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CONTEMPORARY CLINICAL IMMUNOLOGY AND SEROLOGY FINAL EXAM QUESTIONS AND CORRECT ANSWERS VERIFIED A+ 2026

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A phagocytic cell is a(n) -correct answersmacrophage The first cell at the site of an infection is a(n) -correct answersneutrophil A pattern recognition receptor is (are) -correct answerstoll-like receptor A secondary lymphoid organ is (are) -correct answersSALT The innate immune system used -correct answersPRR to recognize PAMP The phagocytic cell that does not arrive first at the site of a chronic infection is the -correct answersmacrophage The two different cells needed to produce a monoclonal antibody are -correct answersA myeloma cell that does not survive in the media used after fusion and a spleen cell from an immunized animal Immunoglobulin diversity is produced in three stages. Which stage(s) is (are) accomplished after interaction with antigen -correct answersClonal deletion of self-reactive B cells and somatic mutation and affinity maturation

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Institution
Contemporary Clinical Immunology
Module
Contemporary Clinical Immunology

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A phagocy c cell is a(n) -correct answersmacrophage



The first cell at the site of an infec on is a(n) -correct answersneutrophil



A pa ern recogni on receptor is (are) -correct answerstoll-like receptor



A secondary lymphoid organ is (are) -correct answersSALT



The innate immune system used -correct answersPRR to recognize PAMP



The phagocy c cell that does not arrive first at the site of a chronic infec on is the -correct
answersmacrophage



The two different cells needed to produce a monoclonal an body are -correct answersA
myeloma cell that does not survive in the media used a er fusion and a spleen cell from an
immunized animal



Immunoglobulin diversity is produced in three stages. Which stage(s) is (are) accomplished a er
interac on with an gen -correct answersClonal dele on of self-reac ve B cells and soma c
muta on and affinity matura on

, If a par cular IgG molecule and IgM molecule have the same affinity, which would have a higher
avidity -correct answersIgM



The area which soma c muta on occurs and increased affinity of an body develops is the -
correct answerslymph node



In the original experiment which determined the structure of immunoglobulins, it was broken
into heavy and light chains using -correct answersurea and mercaptoethanol



To get an body diversity to the level that is needed, -correct answersrecombina on events
occur, slight changes in the junc onal region during recombina on can occur, and soma c
muta on can occur



The an body molecule that has 10 binding sites but because of steric hinderance o en binds
only five an gen molecules is -correct answersIgM



The paratope that is seen as an an gen is called an -correct answersidotype



A spleen cell and a myeloma cell are used to produce a monoclonal an body. How do they help
produce a monoclonal an body -correct answersThe myeloma cell and the spleen cell are fused
to become one cell, a hybridoma



Immunoglobulin diversity and T cell receptor diversity both involve random recombina onal
events to create diversity -correct answersA er an gen exposure, B cells have soma c
muta onal events to improve affinity, but T cells do not



Monoclonal an bodies are produced by cells that are the hybrids of -correct answersspleen
cells and myeloma cells

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Institution
Contemporary Clinical Immunology
Module
Contemporary Clinical Immunology

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