(Solutions Manual & Presentation Slides) A First
Course in Systems Biology (2nd Edition, 2017)
Systems Biology - answer-The Study of how molecules interact and come together to give rise
to.
Experimentally - answer-development of microarrays to measure the levels of thousands of
mRNAs simultaneously allowed us to see how many components in a cell change in response to
stimuli
Computationally - answer-simulations showed how interaction between components give rise
to functional capabilities (in this case switching behavior) that the individual components do not
have.
Chemotaxis - answer-The characteristic movement or orientation of an organism or cell along a
chemical concentration gradient either toward or away from the chemical stimulus
Experiments and Computation - answer-together showed how certain system behavior such as
adaptation in
bacterial chemotaxis is robust ...that is insensitive to variation of concentrations of protein
components in the network
Physiology has provided description of... - answer-functions at tissue/organ level, most often
from a phenomenological perspective... a very useful and essential starting point
Genome - answer-A set of chromosomes
1
Course in Systems Biology (2nd Edition, 2017)
Systems Biology - answer-The Study of how molecules interact and come together to give rise
to.
Experimentally - answer-development of microarrays to measure the levels of thousands of
mRNAs simultaneously allowed us to see how many components in a cell change in response to
stimuli
Computationally - answer-simulations showed how interaction between components give rise
to functional capabilities (in this case switching behavior) that the individual components do not
have.
Chemotaxis - answer-The characteristic movement or orientation of an organism or cell along a
chemical concentration gradient either toward or away from the chemical stimulus
Experiments and Computation - answer-together showed how certain system behavior such as
adaptation in
bacterial chemotaxis is robust ...that is insensitive to variation of concentrations of protein
components in the network
Physiology has provided description of... - answer-functions at tissue/organ level, most often
from a phenomenological perspective... a very useful and essential starting point
Genome - answer-A set of chromosomes
1
