Asthma -correct answersChronic disease due to bronchoconstric on and an excessive
inflammatory response in the bronchioles
What are 5 s/s of asthma -correct answerscoughing
wheezing
shortness of breath
rapid breathing
chest ghtness
Pathophysiology of asthma (5) -correct answers-airway inflamma on, bronchial hyper-reac vity
and smooth muscle spasm
-excess mucus produc on and accumula on
-hypertrophy of bronchial smooth muscle
-airflow obstruc on
-decreased alveolar ven la on
Bronchioles -correct answerssmaller passageways that originate from the bronchi that become
the alveoli
3 layers of the bronchioles -correct answersinnermost layer
middle layer - lamina propria
outermost layer
,lamina propria -correct answersthe middle layer of the bronchioles
structure of the lamina propria -correct answersembedded with connec ve ssue cells and
immune cells
purpose of the lamina propria -correct answerswhite blood cells are present to help protect the
airways
How does the lamina propria effect the lungs in regards to asthma -correct answersthe WBCs
protec ve feature goes into overdrive causing an inflammatory response that damages host
ssue
What does the innermost layer of the bronchioles contain -correct answerscolumnar epithelial
ells and mucus producing goblet cells
What does the outermost layer of the bronchioles contain -correct answerssmooth muscle cells
what does the outermost layer of the bronchioles do -correct answerscontrol the airways ability
to constrict and dilate
alveolar hyperinfla on -correct answersWhen air is unable to move out of the alveolar like it
should due to bronchial walls collapsing around possible mucus plug thus trapping air inside
how does hyperinfla on occur? -correct answersthe ongoing inflammatory process of asthma
produces mucus and pus plug that the bronchial walls collapse around
Effect of hyperinfla on of the alveolar -correct answers-expanded thorax and hypercapnia
(reten on of CO2)
, - respiratory acidosis
What are two an cholinergic drugs used for asthma -correct answers otropium and
ipratropium
What do an cholinergics do in the lungs? -correct answersThese drugs block the effects of the
parasympathe c nervous system
- increasing bronchodila on
MOA of an cholinergic drugs for asthma -correct answersthe parasympathe c system is
s mulated by the vagal nerve to release acetylcholine which binds to the cholinergic receptors
of the respiratory tract to cause bronchial constric on = decreased airflow
- blocking the cholinergic receptors prevents acetylcholine binding preven ng the bronchial
constric on
bronchi s -correct answersinflamma on of the bronchial tubes
3 characteris cs of bronchi s -correct answersbronchial inflamma on
hypersecre on of mucus
chronic produc ve cough for at least 3 consecu ve months for at least 2 successive years
Perfusion -correct answersThe supply of oxygen to and removal of wastes from the cells and
ssues of the body as a result of the flow of blood through the capillaries.
results of chronic bronchi s/ low perfusion -correct answerscyanosis
right to le shun ng
chronic hypoxemia
inflammatory response in the bronchioles
What are 5 s/s of asthma -correct answerscoughing
wheezing
shortness of breath
rapid breathing
chest ghtness
Pathophysiology of asthma (5) -correct answers-airway inflamma on, bronchial hyper-reac vity
and smooth muscle spasm
-excess mucus produc on and accumula on
-hypertrophy of bronchial smooth muscle
-airflow obstruc on
-decreased alveolar ven la on
Bronchioles -correct answerssmaller passageways that originate from the bronchi that become
the alveoli
3 layers of the bronchioles -correct answersinnermost layer
middle layer - lamina propria
outermost layer
,lamina propria -correct answersthe middle layer of the bronchioles
structure of the lamina propria -correct answersembedded with connec ve ssue cells and
immune cells
purpose of the lamina propria -correct answerswhite blood cells are present to help protect the
airways
How does the lamina propria effect the lungs in regards to asthma -correct answersthe WBCs
protec ve feature goes into overdrive causing an inflammatory response that damages host
ssue
What does the innermost layer of the bronchioles contain -correct answerscolumnar epithelial
ells and mucus producing goblet cells
What does the outermost layer of the bronchioles contain -correct answerssmooth muscle cells
what does the outermost layer of the bronchioles do -correct answerscontrol the airways ability
to constrict and dilate
alveolar hyperinfla on -correct answersWhen air is unable to move out of the alveolar like it
should due to bronchial walls collapsing around possible mucus plug thus trapping air inside
how does hyperinfla on occur? -correct answersthe ongoing inflammatory process of asthma
produces mucus and pus plug that the bronchial walls collapse around
Effect of hyperinfla on of the alveolar -correct answers-expanded thorax and hypercapnia
(reten on of CO2)
, - respiratory acidosis
What are two an cholinergic drugs used for asthma -correct answers otropium and
ipratropium
What do an cholinergics do in the lungs? -correct answersThese drugs block the effects of the
parasympathe c nervous system
- increasing bronchodila on
MOA of an cholinergic drugs for asthma -correct answersthe parasympathe c system is
s mulated by the vagal nerve to release acetylcholine which binds to the cholinergic receptors
of the respiratory tract to cause bronchial constric on = decreased airflow
- blocking the cholinergic receptors prevents acetylcholine binding preven ng the bronchial
constric on
bronchi s -correct answersinflamma on of the bronchial tubes
3 characteris cs of bronchi s -correct answersbronchial inflamma on
hypersecre on of mucus
chronic produc ve cough for at least 3 consecu ve months for at least 2 successive years
Perfusion -correct answersThe supply of oxygen to and removal of wastes from the cells and
ssues of the body as a result of the flow of blood through the capillaries.
results of chronic bronchi s/ low perfusion -correct answerscyanosis
right to le shun ng
chronic hypoxemia
