CLINICOPATHOLOGIC FOUNDATIONS OF
MEDICINE 7TH EDITION ( WITH ANSWER
KEY)
LATEST UPDATED EXAMINATION STUDY
GUIDE 2023
GUARANTEED GRADE A+
Chapter=1:=Cell=Adaptation,=Injury=and=Death
=Ischemia=and=other=toxic=injuries=increase=the=accumulation=of=intracellular=calcium=as=a=resul
t
1. of:
A) release=of=stored=calcium=from=the=mitochondria.
B) improved=intracellular=volume=regulation.
C) decreased=influx=across=the=cell=membrane.
D) attraction=of=calcium=to=fatty=infiltrates.
The=patient=is=found=to=have=liver=disease,=resulting=in=the=removal=of=a=lobe=of=his=liver.
2. Adaptation=to=the=reduced=size=of=the=liver=leads=to=_ of=the=remaining=liver=cells.
A) metaplasia
B) organ=atrophy
C) compensatory=hyperplasia
,D) physiologic=hypertrophy
A=person=eating=peanuts=starts=choking=and=collapses.=His=airway=obstruction=is=partially=cl
eared,=but=he=remains=hypoxic=until=he=reaches=the=hospital.=The=prolonged=cell=hypoxia
3. caused=a=cerebral=infarction=and=resulting _=in=the=brain.
A) caspase=activation
B) coagulation=necrosis
C) rapid=phagocytosis
D) protein=p53=deficiency
Bacteria=and=viruses=cause=cell=damage=by ,=which=is=unique=from=the=intracellular
4. damage=caused=by=other=injurious=agents.
A) disrupting=the=sodium/potassium=ATPase=pump
B) interrupting=oxidative=metabolism=processes
C) replicating=and=producing=continued=injury
,TEST BANK FOR RUBIN’S PATHOLOGY: C
= = = = ==
LINICOPATHOLOGIC FOUNDATIONS OF = = ==
MEDICINE 7TH EDITION ( WITH ANSWER
= = = = = ==
KEY)
LATEST UPDATED EXAMINATION STUDY
= = = ==
GUIDE 2023 =
GUARANTEED GRADE A+ = =
D) decreasing=protein=synthesis=and=function
The=patient=has=a=prolonged=interruption=in=arterial=blood=flow=to=his=left=kidney,=causing
5. hypoxic=cell=injury=and=the=release=of=free=radicals.=Free=radicals=damage=cells=by:
A) destroying=phospholipids=in=the=cell=membrane.
B) altering=the=immune=response=of=the=cell.
C) disrupting=calcium=storage=in=the=cell.
D) inactivation=of=enzymes=and=mitochondria.
, TEST BANK FOR RUBIN’S PATHOLOGY: C
= = = = ==
LINICOPATHOLOGIC FOUNDATIONS OF = = ==
MEDICINE 7TH EDITION ( WITH ANSWER
= = = = = ==
KEY)
LATEST UPDATED EXAMINATION STUDY
= = = ==
GUIDE 2023 =
GUARANTEED GRADE A+ = =
6. Injured=cells=have=impaired=flow=of=substances=through=the=cell=membrane=as=a=result=of:
A) increased=fat=load.
B) altered=permeability.
C) altered=glucose=utilization.
D) increased=surface=receptors.
7. Reversible=adaptive=intracellular=responses=are=initiated=by:
A) stimulus=overload.
B) genetic=mutations.
C) chemical=messengers.
D) mitochondrial=DNA.
8. Injured=cells=become=very=swollen=as=a=result=of:
A) increased=cell=protein=synthesis.
B) altered=cell=volume=regulation.
C) passive=entry=of=potassium=into=the=cell.
D) bleb=formation=in=the=plasma=membrane.
A=diabetic=patient=has=impaired=sensation,=circulation,=and=oxygenation=of=his=feet.=He=step
s=on=a=piece=of=glass,=the=wound=does=not=heal,=and=the=area=tissue=becomes=necrotic.=The=
necrotic
9. cell=death=is= characterized=by:
A) rapid=apoptosis.
B) cellular=rupture.
C) shrinkage=and=collapse.
D) chronic=inflammation.
A=99-year-old=woman=has=experienced=the=decline=of=cell=function=associated=with=age.=A
10. group=of=theories= of=cellular=aging=focus=on=programmed:
A) changes=with=genetic=influences.
B) elimination=of=cell=receptor=sites.
C) insufficient=telomerase=enzyme.