BLOCK 7 - QUIZ 3 CONTENT| TOP SCORES MADE SIMPLE
| TRUSTED TEST SOLUTIONS!
Common causes of Acute Pancreatitis Answer: - Gallstones
- Alcohol
- Hypertriglyceridemia
- Endoscopic retrograde cholangiopancreatography (ERCP)
- Trauma
- Postoperative
- Drugs
- Sphincter of Oddi dysfunction
Acute Pancreatitis that is mild and self-limited Answer: Interstitial pancreatitis
Acute Pancreatitis in which there is pancreatic necrosis and may correlate with the
severity of clinical manifestations Answer: Necrotizing pancreatitis
- Gallstones
- Alcohol
- Hypertriglyceridemia
- Endoscopic retrograde cholangiopancreatography (ERCP)
- Trauma
- Postoperative
- Drugs
- Sphincter of Oddi dysfunction
Common causes of? Answer: Acute Pancreatitis
Phases of acute Pancreatitis Answer: - Initial Phase: Intra pancreatic digestive enzyme
activation and acinar cell injury
- Second phase: activation, chemo attraction, sequestration of neutrophils -> intra
pancreatic inflammation
1
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,- Third phase: due to the effects on the distant organs of activated proteolytic enzymes
and cytokines -> proteolysis, edema, interstitial hemorrhage, vascular damage, coag
necrosis
Acute Pancreatitis clinical manifestations Answer: Abdominal pain located in the
epigastrium and periumbilical region and often radiates to the back as well as to the
chest, flanks, and lower abdomen
- More intense when the patient is supine
What causes abdominal pain located in the epigastrium and periumbilical region and
often radiates to the back as well as to the chest, flanks, and lower abdomen
- More intense when the patient is supine Answer: Acute Pancreatitis
Gray Turner's sign Answer: Bruising of the flanks
- Seen in acute pancreatitis
Bruising of the flanks Answer: Gray Turner's sign
- Seen in acute pancreatitis
Acute pancreatitis physical findings Answer: - Gray Turner's sign - Bruising of the flanks
- Cullen's sign - Bruising and edema around umbilicus
Gray Turner's sign and Cullen's sign are seen in? Answer: Acute pancreatitis
Cullen's sign Answer: Bruising and edema around umbilicus
- Seen in acute pancreatitis
Bruising and edema around umbilicus Answer: Cullen's sign
- Seen in acute pancreatitis
Acute Pancreatitis lab findings Answer: - Elevated Amylase and Lipase
- Leukocytosis
- Hyperglycemia
- Hypocalcemia
- Hyperbilirubinemia
Elevated Amylase and Lipase Answer: Acute Pancreatitis l
- Elevated Amylase and Lipase
- Leukocytosis
2
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,- Hyperglycemia
- Hypocalcemia
- Hyperbilirubinemia
Lab findings of? Answer: Acute Pancreatitis
Markers of acute pancreatitis severity Answer: - Hemo concentration (Hct >44%)
- Age >60 years
- Blood urea nitrogen (BUN) >25 mg/dl
What hemo concentration is considered severe in acute pancreatitis Answer: Hct >44%
What BUN concentration is considered severe in acute pancreatitis Answer: >25 mg/dl
Acute Pancreatitis diagnosis Answer: - Typical abdominal pain
- Threefold or greater elevation in serum amylase and/or lipase level,
- Confirmatory findings on cross-sectional
abdominal imaging
Mild Acute Pancreatitis treatment Answer: Suupportive care
- clear liquid diet or low-fat solid diet
Severe Acute Pancreatitis treatment Answer: - Vigorous fluid resuscitation
- Measurement of hematocrit and BUN every 12 hours
- Enteral nutrition to prevent infectious complications
- Nasogastric delivery and nasojejunal delivery
Chronic Pancreatitis Answer: Irreversible damage to the pancreas as distinct from the
reversible changes noted in acute pancreatitis
Histologic abnormalities in chronic pancreatitis Answer: - chronic inflammation
- fibrosis
- progressive destruction of both exocrine and eventually
endocrine tissue
Pancreatitis with:
- chronic inflammation
3
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, - fibrosis
- progressive destruction of both exocrine and eventually
endocrine tissue Answer: Chronic pancreatitis
Types of Chronic Pancreatitis Answer: - Toxic-metabolic
- Idiopathic
- Generic
- Autoimmune
- Recurrent and Severe Acute Pancreatitis
- Obstructive
(TIGAR-O)
- Toxic-metabolic
- Idiopathic
- Generic
- Autoimmune
- Recurrent and Severe Acute Pancreatitis
- Obstructive Answer: Types of Chronic Pancreatitis
Most common cause of clinically apparent chronic pancreatitis Answer: Alcoholism
Most frequent cause of chronic pancreatitis in children Answer: Cystic fibrosis
Chronic Pancreatitis - Symptoms Answer: - Chronic pain
- Steatorrhea
- DM
- Weight loss
- Fatigue
Chronic Pancreatitis - Diagnosis Answer: - Imaging: EUS, MRI, CT, ERCP, Ultrasound
- Labs: Secretin Test, Fecal Elastase - less then 200 ug/g of stool, Serum Trypsin - less
then 20 mg/dl
- Fecal Elastase - less then 200 ug/g of stool
4
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| TRUSTED TEST SOLUTIONS!
