MARYVILLE UNIVERSITY
PHARMACOLOGY NURS-615
EXAM 2
What is hypochlorhydria? - ANSWERS-A state in which production
of hydrochloric acid in gastric secretions is low or absent
What do "azole" anti-fungals require for absorption? - ANSWERS-
ACID
What should "azole" anti-fungals NOT be administered with? -
ANSWERS-H2 Blockers or Protein pump inhibitors
What type of anti-fungal is terbinafine and what is it used for? -
ANSWERS-An allylamine anti-fungal highly effective against
dermatophyte infections (not much against Candida)
What are the side effects of terbinafine? - ANSWERS-MANY side
effects; skin, GI, and liver toxicity (LFTs must be monitored)
What medications are used for parasitic worms and intestinal
parasites? - ANSWERS-mebendazole
agromectin
ivermectin
,What medications are used for scabies and lice? - ANSWERS-
Ivermectin and permethrin cream
What type of medication is metronidazole (Flagyl) and what are its
characteristics? - ANSWERS-1. Antibiotic and anti-protazoal
2. It is bacteriocidal and BROAD spectrum
What is metronidazole used for? - ANSWERS-PID, endocarditis,
bacterial vaginosis, giardiasis, trichomonad, amebiasis
What is the drug of choice for the first episode of mild-moderate C.
Diff? - ANSWERS-Metronidazole (Flagyl)
What should not be ingested with metronidazole (Flagyl)? -
ANSWERS-Alcohol -- causes a disulfiram-like reaction
What is a disulfiram-like reaction? - ANSWERS-N/V, flushing of
skin, tachycardia, SOB
How long should alcohol be avoided after metronidazole treatment? -
ANSWERS-At least 48 hours
Metronidazole inhibits liver metabolism of propylene glycol and
should not be used with what? - ANSWERS-Meds like Miralax and
E-Cigs; could also cause disulfiram-like reaction
, What type of medication is Linezolid? - ANSWERS-Oxazolidinone --
It is an antibiotic and an MAOI
What. should Linezolid not be used with? - ANSWERS-Not to be
used with other MAOIs, serotonergic drugs, or foods with tyramine
What does Linezolid do if used with Sudafed? - ANSWERS-Increases
blood pressure
Linezolid should not be given with what drugs due to risk of serotonin
syndrome? - ANSWERS-SSRIs, Demerol, and MAOIs
How does carbamazepine work? - ANSWERS-Works by decreasing
nerve impulses that cause seizures and pain
How often should carbamazepine lab values be monitored? What
labs? - ANSWERS-CBC q 3-4 months
What anti-seizure med auto induces metabolism? - ANSWERS-
Carbamazepine
What medication decreases the production of RBCs, WBCs, and
platelets? - ANSWERS-Carbamazepine
What is carbamazepine half-life? - ANSWERS-Single dose: 30 hours
Multiple dose: 15 hours
PHARMACOLOGY NURS-615
EXAM 2
What is hypochlorhydria? - ANSWERS-A state in which production
of hydrochloric acid in gastric secretions is low or absent
What do "azole" anti-fungals require for absorption? - ANSWERS-
ACID
What should "azole" anti-fungals NOT be administered with? -
ANSWERS-H2 Blockers or Protein pump inhibitors
What type of anti-fungal is terbinafine and what is it used for? -
ANSWERS-An allylamine anti-fungal highly effective against
dermatophyte infections (not much against Candida)
What are the side effects of terbinafine? - ANSWERS-MANY side
effects; skin, GI, and liver toxicity (LFTs must be monitored)
What medications are used for parasitic worms and intestinal
parasites? - ANSWERS-mebendazole
agromectin
ivermectin
,What medications are used for scabies and lice? - ANSWERS-
Ivermectin and permethrin cream
What type of medication is metronidazole (Flagyl) and what are its
characteristics? - ANSWERS-1. Antibiotic and anti-protazoal
2. It is bacteriocidal and BROAD spectrum
What is metronidazole used for? - ANSWERS-PID, endocarditis,
bacterial vaginosis, giardiasis, trichomonad, amebiasis
What is the drug of choice for the first episode of mild-moderate C.
Diff? - ANSWERS-Metronidazole (Flagyl)
What should not be ingested with metronidazole (Flagyl)? -
ANSWERS-Alcohol -- causes a disulfiram-like reaction
What is a disulfiram-like reaction? - ANSWERS-N/V, flushing of
skin, tachycardia, SOB
How long should alcohol be avoided after metronidazole treatment? -
ANSWERS-At least 48 hours
Metronidazole inhibits liver metabolism of propylene glycol and
should not be used with what? - ANSWERS-Meds like Miralax and
E-Cigs; could also cause disulfiram-like reaction
, What type of medication is Linezolid? - ANSWERS-Oxazolidinone --
It is an antibiotic and an MAOI
What. should Linezolid not be used with? - ANSWERS-Not to be
used with other MAOIs, serotonergic drugs, or foods with tyramine
What does Linezolid do if used with Sudafed? - ANSWERS-Increases
blood pressure
Linezolid should not be given with what drugs due to risk of serotonin
syndrome? - ANSWERS-SSRIs, Demerol, and MAOIs
How does carbamazepine work? - ANSWERS-Works by decreasing
nerve impulses that cause seizures and pain
How often should carbamazepine lab values be monitored? What
labs? - ANSWERS-CBC q 3-4 months
What anti-seizure med auto induces metabolism? - ANSWERS-
Carbamazepine
What medication decreases the production of RBCs, WBCs, and
platelets? - ANSWERS-Carbamazepine
What is carbamazepine half-life? - ANSWERS-Single dose: 30 hours
Multiple dose: 15 hours
