PANCE ENDOCRINOLOGY PREPARATION
TEST 2026 QUESTIONS AND CORRECT
ANSWERS GRADED A+
● what initial test do you order if you're concerned for acromegaly.
Answer: IGF-1
● what is the first line medical management for acromegaly. Answer:
octreotide or lanreotide
● what is a GH receptor antagonist that can be used in the treatment of
acromegaly. Answer: pegvisomant
● cortisol + aldosterone deficiency. Answer: primary adrenal
insufficiency
● mcc of primary adrenal insufficiency. Answer: autoimmune
● what test do you use for screening for primary adrenal insufficiency.
Answer: cosyntropin stimulation test
● elevated ACTH + decreased cortisol. Answer: primary adrenal
insufficiency
, ● decreased ACTH + decreased cortisol. Answer: secondary adrenal
insufficiency
● what antibodies are present in addison's disease. Answer: 21-
hydroxylase antibodies
● first line treatment for adrenal insufficiency. Answer: hydrocortisone
+fludorcortisone if primary
● what test is used to distinguish cushing disease from ectopic ACTH.
Answer: dexamethason suppression test
● what do you expect the sodium to be in a pt with SIADH. Answer: low
(dilutional)
● what do you expect the sodium to be in a pt with DI. Answer: high
● treatment for SIADH. Answer: water and fluid restriction
● treatment for DI. Answer: desmopressin
TEST 2026 QUESTIONS AND CORRECT
ANSWERS GRADED A+
● what initial test do you order if you're concerned for acromegaly.
Answer: IGF-1
● what is the first line medical management for acromegaly. Answer:
octreotide or lanreotide
● what is a GH receptor antagonist that can be used in the treatment of
acromegaly. Answer: pegvisomant
● cortisol + aldosterone deficiency. Answer: primary adrenal
insufficiency
● mcc of primary adrenal insufficiency. Answer: autoimmune
● what test do you use for screening for primary adrenal insufficiency.
Answer: cosyntropin stimulation test
● elevated ACTH + decreased cortisol. Answer: primary adrenal
insufficiency
, ● decreased ACTH + decreased cortisol. Answer: secondary adrenal
insufficiency
● what antibodies are present in addison's disease. Answer: 21-
hydroxylase antibodies
● first line treatment for adrenal insufficiency. Answer: hydrocortisone
+fludorcortisone if primary
● what test is used to distinguish cushing disease from ectopic ACTH.
Answer: dexamethason suppression test
● what do you expect the sodium to be in a pt with SIADH. Answer: low
(dilutional)
● what do you expect the sodium to be in a pt with DI. Answer: high
● treatment for SIADH. Answer: water and fluid restriction
● treatment for DI. Answer: desmopressin