Apex ANS Mobile Flashcards (LATEST )
QUESTIONS AND VERIFIED ANSWERS | 100%
CORRECT | GRADE A+
Terms in this set (53) Exam Questions Verified Answers
1. What are the 4 classifications of receptors? -Ion channel
-G-protein coupled receptor
-Enzyme linked receptor
-Intracellular receptor
2. What is signal transduction? the process by which a cell
converts an extracellular signal
into an intracellular response
3. Describe the general architecture of the G 1st messenger - extracellular
protein second messenger system signal
Receptor- responds to signal
G protein- turns off or on effector
Effector- activates or inhibits the
second messenger
Second messenger- primary
intracellular signal
, Enzymatic cascade
Cellular response- physiologic
change
4. What second messenger system is associated Alpha 1- GQ- Phospholipase C-
with the alpha-1 receptor? What other IP3 + CA+ DAG
receptors share a similar pathway? Other receptors- histamine 1,
muscarinic 1, muscarinic 3,
muscarinic 5, vasopressin 1
5. What second messenger system is associated A2- GI- stops adenylate cyclase
with the alpha-2 receptor? What other and conversion of ATP to cAMP
receptors share a similar pathway? Other receptors- Muscarinic 2,
dopamine 2 (pre-synaptic)
6. What second messenger system is associated B1 or B2- GS- Stimulates
with the beta-1 and beta-2 receptor? What adenylate cyclase, allows
other receptors share a similar pathway? conversion of ATP to cAMP
Other receptors-Histamine 2,
vasopressin 2 (renal), dopamine 1
(Post-synaptic)
7. Describe the autonomic innervation of the B1 = increased contractility, HR
heart and CV
M2 = decreased contractility, HR
and CV
SNS- cardiac accelerator fibers
QUESTIONS AND VERIFIED ANSWERS | 100%
CORRECT | GRADE A+
Terms in this set (53) Exam Questions Verified Answers
1. What are the 4 classifications of receptors? -Ion channel
-G-protein coupled receptor
-Enzyme linked receptor
-Intracellular receptor
2. What is signal transduction? the process by which a cell
converts an extracellular signal
into an intracellular response
3. Describe the general architecture of the G 1st messenger - extracellular
protein second messenger system signal
Receptor- responds to signal
G protein- turns off or on effector
Effector- activates or inhibits the
second messenger
Second messenger- primary
intracellular signal
, Enzymatic cascade
Cellular response- physiologic
change
4. What second messenger system is associated Alpha 1- GQ- Phospholipase C-
with the alpha-1 receptor? What other IP3 + CA+ DAG
receptors share a similar pathway? Other receptors- histamine 1,
muscarinic 1, muscarinic 3,
muscarinic 5, vasopressin 1
5. What second messenger system is associated A2- GI- stops adenylate cyclase
with the alpha-2 receptor? What other and conversion of ATP to cAMP
receptors share a similar pathway? Other receptors- Muscarinic 2,
dopamine 2 (pre-synaptic)
6. What second messenger system is associated B1 or B2- GS- Stimulates
with the beta-1 and beta-2 receptor? What adenylate cyclase, allows
other receptors share a similar pathway? conversion of ATP to cAMP
Other receptors-Histamine 2,
vasopressin 2 (renal), dopamine 1
(Post-synaptic)
7. Describe the autonomic innervation of the B1 = increased contractility, HR
heart and CV
M2 = decreased contractility, HR
and CV
SNS- cardiac accelerator fibers
