NUR 334 pharm exam 2 Questions
|| || || || || ||
with answers || ||
what drug class does gentamicin belong to?
|| || || || || ||
Aminoglycosides
What is the indicated use of aminoglycosides?
|| || || || || ||
- Treat severe infections of the abdomen and urinary
|| || || || || || || || ||
tract, hospital acquired pneumonia, bacteremia, and
|| || || || || ||
endocarditis
- serious gram-negative bacterial infections and
|| || || || || ||
infections caused by staphylococci when penicillins or
|| || || || || || ||
other less toxic drugs are contraindicated
|| || || || ||
Which antibiotics inhibit protein synthesis?
|| || || ||
tetracyclines, macrolides, aminoglycosides || ||
what are the pharmacokinetics of gentamicin?
|| || || || ||
- absorption: well absorbed IM and IV
|| || || || || ||
,- distribution: widely distributed in extracellular fluid,
|| || || || || || ||
cross placenta, small amount enters breast milk, poor
|| || || || || || || ||
penetration into CSF || ||
- metabolism and excretion: >90% renal
|| || || || ||
- half life: 2-4 hr or longer in renal impairment
|| || || || || || || || ||
What drugs fall into the aminoglycoside drug class?
|| || || || || || ||
gentamicin, streptomycin, amikacin, neomycin,
|| || || ||
trobramicin
What are the most common side effects and adverse
|| || || || || || || || ||
effects of aminoglycosides (symptoms associated)?
|| || || ||
- ototoxicity: ringing in the ears
|| || || || ||
- anemia: fatigue, feeling cold, dizziness, pallor
|| || || || || ||
, - thrombocytopenia: excessive bruising, petechiae,
|| || || || ||
excessive bleeding ||
- nephrotoxicity: oliguria, edema, hypertension
|| || || ||
What is oliguria? || ||
-Less than 500 cc of urine in 24 hours
|| || || || || || || ||
-low urine output || ||
What is the concern when a patient is experiencing
|| || || || || || || || ||
oliguria?
- impaired renal function possibly due to nephrotoxicity
|| || || || || || || ||
of a med or illness
|| || || ||
- can alter the electrolyte balance and fluid balance of
|| || || || || || || || || ||
the body resulting in hypo/hypernatremia or
|| || || || ||
hypo/hyperkalemia
||
What is a broad spectrum antibiotic? || || || || ||
A drug effective against a wide variety of microbial
|| || || || || || || || ||
species
|| || || || || ||
with answers || ||
what drug class does gentamicin belong to?
|| || || || || ||
Aminoglycosides
What is the indicated use of aminoglycosides?
|| || || || || ||
- Treat severe infections of the abdomen and urinary
|| || || || || || || || ||
tract, hospital acquired pneumonia, bacteremia, and
|| || || || || ||
endocarditis
- serious gram-negative bacterial infections and
|| || || || || ||
infections caused by staphylococci when penicillins or
|| || || || || || ||
other less toxic drugs are contraindicated
|| || || || ||
Which antibiotics inhibit protein synthesis?
|| || || ||
tetracyclines, macrolides, aminoglycosides || ||
what are the pharmacokinetics of gentamicin?
|| || || || ||
- absorption: well absorbed IM and IV
|| || || || || ||
,- distribution: widely distributed in extracellular fluid,
|| || || || || || ||
cross placenta, small amount enters breast milk, poor
|| || || || || || || ||
penetration into CSF || ||
- metabolism and excretion: >90% renal
|| || || || ||
- half life: 2-4 hr or longer in renal impairment
|| || || || || || || || ||
What drugs fall into the aminoglycoside drug class?
|| || || || || || ||
gentamicin, streptomycin, amikacin, neomycin,
|| || || ||
trobramicin
What are the most common side effects and adverse
|| || || || || || || || ||
effects of aminoglycosides (symptoms associated)?
|| || || ||
- ototoxicity: ringing in the ears
|| || || || ||
- anemia: fatigue, feeling cold, dizziness, pallor
|| || || || || ||
, - thrombocytopenia: excessive bruising, petechiae,
|| || || || ||
excessive bleeding ||
- nephrotoxicity: oliguria, edema, hypertension
|| || || ||
What is oliguria? || ||
-Less than 500 cc of urine in 24 hours
|| || || || || || || ||
-low urine output || ||
What is the concern when a patient is experiencing
|| || || || || || || || ||
oliguria?
- impaired renal function possibly due to nephrotoxicity
|| || || || || || || ||
of a med or illness
|| || || ||
- can alter the electrolyte balance and fluid balance of
|| || || || || || || || || ||
the body resulting in hypo/hypernatremia or
|| || || || ||
hypo/hyperkalemia
||
What is a broad spectrum antibiotic? || || || || ||
A drug effective against a wide variety of microbial
|| || || || || || || || ||
species
