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NU 327 Pathophysiology
Exam 2 – Part 2 Questions
& Answers 2026/2027
Page 1
Guidehttps://www.stuvia.com/dashboard!@_)#*)(@$)($@*($@)($@*_ NU 327 Pathophysiology Exam 2 – Part 2 Questions & Answers 2026_2027.pdf
,NU 327 Patho Exam 2 Part 2 2026-02-25
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Terms (100)
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Components of adaptive immunity
Antigens - substances that evoke the immune response
Antibodies/Immunoglobulins - substances secreted in response to the antigen
Lymphocytes (B cells and T cells) - cells that recognize and respond to the antigen to attack and
remove it
Macrophages - present the antigen to the lymphocytes
cell-mediated adaptive immunity
composed of T cells that develop from stem cells in the bone marrow and move to the thymus gland
to mature; differentiate by protein marking into T4 cells with CD4+ (helper cells that conduct immune
response) and T8 cells with CD8+ (cytotoxic cells that attack foreign invaders), also include cytokines
Page 2 NU 327 Patho Exam 2 Part 2.pdf
,NU 327 Patho Exam 2 Part 2 2026-02-25
Major Histocompatibility Complex (MHC)
proteins that mark cells to allow them to allow the immune system to recognize self v. non-self; play
a role in transplant rejection and transfusion reactions, also called Human Leukocyte Antigens
(HLAs)
humoral adaptive immunity
composed B cells; born of stem cells the remain in the bone marrow to mature; function to produce
antibodies (IgG, IgM, IgA, IgD, IgE)
primary response to an antigen
first exposure to an antigen that stimulates the development of antibodies- ex: vaccines
secondary response to an antigen
occurs when a person is subsequently exposed to an antigen after developing antibodies
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, NU 327 Patho Exam 2 Part 2 2026-02-25
What is the role of IgG?
most abundant immunoglobulin in the blood; second responder to antigens- bacteria, toxins, viruses
What is the role of IgM?
first responder to antigens; elevated levels indicate recent infections
What is the role of IgA?
found in mucosal secretions of the mucous membranes (sweat, saliva, tears, nasal, bronchial and
digestive tract secretions)
What is the role of IgD?
binds to basophils and mast cells; stimulate B cells
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