How many DSM V criteria for mania must be present to diagnose a manic episode?
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Three or more
What role do genetic factors play in Bipolar disorder?
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Increased risk by up to 24x that first degree relatives of
people with bipolar 1 will also have bipolar 1
,Why is it important to differentiate between bipolar disorders and borderline
personality disorder (BPD)?
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Bipolar disorders: Mainstay of treatment is pharmacology (although therapy
may also be helpful)
BPD: Medications tend to be ineffective. Therapy (e.g. DBT) is the most
effective treatment.
Why is Valproate contraindicated in children under age 2?
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Risk of severe liver failure (rare, but often fatal)
Valproate is rarely used under age 10, except when
monitored by experts
Newly diagnosed mania is uncommon in which populations?
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Children and adults over age 65
,What is the most common reason patients stop taking medications for bipolar
disorder?
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Unwanted side effects:
Sedation
Cognitive impairment
Weight gain
Rash
Tremor
Lamotrigine (Lamictal) is used off-label for what type of pain?
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Neuropathic and/or chronic pain
If your patient taking Lithium developed a tremor, what would you want to check?
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, Lithium level.
This may indicate toxicity.
How can the risk of any rash be minimized when starting Lamotrigine (Lamictal)?
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Very slow taper up over 6 weeks.
Which mood stabilizer may be effective in bipolar disorder with rapid cycling?
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Valproic Acid (Depakote)
What can be done to minimize sedation related to Valproate?
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Give this one a try later!
Three or more
What role do genetic factors play in Bipolar disorder?
Give this one a try later!
Increased risk by up to 24x that first degree relatives of
people with bipolar 1 will also have bipolar 1
,Why is it important to differentiate between bipolar disorders and borderline
personality disorder (BPD)?
Give this one a try later!
Bipolar disorders: Mainstay of treatment is pharmacology (although therapy
may also be helpful)
BPD: Medications tend to be ineffective. Therapy (e.g. DBT) is the most
effective treatment.
Why is Valproate contraindicated in children under age 2?
Give this one a try later!
Risk of severe liver failure (rare, but often fatal)
Valproate is rarely used under age 10, except when
monitored by experts
Newly diagnosed mania is uncommon in which populations?
Give this one a try later!
Children and adults over age 65
,What is the most common reason patients stop taking medications for bipolar
disorder?
Give this one a try later!
Unwanted side effects:
Sedation
Cognitive impairment
Weight gain
Rash
Tremor
Lamotrigine (Lamictal) is used off-label for what type of pain?
Give this one a try later!
Neuropathic and/or chronic pain
If your patient taking Lithium developed a tremor, what would you want to check?
Give this one a try later!
, Lithium level.
This may indicate toxicity.
How can the risk of any rash be minimized when starting Lamotrigine (Lamictal)?
Give this one a try later!
Very slow taper up over 6 weeks.
Which mood stabilizer may be effective in bipolar disorder with rapid cycling?
Give this one a try later!
Valproic Acid (Depakote)
What can be done to minimize sedation related to Valproate?
Give this one a try later!
