Michigan Nurse Anesthetist Specialty
Exam Practice Questions And Correct
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Rationale 2026 Q&A| Instant Download
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1. Which of the following is the most appropriate induction agent for a
patient with hemodynamic instability?
A. Propofol
B. Etomidate
C. Thiopental
D. Midazolam
Etomidate is preferred in hemodynamically unstable patients because it
maintains cardiovascular stability better than other induction agents.
2. During rapid-sequence intubation, which medication is used to
provide neuromuscular blockade with the fastest onset?
A. Rocuronium
B. Vecuronium
C. Succinylcholine
D. Pancuronium
Succinylcholine has the fastest onset among commonly used
neuromuscular blockers, making it ideal for rapid-sequence intubation.
3. Which of the following opioids has the shortest duration of action
suitable for intraoperative analgesia?
, A. Morphine
B. Fentanyl
C. Remifentanil
D. Hydromorphone
Remifentanil is metabolized by plasma esterases, giving it an ultra-short
duration ideal for titratable intraoperative analgesia.
4. A patient presents with sudden bronchospasm after induction of
anesthesia. What is the first-line treatment?
A. Epinephrine IV
B. Albuterol via inhalation
C. Hydrocortisone IV
D. Diphenhydramine IV
Inhaled β2-agonists like albuterol are first-line therapy for acute
bronchospasm during anesthesia.
5. Which local anesthetic has the highest risk of systemic toxicity if
inadvertently injected intravascularly?
A. Lidocaine
B. Ropivacaine
C. Bupivacaine
D. Bupivacaine (particularly racemic form)
Bupivacaine is cardiotoxic at high plasma levels, especially the racemic
mixture, and carries the highest risk of systemic toxicity.
6. In a patient with malignant hyperthermia, which agent should be
administered immediately?
A. Propofol
B. Succinylcholine
C. Dantrolene
D. Midazolam
Dantrolene is the specific antidote for malignant hyperthermia, reducing
calcium release from the sarcoplasmic reticulum.
, 7. Which inhalational anesthetic provides the greatest degree of
myocardial depression?
A. Nitrous oxide
B. Sevoflurane
C. Halothane
D. Desflurane
Halothane depresses myocardial contractility more than modern agents
and can precipitate arrhythmias in susceptible patients.
8. Which monitoring parameter is most sensitive for detecting early
hypoventilation under general anesthesia?
A. Pulse oximetry
B. ECG
C. Capnography
D. Noninvasive blood pressure
Capnography provides immediate feedback on ventilation and is more
sensitive than oxygen saturation in detecting hypoventilation.
9. During spinal anesthesia, which physiologic change is most likely?
A. Tachycardia
B. Hypotension due to sympathetic blockade
C. Hypertension
D. Bradycardia only without hypotension
Sympathetic blockade from spinal anesthesia causes vasodilation and
hypotension, which is the most common physiologic effect.
10. Which of the following patients is at greatest risk for
postoperative respiratory depression when receiving opioids?
A. Young healthy adult
B. Elderly patient with obstructive sleep apnea
C. Middle-aged patient with asthma
D. Healthy pediatric patient
Exam Practice Questions And Correct
Answers (Verified Answers) Plus
Rationale 2026 Q&A| Instant Download
1. Which of the following is the most appropriate induction agent for a
patient with hemodynamic instability?
A. Propofol
B. Etomidate
C. Thiopental
D. Midazolam
Etomidate is preferred in hemodynamically unstable patients because it
maintains cardiovascular stability better than other induction agents.
2. During rapid-sequence intubation, which medication is used to
provide neuromuscular blockade with the fastest onset?
A. Rocuronium
B. Vecuronium
C. Succinylcholine
D. Pancuronium
Succinylcholine has the fastest onset among commonly used
neuromuscular blockers, making it ideal for rapid-sequence intubation.
3. Which of the following opioids has the shortest duration of action
suitable for intraoperative analgesia?
, A. Morphine
B. Fentanyl
C. Remifentanil
D. Hydromorphone
Remifentanil is metabolized by plasma esterases, giving it an ultra-short
duration ideal for titratable intraoperative analgesia.
4. A patient presents with sudden bronchospasm after induction of
anesthesia. What is the first-line treatment?
A. Epinephrine IV
B. Albuterol via inhalation
C. Hydrocortisone IV
D. Diphenhydramine IV
Inhaled β2-agonists like albuterol are first-line therapy for acute
bronchospasm during anesthesia.
5. Which local anesthetic has the highest risk of systemic toxicity if
inadvertently injected intravascularly?
A. Lidocaine
B. Ropivacaine
C. Bupivacaine
D. Bupivacaine (particularly racemic form)
Bupivacaine is cardiotoxic at high plasma levels, especially the racemic
mixture, and carries the highest risk of systemic toxicity.
6. In a patient with malignant hyperthermia, which agent should be
administered immediately?
A. Propofol
B. Succinylcholine
C. Dantrolene
D. Midazolam
Dantrolene is the specific antidote for malignant hyperthermia, reducing
calcium release from the sarcoplasmic reticulum.
, 7. Which inhalational anesthetic provides the greatest degree of
myocardial depression?
A. Nitrous oxide
B. Sevoflurane
C. Halothane
D. Desflurane
Halothane depresses myocardial contractility more than modern agents
and can precipitate arrhythmias in susceptible patients.
8. Which monitoring parameter is most sensitive for detecting early
hypoventilation under general anesthesia?
A. Pulse oximetry
B. ECG
C. Capnography
D. Noninvasive blood pressure
Capnography provides immediate feedback on ventilation and is more
sensitive than oxygen saturation in detecting hypoventilation.
9. During spinal anesthesia, which physiologic change is most likely?
A. Tachycardia
B. Hypotension due to sympathetic blockade
C. Hypertension
D. Bradycardia only without hypotension
Sympathetic blockade from spinal anesthesia causes vasodilation and
hypotension, which is the most common physiologic effect.
10. Which of the following patients is at greatest risk for
postoperative respiratory depression when receiving opioids?
A. Young healthy adult
B. Elderly patient with obstructive sleep apnea
C. Middle-aged patient with asthma
D. Healthy pediatric patient
