CMMB 527; ADVANCED HEALTH ASSESSMENT
IMMUNOLOGY STUDY TEST EXAM QUESTIONS AND
CORRECT ANSWERS 2026
What part of the immune system is germ-line encoded? -correct answersPa ern recogni on
receptors
- bind to pathogen-associated molecular pa erns (PAMPs)
What is involved in the humoral and cell-mediated response -correct answersB (humoral) and T
(cell-mediated) respnose
How are B and T cell receptors made -correct answersRandomly generated by DNA
rearrangements
Dysfunc ons of immunity categories -correct answersOverly ac ve or misdirected immune
responses
- allergies/asthma
- autoimmune
- immounodeficiency
--> primary (gene c) loss of func on
--> secondary (acquired) loss of func on
Monocytes -correct answers- innate
- 2-4% of WBC
- migrate into ssues and differen ate into macrophages
,- live days to weeks
- differen ate into macrophage (repair/remodel, destroy pathogens) and dendri c cells (present
an gens, no granules)
Neutrophils -correct answers- 65% of WBC
- important in early stages of inflamma on (first 4 hours)
- short lived: 10 hours in circula on, 1-2 days in ssue
- degranula on of potent granules (proteases, an -microbial agents)
- release cytokines, NET
- phagocytosis
Basophil/mast cell -correct answers- heavily granulted: proteases, histamine
- lifespan: hours to days in blood (basophils) or months (mast)
- important mediators of hypersensi vity and allergic responses through produc on of
histamine and cytokines
- Mast cell only mature once in ssue (unlike basophils)
Eosinophils -correct answers- Contain many granules: histamine and proteases
- 4-5% or 10-20% during parasi c infec on
- involved in allergy/hypersensi vity reac ons
- 8-12 day lifespan
- degranulate and release toxic proteins
- bind an body material through Fc receptor
- an body dependent cell mediated cytotoxicity (ADCC)
Megkaryocytes -correct answersPlatelets: most numerous cell in the blood and smallest
- made from megakaryocyte cell bits
, - circulate 7019 days
- no nucleus, rich in granules
- release growth factors and cytokines
- main func on: prevent bleeding via clo ng
T or F: lymphoid cells are phagocy c -correct answersF, they are non-phagocy c cells
Natural killer cell -correct answers- very aggressive innate immune cell: a ack tumour and some
virus-infected cells
- lifespan: weeks
- receptors can bind to an bodies (ADCC)
- ac vate release of granules that can destroy other cells through binding of ac va ng receptors
Characteris cs of primary lymphoid organs -correct answers- bone marrow and thymus
- site of lymphocyte development
- an gen independent
Characteris cs of secondary (peripheral) lymphoid organs -correct answers- lymph nodes,
spleen, MALT, and other loosely organized areas
- collec on site for mature lymphocytes and Ag
- Ag driven ac va on, differen a on and clonal expansion of specific lymphocytes into effector
cells
What connects primary and secondary lymphoid organs? -correct answersblood and lympha c
circulatory systems
Movement of lymph -correct answersOrder:
IMMUNOLOGY STUDY TEST EXAM QUESTIONS AND
CORRECT ANSWERS 2026
What part of the immune system is germ-line encoded? -correct answersPa ern recogni on
receptors
- bind to pathogen-associated molecular pa erns (PAMPs)
What is involved in the humoral and cell-mediated response -correct answersB (humoral) and T
(cell-mediated) respnose
How are B and T cell receptors made -correct answersRandomly generated by DNA
rearrangements
Dysfunc ons of immunity categories -correct answersOverly ac ve or misdirected immune
responses
- allergies/asthma
- autoimmune
- immounodeficiency
--> primary (gene c) loss of func on
--> secondary (acquired) loss of func on
Monocytes -correct answers- innate
- 2-4% of WBC
- migrate into ssues and differen ate into macrophages
,- live days to weeks
- differen ate into macrophage (repair/remodel, destroy pathogens) and dendri c cells (present
an gens, no granules)
Neutrophils -correct answers- 65% of WBC
- important in early stages of inflamma on (first 4 hours)
- short lived: 10 hours in circula on, 1-2 days in ssue
- degranula on of potent granules (proteases, an -microbial agents)
- release cytokines, NET
- phagocytosis
Basophil/mast cell -correct answers- heavily granulted: proteases, histamine
- lifespan: hours to days in blood (basophils) or months (mast)
- important mediators of hypersensi vity and allergic responses through produc on of
histamine and cytokines
- Mast cell only mature once in ssue (unlike basophils)
Eosinophils -correct answers- Contain many granules: histamine and proteases
- 4-5% or 10-20% during parasi c infec on
- involved in allergy/hypersensi vity reac ons
- 8-12 day lifespan
- degranulate and release toxic proteins
- bind an body material through Fc receptor
- an body dependent cell mediated cytotoxicity (ADCC)
Megkaryocytes -correct answersPlatelets: most numerous cell in the blood and smallest
- made from megakaryocyte cell bits
, - circulate 7019 days
- no nucleus, rich in granules
- release growth factors and cytokines
- main func on: prevent bleeding via clo ng
T or F: lymphoid cells are phagocy c -correct answersF, they are non-phagocy c cells
Natural killer cell -correct answers- very aggressive innate immune cell: a ack tumour and some
virus-infected cells
- lifespan: weeks
- receptors can bind to an bodies (ADCC)
- ac vate release of granules that can destroy other cells through binding of ac va ng receptors
Characteris cs of primary lymphoid organs -correct answers- bone marrow and thymus
- site of lymphocyte development
- an gen independent
Characteris cs of secondary (peripheral) lymphoid organs -correct answers- lymph nodes,
spleen, MALT, and other loosely organized areas
- collec on site for mature lymphocytes and Ag
- Ag driven ac va on, differen a on and clonal expansion of specific lymphocytes into effector
cells
What connects primary and secondary lymphoid organs? -correct answersblood and lympha c
circulatory systems
Movement of lymph -correct answersOrder:
