PRACTITIONER (AGPCNP-C) BOARD CERTIFICATION
EXAMINATION – AANP COMPREHENSIVE PRACTICE
ASSESSMENT - LATEST PRACTICE QUESTIONS AND 100%
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Exam Overview:
This comprehensive 150-question multiple-choice assessment mirrors the structure and rigor of the
AGPCNP-C (AANP) certification examination. It evaluates clinical knowledge, advanced assessment
skills, diagnostic reasoning, pharmacologic and non-pharmacologic management, health promotion,
disease prevention, professional role, ethics, policy, and evidence-based practice.
Content Distribution (150 Questions):
Health Promotion & Disease Prevention – 20 questions
Assessment & Diagnosis – 35 questions
Clinical Management (Adult & Geriatric across body systems) – 70 questions
Professional Role, Policy, Ethics & Research – 25 questions
1. A 52-year-old male presents for annual examination. He has a 30-pack-year
smoking history and quit 5 years ago. Which screening is recommended?
A. Annual chest X-ray
B. Low-dose CT starting at age 60
C. Annual low-dose CT scan of the chest
D. Sputum cytology annually
Rationale: Annual low-dose CT is recommended for adults aged 50–80 with ≥20
pack-year history who currently smoke or quit within 15 years.
2. A 68-year-old female asks about pneumococcal vaccination. She previously
received PPSV23 at age 60. What is appropriate now?
A. No further vaccination
B. Repeat PPSV23 today
, C. Administer PCV20
D. Administer PCV13 only
Rationale: Current guidelines recommend PCV20 alone or PCV15 followed by
PPSV23 in adults ≥65.
3. A 74-year-old male with weight loss, anemia, and change in bowel habits
most urgently requires:
A. Fecal occult blood testing
B. Repeat CBC
C. Abdominal ultrasound
D. Colonoscopy
Rationale: Alarm symptoms suggest colorectal malignancy requiring diagnostic
colonoscopy.
4. A 45-year-old woman with BMI 33 kg/m² should be screened for:
A. Ovarian cancer
B. Lung cancer
C. Type 2 diabetes mellitus
D. Thyroid cancer
Rationale: Adults aged 35–70 with overweight/obesity should be screened for
diabetes.
5. A 70-year-old with unsteady gait reports two falls this year. First step?
A. Prescribe walker
B. Perform multifactorial fall risk assessment
, C. Order brain MRI
D. Refer to neurology
Rationale: Geriatric fall evaluation includes medication review, vision, gait,
strength, and home safety.
6. A patient with BP 138/86 mmHg on two visits is classified as:
A. Normal
B. Elevated
C. Stage 1 hypertension
D. Stage 2 hypertension
Rationale: Stage 1 HTN is 130–139 systolic or 80–89 diastolic.
7. A 66-year-old male with new atrial fibrillation and CHA₂DS₂-VASc score of
3 should receive:
A. Aspirin
B. No therapy
C. Oral anticoagulation
D. Clopidogrel
Rationale: Score ≥2 (men) warrants anticoagulation.
8. First-line therapy for uncomplicated hypertension in non-Black adult
without CKD:
A. Beta blocker
B. Thiazide diuretic
C. Loop diuretic
D. Clonidine
, Rationale: Thiazides are first-line agents.
9. A diabetic patient with albuminuria should receive:
A. Beta blocker
B. Calcium channel blocker
C. ACE inhibitor
D. Nitrate
Rationale: ACE inhibitors slow diabetic nephropathy progression.
10.A 72-year-old presents with confusion, UTI suspected. Most reliable
diagnostic indicator?
A. Foul-smelling urine
B. Confusion alone
C. Urinalysis with pyuria and bacteriuria plus symptoms
D. Positive urine culture alone
Rationale: Asymptomatic bacteriuria is common in elderly; symptoms plus lab
evidence required.
11.A 59-year-old male with chest pain radiating to jaw requires first:
A. Chest X-ray
B. ECG within 10 minutes
C. Troponin after 6 hours
D. Stress test
Rationale: Immediate ECG for suspected ACS.
12.Most sensitive test for diagnosing PE in stable patient:
A. Chest X-ray