Sarhan Comprehensive Exam 2026|
High-Yield Pharmacology Prep for
Advanced Practice Nursing
A 35-year-old man, recently immigrated from Guatemala, presents with fatigue,
lethargy, and mouth sores. The NP suspects scurvy and prepares which
medication? -ANSWER- Ascorbic Acid.
First line drug of choice for CAP in a previously healthy adult would include: -
ANSWER- Azithromycin (a macrolide)
One month after starting phenytoin for seizures, a 28-year-old male presents
with complaints of fever, rash, and swollen lymph nodes. The NP suspects which
syndrome? -ANSWER- Phenytoin hypersensitivity reaction
A patient with previous compliant levels of carbamazepine levels now presents
with subtherapeutic blood levels. The NP suspects? -ANSWER- Carbamazepine
auto induces metabolism so you go through the drug a lot quicker so it is an expected
lab finding.
The NP educates the patient regarding the Black Box warning on carbamazepine
by advising the patient to report signs and symptoms indicative of: -ANSWER-
Skin Reaction (Steven Johnson Syndrome and TEN (Toxic Epidermal necrolysis))
Carbamazepine monitoring should include all of the following except: -
ANSWER- Monthly Glucose
A patient taking Lamictal presents with fever, cough, and swollen lymph nodes,
what does the NP suspect? -ANSWER- Lamictal hypersensitivity reaction.
A young women taking Lamictal for seizures presents to the office requesting
birth control. She has decided she wants daily oral contraceptives. The NP
educates the patient regarding the fact: -ANSWER- Lamictal doses will need to be
increased while taking oral contraceptives.
Tricyclic antidepressants should be avoided in? -ANSWER- Heart failure patients.
When educating patients regarding antidepressants, the NP should include: -
ANSWER- It may take 2-3 weeks for medications to take effect.
, After ordering IM Haldol for the patient, the NP knows to assess for EPS using
which tool? -ANSWER- AIMS (abnormal involuntary movement scale) test
Prior to administering albuterol for an acute asthma attack while on digoxin, the
NP understands that: -ANSWER- Digoxin dose will need to be increased.
The NP opts NOT to give a beta agonist to which patient? -ANSWER- History of
pheochromocytoma.
The NP educates which patient population regarding salmeterol's Black Box
Warning? -ANSWER- African Americans
The NP believes the patient needs additional education regarding long-acting
beta agonist's Black Box warning when the patient verbalizes? -ANSWER- "I
take this medication in case of an asthma attack."
A 72-year-old presents to the clinic with the cc of "I can't pee". Which history
does the NP suspect may be causing this symptoms? -ANSWER- Taking Benadryl
for seasonal allergies. Benadryl can cause urinary retention.
A patient recently diagnosed with pneumonia, is also found to have osteoporosis,
anemia, and vitamin B12 deficiency. The NP suspects which TX is causing the
patient's issues? -ANSWER- Long Term PPI therapy
When determining appropriate antimicrobial tx, the NP utilizes which tool to
assess local resistance patterns? -ANSWER- Antibiogram
After receiving Flagyl for a diverticulitis flare up, the patient calls the clinic
complaining of nausea, vomiting, and ABD pain. The NP focuses on which part
of the SOAP note to rule out a disulfiram reaction? -ANSWER- Social history
Which pt should receive fluoroquinolone therapy for CAP (community-acquired
pneumonia) diagnosis? -ANSWER- A 44-year-old female with DM.
Sulfonamides should be avoided in patients with a G6PD deficiency (x-linked in
African American) due to risk of: -ANSWER- hemolytic anemia
A 16YO presents to the clinic for tx of her acne. The NP prescribes which
medication? -ANSWER- Combination antibiotic and topical.
A teenager comes to the clinic with complaint of headache. The NP suspects
minocycline may be causing the symptoms due to its risk of: -ANSWER-
Pseudotumor cerbri (increased intracranial pressure)
Which tx is appropriate for a patient with new onset of cluster headaches? -
ANSWER- 100% oxygen for 15-30 minutes
When should the NP expect to see clinical improvement after starting antibiotic
therapy for a pneumonia patient? -ANSWER- 2-3 days