PNP301 TEST 3 QUESTIONS AND ANSWERS
/. Which of the following would result from a reduced number of erythrocytes in the
blood?
a. Increased hemoglobin in the blood
b. Decreased hematocrit
c. Increased risk of hemostasis
d. Decreased osmotic pressure of the blood - Answer-B. decreased hematocrit
/.What term is used to describe a deficit of all types of blood cells? - Answer-
Pancytopenia = decreased # of RBCs, WBCs + platelets
/.Chronic blood loss causes anemia because of the:
a. shortened life span of the erythrocytes.
b. lower metabolic rate.
c. loss of protein and electrolytes.
d. smaller amount of recycled iron available. - Answer-D. smaller amount of recycled
iron available
/.What is the etiology of sickle cell anemia? - Answer-a defective gene inherited from
both parents
/.Which of the following best describes the characteristic erythrocyte associated with
pernicious anemia?
a. Hypochromic, microcytic
b. Normochromic, normocytic
c. Elongated, sickle-shaped
d. Megaloblastic or macrocytic nucleated cells - Answer-D. MEGAloblastic or
MACROcytic nucleated cells
/.What causes numbness and tingling in the fingers of individuals with untreated
pernicious anemia?
a. Persistent hyperbilirubinemia
b. Increasing acidosis affecting metabolism
c. Vitamin B12 deficit causing peripheral nerve demyelination
d. Multiple small vascular occlusions affecting peripheral nerves - Answer-C. Vit. B12
deficit causing peripheral nerve demyelination
/.Jaundice is a typical sign of which type of anemia? - Answer-Sickle cell anemia
/.What are the typical early general signs and symptoms of anemia?
, a. Chest pain, palpitations
b. Jaundice, stomatitis
c. Pallor, dyspnea, and fatigue
d. Bradycardia, heat intolerance - Answer-C.
-Pallor
-Dyspnea
-Fatigue
/.What is the cause of oral ulcerations and delayed healing occurring with any severe
anemia?
a. Lack of folic acid for DNA synthesis
b. Frequent microinfarcts in the tissues
c. Deficit of oxygen for epithelial cell mitosis and metabolism
d. Elevated bilirubin levels in blood and body fluids - Answer-C. deficit of oxygen for
epthelial cell mitosis + metabolism
/.Hypochlorhydria (deficient stomach acid) is present in which type of anemia? -
Answer-pernicious (V.B12) anemia
/.Why is pernicious anemia treated with injections of vitamin B12?
a. An immune reaction in the stomach would destroy the vitamin.
b. Digestive enzymes would destroy the vitamin.
c. The vitamin irritates the gastric mucosa.
d. The ingested vitamin would not be absorbed into the blood. - Answer-D. the ingested
vitamin would not be absorbed into the blood.
/.Why do abnormally low hemoglobin values develop with pernicious anemia?
a. Decreased production of erythrocytes
b. Shorter life span of erythrocytes
c. Abnormal structure of hemoglobin chains
d. Deficit of folic acid - Answer-B. shorter lifespan of erythrocytes
/.What are the common early signs of aplastic anemia?
a. Painful joints and skeletal deformity
b. Abdominal discomfort and splenomegaly
c. Excessive bleeding and recurrent infections
d. Palpitations and chest pain - Answer-C. excessive bleeding and recurrent infections
/.Why do vascular occlusions and infarcts occur frequently with sickle cell anemia?
a. The red blood cells are abnormally large.
b. Increased hemolysis of erythrocytes occurs.
c. Erythrocytes change to sickle shape when hypoxia occurs.
d. HbS is unable to transport oxygen. - Answer-C. erythrocytes change to sickle shape
when hypoxia occurs
/.Which of the following applies to sickle cell trait?
/. Which of the following would result from a reduced number of erythrocytes in the
blood?
a. Increased hemoglobin in the blood
b. Decreased hematocrit
c. Increased risk of hemostasis
d. Decreased osmotic pressure of the blood - Answer-B. decreased hematocrit
/.What term is used to describe a deficit of all types of blood cells? - Answer-
Pancytopenia = decreased # of RBCs, WBCs + platelets
/.Chronic blood loss causes anemia because of the:
a. shortened life span of the erythrocytes.
b. lower metabolic rate.
c. loss of protein and electrolytes.
d. smaller amount of recycled iron available. - Answer-D. smaller amount of recycled
iron available
/.What is the etiology of sickle cell anemia? - Answer-a defective gene inherited from
both parents
/.Which of the following best describes the characteristic erythrocyte associated with
pernicious anemia?
a. Hypochromic, microcytic
b. Normochromic, normocytic
c. Elongated, sickle-shaped
d. Megaloblastic or macrocytic nucleated cells - Answer-D. MEGAloblastic or
MACROcytic nucleated cells
/.What causes numbness and tingling in the fingers of individuals with untreated
pernicious anemia?
a. Persistent hyperbilirubinemia
b. Increasing acidosis affecting metabolism
c. Vitamin B12 deficit causing peripheral nerve demyelination
d. Multiple small vascular occlusions affecting peripheral nerves - Answer-C. Vit. B12
deficit causing peripheral nerve demyelination
/.Jaundice is a typical sign of which type of anemia? - Answer-Sickle cell anemia
/.What are the typical early general signs and symptoms of anemia?
, a. Chest pain, palpitations
b. Jaundice, stomatitis
c. Pallor, dyspnea, and fatigue
d. Bradycardia, heat intolerance - Answer-C.
-Pallor
-Dyspnea
-Fatigue
/.What is the cause of oral ulcerations and delayed healing occurring with any severe
anemia?
a. Lack of folic acid for DNA synthesis
b. Frequent microinfarcts in the tissues
c. Deficit of oxygen for epithelial cell mitosis and metabolism
d. Elevated bilirubin levels in blood and body fluids - Answer-C. deficit of oxygen for
epthelial cell mitosis + metabolism
/.Hypochlorhydria (deficient stomach acid) is present in which type of anemia? -
Answer-pernicious (V.B12) anemia
/.Why is pernicious anemia treated with injections of vitamin B12?
a. An immune reaction in the stomach would destroy the vitamin.
b. Digestive enzymes would destroy the vitamin.
c. The vitamin irritates the gastric mucosa.
d. The ingested vitamin would not be absorbed into the blood. - Answer-D. the ingested
vitamin would not be absorbed into the blood.
/.Why do abnormally low hemoglobin values develop with pernicious anemia?
a. Decreased production of erythrocytes
b. Shorter life span of erythrocytes
c. Abnormal structure of hemoglobin chains
d. Deficit of folic acid - Answer-B. shorter lifespan of erythrocytes
/.What are the common early signs of aplastic anemia?
a. Painful joints and skeletal deformity
b. Abdominal discomfort and splenomegaly
c. Excessive bleeding and recurrent infections
d. Palpitations and chest pain - Answer-C. excessive bleeding and recurrent infections
/.Why do vascular occlusions and infarcts occur frequently with sickle cell anemia?
a. The red blood cells are abnormally large.
b. Increased hemolysis of erythrocytes occurs.
c. Erythrocytes change to sickle shape when hypoxia occurs.
d. HbS is unable to transport oxygen. - Answer-C. erythrocytes change to sickle shape
when hypoxia occurs
/.Which of the following applies to sickle cell trait?
