QUESTIONS AND 100% VERIFIED ANSWERS
WITH RATIONALES GRADED A+ LATEST
SOUTH UNIVERSITY
1.
A 52-year-old male presents with progressive exertional dyspnea and bilateral
ankle edema. Physical examination reveals an S3 gallop and bibasilar crackles.
Which medication provides both mortality reduction and symptom improvement?
A. Furosemide
B. Metoprolol succinate
C. Digoxin
D. Amlodipine
Correct Answer: B
Rationale: Evidence-based beta-blockers such as metoprolol succinate reduce
mortality and hospitalizations in heart failure with reduced ejection fraction.
Diuretics relieve symptoms but do not improve survival.
2.
A 24-year-old woman presents with dysuria and urinary frequency. Urinalysis
reveals positive nitrites and leukocyte esterase. She has no drug allergies. First-line
therapy is:
A. Ciprofloxacin
B. Trimethoprim-sulfamethoxazole for 10 days
C. Nitrofurantoin
D. Amoxicillin-clavulanate
Correct Answer: C
,Rationale: Nitrofurantoin is first-line for uncomplicated cystitis due to
effectiveness and low resistance rates. Fluoroquinolones are reserved for
complicated infections.
3.
A patient with type 2 diabetes has an A1C of 8.9% despite maximum-dose
metformin. Which agent provides cardiovascular benefit?
A. Sitagliptin
B. Glyburide
C. Empagliflozin
D. Acarbose
Correct Answer: C
Rationale: SGLT2 inhibitors such as empagliflozin reduce cardiovascular events
and slow progression of diabetic nephropathy.
4.
A 6-year-old child presents with fever, sore throat, and strawberry tongue. Rapid
antigen detection test is positive. Appropriate management includes:
A. Azithromycin for 3 days
B. Amoxicillin
C. No treatment
D. Prednisone
Correct Answer: B
Rationale: Group A streptococcal pharyngitis requires beta-lactam therapy to
prevent rheumatic fever.
,5.
Which finding most strongly supports a diagnosis of bacterial pneumonia rather
than viral?
A. Wheezing
B. Gradual onset
C. Lobar consolidation on imaging
D. Low-grade fever
Correct Answer: C
Rationale: Lobar consolidation is characteristic of bacterial pneumonia, whereas
viral infections often produce diffuse interstitial patterns.
6.
A patient taking lisinopril develops facial swelling and difficulty breathing. The
most appropriate action is:
A. Reduce dose
B. Add antihistamine
C. Discontinue lisinopril immediately
D. Switch to another ACE inhibitor
Correct Answer: C
Rationale: Angioedema is a life-threatening adverse effect of ACE inhibitors and
requires immediate discontinuation.
7.
A 34-year-old woman presents with irregular menses, hirsutism, and obesity. Most
likely diagnosis?
A. Hypothyroidism
B. Cushing syndrome
C. Polycystic ovary syndrome
D. Premature ovarian failure
, Correct Answer: C
Rationale: PCOS presents with hyperandrogenism, ovulatory dysfunction, and
insulin resistance.
8.
Which immunization is contraindicated during pregnancy?
A. Tdap
B. Influenza (inactivated)
C. MMR
D. Hepatitis B
Correct Answer: C
Rationale: Live vaccines such as MMR are contraindicated during pregnancy.
9.
A 68-year-old with atrial fibrillation has a CHA₂DS₂-VASc score of 3.
Recommended management includes:
A. Aspirin only
B. No anticoagulation
C. Oral anticoagulation
D. Rate control only
Correct Answer: C
Rationale: A score ≥2 in men or ≥3 in women indicates need for anticoagulation
to reduce stroke risk.
10.
Which thyroid lab pattern indicates primary hypothyroidism?
A. Low TSH, high T4
B. High TSH, low T4