RN HESI
Pharmacology
V2 (2026) – Practice Exam with Rationales
– HESI RN Pharmacology Study Material
, 1
RN HESI Pharmacology V2 (2026) –
Practice Exam with Rationales – HESI RN
Pharmacology Study Material
1.The nurse reviews the new prescription, phenelzine (Nardil),
a monoamine oxidase inhibitor (MAOI), for a client with
depression on the psychiatric unit. Which information is most
important for the nurse to assess?
A. Consumption of any alcohol or tyramine rich foods
B. Reports of nausea or vomiting
C. Therapeutic serum drug levels
D. Blood pressure and pulse prior to taking each dose
- correct answer-A
2.The nurse is administering haloperidol 0.5 mg IM PRN to a
client for the first time. What side effects should the nurse
assess thr client during the initial dose?
A. Bradykinesia
B. Dystonia
C. Somatization
D. Akathisia
- correct answer-B
3.While reviewing the client's electronic medical record (EMR),
the nurse assesses a client who is at risk for a possible
interaction with an over-the-counter (OTC) decongestant.
Which client health history should the nurse report to the health
care provider concerning the OTC medication? (Select all that
apply)
A. Type 1 diabetes mellitus (DM)
B. Closed angle glaucome
C. Chronic hypertension
D. Rheumatoid arthritis
1
, 2
E. Crohn's disease
- correct answer-B,C
4.A client prescribed ipratropium reports nausea, blurred vision,
headaches, and insomnia after using the inhaler. Which action
should the nurse implement first?
A. Withhold the medication and report symptoms and vital signs
to the healthcare provider
B. Give PRN medication for nausea and vomiting and evaluate
client in 30 minutes
C. reassure client that the ipratropium given will alleviate the
symptoms
D. Delay administration of ipratropium until the next
maintenance medication is scheduled
- correct answer-A
5.A client diagnosed with multiple sclerosis is experiencing
profound weakness, blurry vision, and shooting pains in both
legs. Which medication is considered the best course of
treatment for the nurse to administer?
A. High dose methylprednisolone intravenously
B. Baclofen three times a day
C. Broad spectrum antibiotic coverage orally
D. Immunomodulatory drug therapy periodically
- correct answer-A
6.The nurse administers 30 mL of lactulose for a client with
stage 2 hepatic encephalopathy. Which assessment finding
would indicate the medication is being therapeutic?
A. A decrease in blood ammonia levels
B. A softening in the stools
C. An increase in glucose absorption
D. A suppression of gut acidification
- correct answer-A
2
Pharmacology
V2 (2026) – Practice Exam with Rationales
– HESI RN Pharmacology Study Material
, 1
RN HESI Pharmacology V2 (2026) –
Practice Exam with Rationales – HESI RN
Pharmacology Study Material
1.The nurse reviews the new prescription, phenelzine (Nardil),
a monoamine oxidase inhibitor (MAOI), for a client with
depression on the psychiatric unit. Which information is most
important for the nurse to assess?
A. Consumption of any alcohol or tyramine rich foods
B. Reports of nausea or vomiting
C. Therapeutic serum drug levels
D. Blood pressure and pulse prior to taking each dose
- correct answer-A
2.The nurse is administering haloperidol 0.5 mg IM PRN to a
client for the first time. What side effects should the nurse
assess thr client during the initial dose?
A. Bradykinesia
B. Dystonia
C. Somatization
D. Akathisia
- correct answer-B
3.While reviewing the client's electronic medical record (EMR),
the nurse assesses a client who is at risk for a possible
interaction with an over-the-counter (OTC) decongestant.
Which client health history should the nurse report to the health
care provider concerning the OTC medication? (Select all that
apply)
A. Type 1 diabetes mellitus (DM)
B. Closed angle glaucome
C. Chronic hypertension
D. Rheumatoid arthritis
1
, 2
E. Crohn's disease
- correct answer-B,C
4.A client prescribed ipratropium reports nausea, blurred vision,
headaches, and insomnia after using the inhaler. Which action
should the nurse implement first?
A. Withhold the medication and report symptoms and vital signs
to the healthcare provider
B. Give PRN medication for nausea and vomiting and evaluate
client in 30 minutes
C. reassure client that the ipratropium given will alleviate the
symptoms
D. Delay administration of ipratropium until the next
maintenance medication is scheduled
- correct answer-A
5.A client diagnosed with multiple sclerosis is experiencing
profound weakness, blurry vision, and shooting pains in both
legs. Which medication is considered the best course of
treatment for the nurse to administer?
A. High dose methylprednisolone intravenously
B. Baclofen three times a day
C. Broad spectrum antibiotic coverage orally
D. Immunomodulatory drug therapy periodically
- correct answer-A
6.The nurse administers 30 mL of lactulose for a client with
stage 2 hepatic encephalopathy. Which assessment finding
would indicate the medication is being therapeutic?
A. A decrease in blood ammonia levels
B. A softening in the stools
C. An increase in glucose absorption
D. A suppression of gut acidification
- correct answer-A
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