Nurse Practitioner Certification Exam
2026 – Complete Questions & Answers
with Rationales
1. lesion that develops on previously unaltered skin - answer-primary lesion
2. a region in an organ or tissue that has suffered damage thru injury or
disease - answer-lesion
3. lesion that either changes impression over time or occurs when a primary
lesion is scratched it may be infected - answer-secondary lesion
4. circumscribed flat area; different color and texture from surrounding tissue,
<1cm
5. ex.) ephelides (freckles), petechia, flat nevi (moles) - answer-macule
6. a large macule; >1cm
7. ex.) mongolian spot, Cafe, au lair spot - answer-patch
8. Small solid elevated lesion; <1cm
9. ex.) bug bite, elevated nevus (mole) or verruca (wart) - answer-papule
10.elevation of skin; >1cm; example psoriasis lesion - answer-plaque
11.a visible accumulation of purulent fluid under skin; <1cm; examples acne
and impetigo - answer-pustule
,12.a circumscribed elevation of skin contains "SEROUS FLUID: <1cm; examples,
herpes simples, varicella, shingles - answer-vesicle
13.solid mass of skin, is elevated or palpated >1cm; often extends deeper into
dermis: examples xanthoma and fibroma - answer-nodule
14.blister, circumscribed elevation containing fluid >1cm , extends only into
epidermis, examples burns, superficial blister, contact dermatitis - answer-
bulla
15.elevated white or pink compressible papule or plaque, a red, axon-
mediated flare often surround it, commonly associated with allergic
reaction, examples PPD test and mosquito bites - answer-wheal
16.any closed cavity or sac; contains fluid or semisolid material, normal or
abnormal epithelium. example sebaceous cyst - answer-cyst
17.a localized collection of purulent fluid in a cavity formed by disintegration
or necrosis of tissues >1cm - answer-Abscess
18."MASS: > few cm in diameter; firm or soft; benign or malignant - answer-
tumor
19.circular, begins in center and spreads to periphery - answer-configuration:
annular
, 20.lesions run together - answer-configuration: confluent
21.lesion cluster - answer-configuration: grouped
22.twisted, coiled, spiral and snake like - answer-configuration: gyrate
23.scratch, streak, line stripe - answer-configuration: linear
24.annular lesions merge - answer-configuration: polycyclic
25.individual and distinct lesions that remain separate - answer-configuration:
solitary or discrete
26.resembles iris of eye; lesion with concentric rings of color - answer-
configuration: target (iris)
27.linear arrangement along nerve route - answer-configuration: zosteriform
28.open are called black heads (openings capped with a blackened skin
debris); and closed are called white head (obstructed) - answer-comedones
29.can be comedones, pustules, papules (pimples and zits), cysts, nodules and
scaring - answer-acne
2026 – Complete Questions & Answers
with Rationales
1. lesion that develops on previously unaltered skin - answer-primary lesion
2. a region in an organ or tissue that has suffered damage thru injury or
disease - answer-lesion
3. lesion that either changes impression over time or occurs when a primary
lesion is scratched it may be infected - answer-secondary lesion
4. circumscribed flat area; different color and texture from surrounding tissue,
<1cm
5. ex.) ephelides (freckles), petechia, flat nevi (moles) - answer-macule
6. a large macule; >1cm
7. ex.) mongolian spot, Cafe, au lair spot - answer-patch
8. Small solid elevated lesion; <1cm
9. ex.) bug bite, elevated nevus (mole) or verruca (wart) - answer-papule
10.elevation of skin; >1cm; example psoriasis lesion - answer-plaque
11.a visible accumulation of purulent fluid under skin; <1cm; examples acne
and impetigo - answer-pustule
,12.a circumscribed elevation of skin contains "SEROUS FLUID: <1cm; examples,
herpes simples, varicella, shingles - answer-vesicle
13.solid mass of skin, is elevated or palpated >1cm; often extends deeper into
dermis: examples xanthoma and fibroma - answer-nodule
14.blister, circumscribed elevation containing fluid >1cm , extends only into
epidermis, examples burns, superficial blister, contact dermatitis - answer-
bulla
15.elevated white or pink compressible papule or plaque, a red, axon-
mediated flare often surround it, commonly associated with allergic
reaction, examples PPD test and mosquito bites - answer-wheal
16.any closed cavity or sac; contains fluid or semisolid material, normal or
abnormal epithelium. example sebaceous cyst - answer-cyst
17.a localized collection of purulent fluid in a cavity formed by disintegration
or necrosis of tissues >1cm - answer-Abscess
18."MASS: > few cm in diameter; firm or soft; benign or malignant - answer-
tumor
19.circular, begins in center and spreads to periphery - answer-configuration:
annular
, 20.lesions run together - answer-configuration: confluent
21.lesion cluster - answer-configuration: grouped
22.twisted, coiled, spiral and snake like - answer-configuration: gyrate
23.scratch, streak, line stripe - answer-configuration: linear
24.annular lesions merge - answer-configuration: polycyclic
25.individual and distinct lesions that remain separate - answer-configuration:
solitary or discrete
26.resembles iris of eye; lesion with concentric rings of color - answer-
configuration: target (iris)
27.linear arrangement along nerve route - answer-configuration: zosteriform
28.open are called black heads (openings capped with a blackened skin
debris); and closed are called white head (obstructed) - answer-comedones
29.can be comedones, pustules, papules (pimples and zits), cysts, nodules and
scaring - answer-acne
