PHARMACOLOGY A PATIENT CENTERED
NURSING PROCESS APPROACH 401 ACTUAL
TEST PAPER 2026 COMPLETE QUESTIONS AND
ANSWERS GRADED A+
◉ Absorption. Answer: the movement of the drug into the
bloodstream after administration
◉ Bioavailability. Answer: percentage of administered drug available
for activity
◉ First Pass Effect (Metabolism). Answer: some drugs are
metabolized to an inactive form and are excreted, thus reducing the
amount of active drug available to exert a pharmacologic effect
◉ Distribution. Answer: movement of the drug from the circulation
to body tissues
◉ Distribution is affected by. Answer: Blood flow to tissues
Faster: heart , liver, kidneys, and brain
Slower: muscle, skin, and fat
, ◉ blood-brain barrier. Answer: limits and slows effect
lipid soluble meds can pass
◉ Protein binding of drugs. Answer: binds with most protein
(albumin)
◉ Drug-Drug interactions. Answer: 2 meds are trying to be bound
one will not be as bound as the other so it will have less effect and
there is a risk of toxicity
◉ Metabolism. Answer: the process by which the body chemically
changes drugs into a form that can be excreted
◉ P-450 enzyme. Answer: helps break down the med and evacuate
◉ Grapefruit juice. Answer: tastes like crap but also inhibits P-450
◉ Phenytoin. Answer: is a P-450 inducer
◉ Factors that decrease metabolism. Answer: cardiovascular
dysfunction (poor diffusion)
renal insufficiency (can't secrete)
starvation (no protein)
NURSING PROCESS APPROACH 401 ACTUAL
TEST PAPER 2026 COMPLETE QUESTIONS AND
ANSWERS GRADED A+
◉ Absorption. Answer: the movement of the drug into the
bloodstream after administration
◉ Bioavailability. Answer: percentage of administered drug available
for activity
◉ First Pass Effect (Metabolism). Answer: some drugs are
metabolized to an inactive form and are excreted, thus reducing the
amount of active drug available to exert a pharmacologic effect
◉ Distribution. Answer: movement of the drug from the circulation
to body tissues
◉ Distribution is affected by. Answer: Blood flow to tissues
Faster: heart , liver, kidneys, and brain
Slower: muscle, skin, and fat
, ◉ blood-brain barrier. Answer: limits and slows effect
lipid soluble meds can pass
◉ Protein binding of drugs. Answer: binds with most protein
(albumin)
◉ Drug-Drug interactions. Answer: 2 meds are trying to be bound
one will not be as bound as the other so it will have less effect and
there is a risk of toxicity
◉ Metabolism. Answer: the process by which the body chemically
changes drugs into a form that can be excreted
◉ P-450 enzyme. Answer: helps break down the med and evacuate
◉ Grapefruit juice. Answer: tastes like crap but also inhibits P-450
◉ Phenytoin. Answer: is a P-450 inducer
◉ Factors that decrease metabolism. Answer: cardiovascular
dysfunction (poor diffusion)
renal insufficiency (can't secrete)
starvation (no protein)
