NURS 8024 PHARM EXAM 3
ANTIMICROBIAL PART 2 FULLY SOLVED
COMPREHENSIVE SCRIPT 2026 COMPLETE
QUESTIONS AND SOLUTIONS GRADED A+
⩥ Pharmacodynamics. Answer: what the drug does to the body
⩥ Toxicology. Answer: The undesirable effects of chemicals on living
systems
⩥ Pharmacotherapeutics. Answer: dynamic that achieves the desired
therapeutic effect of the drug without causing other undesirable effects
⩥ Legend drugs. Answer: another name for prescription drugs
⩥ Pharmacogenomics. Answer: the study of genetically determined
variations in the response to drugs
⩥ Pharmacologic Agonist. Answer: agent binds to and activates the
receptor - directly or indirectly causing an effect, full or partial agonists
,⩥ Pharmacological Antagonist. Answer: Agent binds to receptor-
completes with other molecules and prevents binding by other
molecules-it inhibits other molecules from binding
⩥ Pro-drug. Answer: An inactive percursor chemical-must be abosorbed
and distributed and converted to the active form of the drug by biologic
processes.
⩥ What is ADME?. Answer: Absorption
Distribution
Metabolism
Elimination
⩥ Absorption. Answer: entry of pharmacologic agent into plasma
⩥ Distribution. Answer: agent leaves the bloodstream and distributes to
interstitial and intracellular fluids
⩥ Metablosim. Answer: chemical processes that occur to make the drug
useful in the bloodstream--done by the liver, kidney, or other tissue
⩥ Ellimination. Answer: Leaving the body-via urine, bile, feces, lungs,
sweat, breast milk
, ⩥ 2 Major Administration Routes. Answer: 1. Enteral -most common,
easy, cheap-BUT drug absorption pathways can be complicated
2. Parenteral-IV, fast, more expensive, once in-cannot get back
⩥ Enteral drug administration. Answer: oral, sublingual, rectal
drug absorption pathways complicated
**First-pass metabolism can limit the amount of drug that enters
systemic circulation
influenced by food and other drugs
⩥ What is first pass metabolism?. Answer: The concentration of drug is
greatly reduced BEFORE reaching systemic circulation. This mainly
involves liver enzymes, but also includes gastric enzymes, gut wall
enzymes, and bacterial enzymes. Bioavaliability is reduced.
https://www.youtube.com/watch?v=BQQns7RAUzA
⩥ Parenteral drug administration. Answer: -IV, IM, SubQ
- More control over actual dose of drug
- Directly into systemic circulation-bypass first pass metabolism
- used for drugs poorly absorbed by GI
-Rapid onset of action
-Disadvantage: cannot take the drug back, infection risk
ANTIMICROBIAL PART 2 FULLY SOLVED
COMPREHENSIVE SCRIPT 2026 COMPLETE
QUESTIONS AND SOLUTIONS GRADED A+
⩥ Pharmacodynamics. Answer: what the drug does to the body
⩥ Toxicology. Answer: The undesirable effects of chemicals on living
systems
⩥ Pharmacotherapeutics. Answer: dynamic that achieves the desired
therapeutic effect of the drug without causing other undesirable effects
⩥ Legend drugs. Answer: another name for prescription drugs
⩥ Pharmacogenomics. Answer: the study of genetically determined
variations in the response to drugs
⩥ Pharmacologic Agonist. Answer: agent binds to and activates the
receptor - directly or indirectly causing an effect, full or partial agonists
,⩥ Pharmacological Antagonist. Answer: Agent binds to receptor-
completes with other molecules and prevents binding by other
molecules-it inhibits other molecules from binding
⩥ Pro-drug. Answer: An inactive percursor chemical-must be abosorbed
and distributed and converted to the active form of the drug by biologic
processes.
⩥ What is ADME?. Answer: Absorption
Distribution
Metabolism
Elimination
⩥ Absorption. Answer: entry of pharmacologic agent into plasma
⩥ Distribution. Answer: agent leaves the bloodstream and distributes to
interstitial and intracellular fluids
⩥ Metablosim. Answer: chemical processes that occur to make the drug
useful in the bloodstream--done by the liver, kidney, or other tissue
⩥ Ellimination. Answer: Leaving the body-via urine, bile, feces, lungs,
sweat, breast milk
, ⩥ 2 Major Administration Routes. Answer: 1. Enteral -most common,
easy, cheap-BUT drug absorption pathways can be complicated
2. Parenteral-IV, fast, more expensive, once in-cannot get back
⩥ Enteral drug administration. Answer: oral, sublingual, rectal
drug absorption pathways complicated
**First-pass metabolism can limit the amount of drug that enters
systemic circulation
influenced by food and other drugs
⩥ What is first pass metabolism?. Answer: The concentration of drug is
greatly reduced BEFORE reaching systemic circulation. This mainly
involves liver enzymes, but also includes gastric enzymes, gut wall
enzymes, and bacterial enzymes. Bioavaliability is reduced.
https://www.youtube.com/watch?v=BQQns7RAUzA
⩥ Parenteral drug administration. Answer: -IV, IM, SubQ
- More control over actual dose of drug
- Directly into systemic circulation-bypass first pass metabolism
- used for drugs poorly absorbed by GI
-Rapid onset of action
-Disadvantage: cannot take the drug back, infection risk
