BLOCK 6 - QUIZ 6 CONTENT| TOP SCORES MADE SIMPLE
| TRUSTED TEST SOLUTIONS!
Bone marrow growth factors Answer: - G-CSF/GM-CSF
- IL-6
- VEGF
- Erythropoietin ("EPO")
- Thrombopoietin / IL-11
- G-CSF/GM-CSF
- IL-6
- VEGF
- Erythropoietin ("EPO")
- Thrombopoietin / IL-11 Answer: Bone marrow growth factors
Drugs used for:
- High-intensity chemotherapy
- Stem cell mobilization
- Radiation injury
- MDS Answer: - G-CSF 5 mcg/kg daily
- ilgrastim (Neupogen)
- Pegfilgrastim (Neulasta)
- G-CSF 5 mcg/kg daily
- ilgrastim (Neupogen)
- Pegfilgrastim (Neulasta)
Clinical uses Answer: - High-intensity chemotherapy
- Stem cell mobilization
- Radiation injury
- MDS
1
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,"Eaters" and "secretors" Professional phagocytes. Specific and nonspecific cytoplasmic
granules. Answer: Neutrophils
"Eaters" and "secretors" Phagocytosis. Produce inflammatory cytokines. Present
antigens to T-cell. Answer: Monocytes
T-cell: Cellular immunity, lymphokines. B-cell: Humoral immunity, Abs. Null cell: Virally
infected, tumor cells. Answer: Lymphocytes
Specialized cells. Large eosinophilic granules. Parasitic immunity, some infections.
Allergic diseases. Answer: Eosinophils
Specialized cells. Large basophilic granules. Parasitic immunity, some infections.
Allergic diseases. Answer: Basophils
Blast cell characteristics Answer: - Large nucleus
- High nuclear:cytoplasmic (N:C) ratio
- Scant cytoplasm
- Open chromatin
- Prominent nucleoli
- Large nucleus
- High nuclear:cytoplasmic (N:C) ratio
- Scant cytoplasm
- Open chromatin
- Prominent nucleoli
Chacteristics of? Answer: Blast cells
Blast cells are seen in which conditions? Answer: - Acute Leukemia
- Myelodysplatic syndrome
- Acute Leukemia
- Myelodysplatic syndrome
What cells are seen Answer: Blast cells
Hypoproduction in bone marrow Answer: Aplastic anemia, marrow infiltration, viral
suppression
Aplastic anemia, marrow infiltration, viral suppression
2
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,[Hypo/hyper]production in bone marrow Answer: Hypoproduction in bone marrow
Hyperproduction in bone marrow Answer: - Leukemia
- Myeloproliferative Disorder (MPD)
- Leukemia
- Myeloproliferative Disorder (MPD)
[Hypo/hyper]production in bone marrow Answer: Hyperproduction
Neutrophilia Answer: increase in neutrophils that causes acute inflammation, tissue
necrosis
- Infection (bacterial)
- Steroids
- Myeloproliferative Disorders (MPD)
increase in neutrophils that causes acute inflammation, tissue necrosis
- Infection (bacterial)
- Steroids
- Myeloproliferative Disorders (MPD) Answer: Neutrophilia
Lymphocytosis Answer: Increase in lymphocytes
- Infections (viral)
- Lymphoproliferative disorders
Increase in lymphocytes
- Infections (viral)
- Lymphoproliferative disorders Answer: Lymphocytosis
Eosinophilia Answer: increase in eosinophils
- Allergy, Asthma
- Parasitic infections
- Neoplasm-> Mast cell disorders
increase in eosinophils
- Allergy, Asthma
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, - Parasitic infections
- Neoplasm-> Mast cell disorders Answer: Eosinophilia
Splenectomy Answer: Excision of the spleen
- causes transient rise in all cell counts
Excision of the spleen
- causes transient rise in all cell counts Answer: Splenectomy
Neutrophil count > 1,500/uL Answer: Neutrophilia
Causes of eosinophilia Answer: - Allergic reactions, Asthma: Drugs, environment
- Parasites, especially in International travelers or Immigrants: Pneumocystis,
toxoplasmosis, malaria, schistosomiasis
- Malignancy: Classical Hodgkin lymphoma, Chronic Myelogenous Leukemia
- Adrenal insufficiency
- Allergic reactions, Asthma: Drugs, environment
- Parasites, especially in International travelers or Immigrants: Pneumocystis,
toxoplasmosis, malaria, schistosomiasis
- Malignancy: Classical Hodgkin lymphoma, Chronic Myelogenous Leukemia
- Adrenal insufficiency
What erythrocytes are elevated? Answer: Eosinophils
Absolute eosinophil count > 500/uL Answer: Eosinophilia
Absolute monocyte count > 800/uL Answer: Monocytosis
Acute Leukemia results in the increase of what type of cells Answer: Blast cells
Myelodysplastic Syndrome results in an increase of what type of cells Answer: Blast
cells
[Myelodysplastic Syndrome / Acute Leukemia] is caused by normal bone marrow
production rate with deficient product Answer: Myelodysplastic Syndrome
[Myelodysplastic Syndrome / Acute Leukemia] is caused by hyperproduction by bone
marrow Answer: Acute Leukemia
Inherited WBC disorders Answer: - Chronic granulomatous disease
- Chediak-Higashi
4
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| TRUSTED TEST SOLUTIONS!
