Nurs 328 exam 1 week 3 part 1 UPDATED ACTUAL
Questions and CORRECT Answers
What is selective toxicity? The ability of a drug to injure a target cell without
injuring other cells in contact with the target.
Name one example of selective Disruption of the bacterial cell wall.
toxicity.
How are antimicrobials classified by Broad spectrum vs. Narrow spectrum, Gram
susceptible organism? negative vs. Gram positive, Aerobic vs. Anaerobic.
What is the difference between Bactericidal is lethal to the target, while
bactericidal and bacteriostatic? bacteriostatic slows growth and relies on host
defenses to kill the bacteria.
What does 'match the drug to the The process of selecting an antibiotic based on the
bug' refer to? identity of the infecting organism.
What are host factors that influence Age, pregnancy, previous drug use, immune system
antibiotic selection? status, allergies, and site of infection.
Why is routine use of combination It can lead to additive, potentiative, or antagonistic
antibiotics not recommended? effects; the goal is monotherapy.
What is antibiotic prophylaxis used Preventing infections in situations like surgery,
for? bacterial endocarditis, and neutropenia.
, Define antibiotic resistance. When an organism that was once sensitive to an
antibiotic becomes less susceptible or loses
sensitivity entirely.
How can bacteria resist a drug? By reducing drug concentration at the site of
action, drug inactivation, or alteration of drug
target molecules.
What is spontaneous mutation in A gradual increase in resistance that confers
antibiotic resistance? resistance to only one drug.
What is conjugation in the context of The transfer of DNA from one bacterium to
antibiotic resistance? another, causing multiple drug resistance.
Why do broad-spectrum antibiotics They affect a wider range of bacteria, increasing
promote resistance more than the chance of resistant strains emerging.
narrow-spectrum antibiotics?
What is antimicrobial stewardship? Efforts to prevent infections, diagnose and treat
effectively, use antibiotics judiciously, and prevent
patient-to-patient transmission.
What should nurses assess for Clinical response (reduction of fever, resolution of
success of antibiotic therapy? symptoms) and laboratory response (serum drug
levels, post-treatment culture).
What client education should be Medication details, importance of completing the
provided regarding antibiotics? course, and potential side effects.
What role does infection control It is essential to prevent the spread of infections
play in antibiotic therapy? and ensure effective treatment.
Questions and CORRECT Answers
What is selective toxicity? The ability of a drug to injure a target cell without
injuring other cells in contact with the target.
Name one example of selective Disruption of the bacterial cell wall.
toxicity.
How are antimicrobials classified by Broad spectrum vs. Narrow spectrum, Gram
susceptible organism? negative vs. Gram positive, Aerobic vs. Anaerobic.
What is the difference between Bactericidal is lethal to the target, while
bactericidal and bacteriostatic? bacteriostatic slows growth and relies on host
defenses to kill the bacteria.
What does 'match the drug to the The process of selecting an antibiotic based on the
bug' refer to? identity of the infecting organism.
What are host factors that influence Age, pregnancy, previous drug use, immune system
antibiotic selection? status, allergies, and site of infection.
Why is routine use of combination It can lead to additive, potentiative, or antagonistic
antibiotics not recommended? effects; the goal is monotherapy.
What is antibiotic prophylaxis used Preventing infections in situations like surgery,
for? bacterial endocarditis, and neutropenia.
, Define antibiotic resistance. When an organism that was once sensitive to an
antibiotic becomes less susceptible or loses
sensitivity entirely.
How can bacteria resist a drug? By reducing drug concentration at the site of
action, drug inactivation, or alteration of drug
target molecules.
What is spontaneous mutation in A gradual increase in resistance that confers
antibiotic resistance? resistance to only one drug.
What is conjugation in the context of The transfer of DNA from one bacterium to
antibiotic resistance? another, causing multiple drug resistance.
Why do broad-spectrum antibiotics They affect a wider range of bacteria, increasing
promote resistance more than the chance of resistant strains emerging.
narrow-spectrum antibiotics?
What is antimicrobial stewardship? Efforts to prevent infections, diagnose and treat
effectively, use antibiotics judiciously, and prevent
patient-to-patient transmission.
What should nurses assess for Clinical response (reduction of fever, resolution of
success of antibiotic therapy? symptoms) and laboratory response (serum drug
levels, post-treatment culture).
What client education should be Medication details, importance of completing the
provided regarding antibiotics? course, and potential side effects.
What role does infection control It is essential to prevent the spread of infections
play in antibiotic therapy? and ensure effective treatment.
