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by RebeccaTuckerAllChapter1-56Complete
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, Chapter 1: Introduction to Drugs ft ft ft ft
Format:MultipleChoice ft ft
Chapter:1
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ClientNeeds:PhysiologicalIntegrity:Pharmacologicaland
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fParenteralTherapies
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CognitiveLevel:Analyze ft ft
Difficulty:Moderate
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IntegratedProcess:NursingProcess Objective: ft ft ft f t
1
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PageandHeader:3,Introduction
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A nurse working in radiology administers iodine to a patient who is having a computed tomography
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(CT)scan. The nurse working on the oncology unit administers chemotherapy to patients
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who have cancer. At the Public Health Department, a nurse administers a measles-mumps-
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rubella (MMR) vaccine to a 14-month-old child as a routine immunization. Which branch of ft ft ft ft ft ft ft ft ft ft f t ft ft
pharmacology best describes the actions of all three nurses?
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Pharmacoeconomics
f t Pharmacotherapeut
i cs f t
Pharmacodynamics
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f t Pharmacokinetics
f t Ans: B
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Pharmacology is the study of the biologic effects of chemicals. Nurses are involved with clinical ft ft ft ft ft ft ft ft ft ft ft ft ft ft
fpharmacology or pharmacotherapeutics, which is a branch of pharmacology that deals with the
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f uses ofdrugs to treat, prevent, and diagnose disease. The radiology nurse is administering a drug
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fto help diagnose a disease. The oncology nurse is administering a drug to help treat a disease.
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Pharmacoeconomics includes any costs involved in drug therapy. Pharmacodynamics involves ft ft ft ft ft ft ft ft ft
fhow adrug affects the body and pharmacokinetics is how the body acts on the body.
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A physician has ordered intramuscular (IM) injections of morphine, a narcotic, every 4 hours as
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needed forpain in a motor vehicle accident victim. The nurse is aware this drug has a high
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abuse potential. f t ft
Under what category would morphine be classified? ft ft ft ft ft ft
Schedule I ft
,Schedule II ft
f t Schedule III ft
f t Schedule IV ft
f t Ans: B
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Narcotics with a high abuse potential are classified as Schedule II drugs because of severe dependence
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f liability. Schedule I drugs have high abuse potential and no accepted medical use. Schedule III
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drugshave a lesser abuse potential than II and an accepted medical use. Schedule IV
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drugs have low abusepotential and limited dependence liability.
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When involved in phase III drug evaluation studies, what responsibilities would the nurse
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f t have?Working with animals who are given experimental drugs ft ft ft ft ft ft ft
Choosing appropriate patients to be involved in the drug study
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f t Monitoring and observing patients closely for adverse effects
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f t Conducting research to determine effectiveness of the drug Ans:
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f t C
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Phase III studies involve use of a drug in a vast clinical population in which patients are asked to
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recordany symptoms they experience while taking the drugs. Nurses may be responsible for
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f helping collect and analyze the information to be shared with the Food and Drug Administration
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f(FDA) but would not conduct research independently because nurses do not prescribe
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fmedications. Use of animals in drug testing is done in the preclinical trials. Select patients who
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f are involved in phase II studies to participatein studies where the participants have the disease
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f the drug is intended to treat. These patients are monitored closely for drug action and adverse
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feffects. Phase I studies involve healthy human volunteerswho are usually paid for their
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f participation. Nurses may observe for adverse effects and toxicity.
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What concept is considered when generic drugs are substituted for brand name
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f t drugs?Bioavailability
Critical
f t concentration
, Distribution
f t Half-life
f t Ans: A
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Bioavailability is the portion of a dose of a drug that reaches the systemic circulation and is ft ft ft ft ft ft ft ft ft ft ft ft ft ft ft ft
f available to act on body cells. Binders used in a generic drug may not be the same as those used
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in the brand name drug. Therefore, the way the body breaks down and uses the drug may differ,
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which may eliminate a generic drug substitution. Critical concentration is the amount of a drug
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that is needed to cause a therapeutic effect and should not differ between generic and brand
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f name medications. Distribution is the phase of pharmacokinetics, which involves the movement
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f of a drug to the body’s tissues and is the
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same in generic and brand name drugs. A drug’s half-life is the time it takes for the amount of
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drug todecrease to half the peak level, which should not change when substituting a generic
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fmedication.
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A nurse is assessing the patient’s home medication use. After listening to the patient list current
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medications, the nurse asks what priority question?
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Do you take any generic medications?
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Are any of these medications orphan drugs?
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f t Are these medications safe to take during
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f t pregnancy?Do you take any over-the-counter ft ft ft ft
f t medications?
Ans: D
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It is important for the nurse to specifically question use of over-the-counter medications because
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f patients may not consider them important. The patient is unlikely to know the meaning of
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f orphan drugsunless they too are health care providers. Safety during pregnancy, use of a generic
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f medication, or classification of orphan drugs are things the patient would be unable to answer
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f but could be found in reference books if the nurse wishes to research them.
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After completing a course on pharmacology for nurses, what will the nurse
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f t know?Everything necessary for safe and effective medication administration ft ft ft ft ft ft ft
f t Current pharmacologic therapy; the nurse will not require ongoing education for 5
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