Bone marrow growth factors Answer: - G-CSF/GM-CSF
- IL-6
- VEGF
- Erythropoietin ("EPO")
- Thrombopoietin / IL-11
- G-CSF/GM-CSF
- IL-6
- VEGF
- Erythropoietin ("EPO")
- Thrombopoietin / IL-11 Answer: Bone marrow growth factors
Drugs used for:
- High-intensity chemotherapy
- Stem cell mobilization
- Radiation injury
- MDS Answer: - G-CSF 5 mcg/kg daily
- ilgrastim (Neupogen)
- Pegfilgrastim (Neulasta)
- G-CSF 5 mcg/kg daily
- ilgrastim (Neupogen)
- Pegfilgrastim (Neulasta)
Clinical uses Answer: - High-intensity chemotherapy
- Stem cell mobilization
- Radiation injury
- MDS
1
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,"Eaters" and "secretors" Professional phagocytes. Specific and nonspecific cytoplasmic
granules. Answer: Neutrophils
"Eaters" and "secretors" Phagocytosis. Produce inflammatory cytokines. Present
antigens to T-cell. Answer: Monocytes
T-cell: Cellular immunity, lymphokines. B-cell: Humoral immunity, Abs. Null cell: Virally
infected, tumor cells. Answer: Lymphocytes
Specialized cells. Large eosinophilic granules. Parasitic immunity, some infections.
Allergic diseases. Answer: Eosinophils
Specialized cells. Large basophilic granules. Parasitic immunity, some infections.
Allergic diseases. Answer: Basophils
Blast cell characteristics Answer: - Large nucleus
- High nuclear:cytoplasmic (N:C) ratio
- Scant cytoplasm
- Open chromatin
- Prominent nucleoli
- Large nucleus
- High nuclear:cytoplasmic (N:C) ratio
- Scant cytoplasm
- Open chromatin
- Prominent nucleoli
Chacteristics of? Answer: Blast cells
Blast cells are seen in which conditions? Answer: - Acute Leukemia
- Myelodysplatic syndrome
- Acute Leukemia
- Myelodysplatic syndrome
What cells are seen Answer: Blast cells
Hypoproduction in bone marrow Answer: Aplastic anemia, marrow infiltration, viral
suppression
Aplastic anemia, marrow infiltration, viral suppression
2
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,[Hypo/hyper]production in bone marrow Answer: Hypoproduction in bone marrow
Hyperproduction in bone marrow Answer: - Leukemia
- Myeloproliferative Disorder (MPD)
- Leukemia
- Myeloproliferative Disorder (MPD)
[Hypo/hyper]production in bone marrow Answer: Hyperproduction
Neutrophilia Answer: increase in neutrophils that causes acute inflammation, tissue
necrosis
- Infection (bacterial)
- Steroids
- Myeloproliferative Disorders (MPD)
increase in neutrophils that causes acute inflammation, tissue necrosis
- Infection (bacterial)
- Steroids
- Myeloproliferative Disorders (MPD) Answer: Neutrophilia
Lymphocytosis Answer: Increase in lymphocytes
- Infections (viral)
- Lymphoproliferative disorders
Increase in lymphocytes
- Infections (viral)
- Lymphoproliferative disorders Answer: Lymphocytosis
Eosinophilia Answer: increase in eosinophils
- Allergy, Asthma
- Parasitic infections
- Neoplasm-> Mast cell disorders
increase in eosinophils
- Allergy, Asthma
3
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, - Parasitic infections
- Neoplasm-> Mast cell disorders Answer: Eosinophilia
Splenectomy Answer: Excision of the spleen
- causes transient rise in all cell counts
Excision of the spleen
- causes transient rise in all cell counts Answer: Splenectomy
Neutrophil count > 1,500/uL Answer: Neutrophilia
Causes of eosinophilia Answer: - Allergic reactions, Asthma: Drugs, environment
- Parasites, especially in International travelers or Immigrants: Pneumocystis,
toxoplasmosis, malaria, schistosomiasis
- Malignancy: Classical Hodgkin lymphoma, Chronic Myelogenous Leukemia
- Adrenal insufficiency
- Allergic reactions, Asthma: Drugs, environment
- Parasites, especially in International travelers or Immigrants: Pneumocystis,
toxoplasmosis, malaria, schistosomiasis
- Malignancy: Classical Hodgkin lymphoma, Chronic Myelogenous Leukemia
- Adrenal insufficiency
What erythrocytes are elevated? Answer: Eosinophils
Absolute eosinophil count > 500/uL Answer: Eosinophilia
Absolute monocyte count > 800/uL Answer: Monocytosis
Acute Leukemia results in the increase of what type of cells Answer: Blast cells
Myelodysplastic Syndrome results in an increase of what type of cells Answer: Blast
cells
[Myelodysplastic Syndrome / Acute Leukemia] is caused by normal bone marrow
production rate with deficient product Answer: Myelodysplastic Syndrome
[Myelodysplastic Syndrome / Acute Leukemia] is caused by hyperproduction by bone
marrow Answer: Acute Leukemia
Inherited WBC disorders Answer: - Chronic granulomatous disease
- Chediak-Higashi
4
APPHIA - Crafted with Care and Precision for Academic Excellence.