Common causes of Acute Pancreatitis Answer: - Gallstones
- Alcohol
- Hypertriglyceridemia
- Endoscopic retrograde cholangiopancreatography (ERCP)
- Trauma
- Postoperative
- Drugs
- Sphincter of Oddi dysfunction
Acute Pancreatitis that is mild and self-limited Answer: Interstitial pancreatitis
Acute Pancreatitis in which there is pancreatic necrosis and may correlate with the
severity of clinical manifestations Answer: Necrotizing pancreatitis
- Gallstones
- Alcohol
- Hypertriglyceridemia
- Endoscopic retrograde cholangiopancreatography (ERCP)
- Trauma
- Postoperative
- Drugs
- Sphincter of Oddi dysfunction
Common causes of? Answer: Acute Pancreatitis
Phases of acute Pancreatitis Answer: - Initial Phase: Intra pancreatic digestive enzyme
activation and acinar cell injury
- Second phase: activation, chemo attraction, sequestration of neutrophils -> intra
pancreatic inflammation
1
APPHIA - Crafted with Care and Precision for Academic Excellence.
,- Third phase: due to the effects on the distant organs of activated proteolytic enzymes
and cytokines -> proteolysis, edema, interstitial hemorrhage, vascular damage, coag
necrosis
Acute Pancreatitis clinical manifestations Answer: Abdominal pain located in the
epigastrium and periumbilical region and often radiates to the back as well as to the
chest, flanks, and lower abdomen
- More intense when the patient is supine
What causes abdominal pain located in the epigastrium and periumbilical region and
often radiates to the back as well as to the chest, flanks, and lower abdomen
- More intense when the patient is supine Answer: Acute Pancreatitis
Gray Turner's sign Answer: Bruising of the flanks
- Seen in acute pancreatitis
Bruising of the flanks Answer: Gray Turner's sign
- Seen in acute pancreatitis
Acute pancreatitis physical findings Answer: - Gray Turner's sign - Bruising of the flanks
- Cullen's sign - Bruising and edema around umbilicus
Gray Turner's sign and Cullen's sign are seen in? Answer: Acute pancreatitis
Cullen's sign Answer: Bruising and edema around umbilicus
- Seen in acute pancreatitis
Bruising and edema around umbilicus Answer: Cullen's sign
- Seen in acute pancreatitis
Acute Pancreatitis lab findings Answer: - Elevated Amylase and Lipase
- Leukocytosis
- Hyperglycemia
- Hypocalcemia
- Hyperbilirubinemia
Elevated Amylase and Lipase Answer: Acute Pancreatitis l
- Elevated Amylase and Lipase
- Leukocytosis
2
APPHIA - Crafted with Care and Precision for Academic Excellence.
,- Hyperglycemia
- Hypocalcemia
- Hyperbilirubinemia
Lab findings of? Answer: Acute Pancreatitis
Markers of acute pancreatitis severity Answer: - Hemo concentration (Hct >44%)
- Age >60 years
- Blood urea nitrogen (BUN) >25 mg/dl
What hemo concentration is considered severe in acute pancreatitis Answer: Hct >44%
What BUN concentration is considered severe in acute pancreatitis Answer: >25 mg/dl
Acute Pancreatitis diagnosis Answer: - Typical abdominal pain
- Threefold or greater elevation in serum amylase and/or lipase level,
- Confirmatory findings on cross-sectional
abdominal imaging
Mild Acute Pancreatitis treatment Answer: Suupportive care
- clear liquid diet or low-fat solid diet
Severe Acute Pancreatitis treatment Answer: - Vigorous fluid resuscitation
- Measurement of hematocrit and BUN every 12 hours
- Enteral nutrition to prevent infectious complications
- Nasogastric delivery and nasojejunal delivery
Chronic Pancreatitis Answer: Irreversible damage to the pancreas as distinct from the
reversible changes noted in acute pancreatitis
Histologic abnormalities in chronic pancreatitis Answer: - chronic inflammation
- fibrosis
- progressive destruction of both exocrine and eventually
endocrine tissue
Pancreatitis with:
- chronic inflammation
3
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, - fibrosis
- progressive destruction of both exocrine and eventually
endocrine tissue Answer: Chronic pancreatitis
Types of Chronic Pancreatitis Answer: - Toxic-metabolic
- Idiopathic
- Generic
- Autoimmune
- Recurrent and Severe Acute Pancreatitis
- Obstructive
(TIGAR-O)
- Toxic-metabolic
- Idiopathic
- Generic
- Autoimmune
- Recurrent and Severe Acute Pancreatitis
- Obstructive Answer: Types of Chronic Pancreatitis
Most common cause of clinically apparent chronic pancreatitis Answer: Alcoholism
Most frequent cause of chronic pancreatitis in children Answer: Cystic fibrosis
Chronic Pancreatitis - Symptoms Answer: - Chronic pain
- Steatorrhea
- DM
- Weight loss
- Fatigue
Chronic Pancreatitis - Diagnosis Answer: - Imaging: EUS, MRI, CT, ERCP, Ultrasound
- Labs: Secretin Test, Fecal Elastase - less then 200 ug/g of stool, Serum Trypsin - less
then 20 mg/dl
- Fecal Elastase - less then 200 ug/g of stool
4
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