Amiodarone, Chloramphenicol,
Ketoconazole, Grapefruit juice, Quinidine - ANS CYP450 inhibitors
Basis for prescribing decisions, considering drug interactions and effects on target receptors -
ANS Pharmacokinetics and pharmacodynamics
Tool identifying inappropriate medication use in older adults, cautioning against certain drugs
and interactions - ANS Beer's Criteria
Include adverse drug events, increased healthcare interactions, cognitive impairment, reduced
adherence, falls, and mortality - ANS Impacts of polypharmacy
They decrease medication metabolism - ANS CYP450 inhibitors function
May cause toxicity if enzymes are inactive or ineffectiveness if enzymes are overactive -
ANS CYP450 inhibitors consequences
2
@2026 EDITION ALLRIGHTS RESERVED
