1
ONCOLOGY NURSING EXAM – CHEMOTHERAPY, RADIATION
& SYMPTOM CONTROL 2026-27 JUST RELEASED VERSION
Exam Structure
• Total Questions: 100
• Format: Multiple Choice (Single Best Answer)
• Level: University / RN–BSN / Post-RN
• Time: 120–150 minutes
Introduction
This exam evaluates the nurse’s knowledge and clinical judgment in oncology care, focusing on:
• Safe administration of chemotherapy and radiation therapy
• Management of common treatment side effects
• Recognition and intervention for oncology-related complications
• Symptom management to optimize patient safety and quality of life
Questions reflect evidence-based practice and require critical thinking, prioritization, and safe
nursing decision-making.
Question Format
• Four options (A–D)
• One best correct answer
• Clinical-scenario or case-based when appropriate
Answer & Rationale Format
• Correct Answer: Letter
• Rationale: Concise explanation referencing oncology standards, symptom management,
and safety principles
,2
SECTION I: CHEMOTHERAPY SAFETY & ADMINISTRATION (Q1–
20)
Q1.
The nurse’s highest priority before administering chemotherapy
is:
A. Preparing IV fluids
B. Checking the patient’s allergies and lab results
C. Hanging the chemotherapy bag
D. Starting the IV
Correct Answer: B
Rationale: Confirming patient identity, allergies, and lab results
ensures safe administration and prevents adverse events.
Q2.
Which personal protective equipment (PPE) is mandatory when
handling chemotherapy drugs?
A. Gloves only
B. Gown, double gloves, and eye protection
C. Surgical mask only
D. Shoe covers
,3
Correct Answer: B
Rationale: Gown, gloves, and eye protection prevent
occupational exposure to cytotoxic drugs.
Q3.
Extravasation during chemotherapy occurs when:
A. The drug enters the bloodstream too quickly
B. The drug leaks into surrounding tissue
C. The drug causes nausea
D. The infusion is completed early
Correct Answer: B
Rationale: Cytotoxic drugs can damage surrounding tissues if
the IV infiltrates.
Q4.
Best nursing intervention for chemotherapy extravasation is:
A. Apply warm or cold compress based on drug type
B. Continue infusion
C. Remove IV and ignore
D. Increase infusion rate
Correct Answer: A
Rationale: Immediate application of compresses reduces tissue
damage depending on the drug’s properties.
, 4
Q5.
The most important lab value to check before chemotherapy is:
A. Blood glucose
B. WBC count
C. Sodium
D. Platelet count
Correct Answer: B
Rationale: Low WBC count increases infection risk;
chemotherapy can worsen myelosuppression.
Q6.
A patient receiving cisplatin reports tinnitus. The nurse should:
A. Document only
B. Stop the infusion and notify the provider
C. Continue infusion
D. Administer antiemetic
Correct Answer: B
Rationale: Cisplatin is ototoxic; early recognition prevents
permanent damage.
Q7.
ONCOLOGY NURSING EXAM – CHEMOTHERAPY, RADIATION
& SYMPTOM CONTROL 2026-27 JUST RELEASED VERSION
Exam Structure
• Total Questions: 100
• Format: Multiple Choice (Single Best Answer)
• Level: University / RN–BSN / Post-RN
• Time: 120–150 minutes
Introduction
This exam evaluates the nurse’s knowledge and clinical judgment in oncology care, focusing on:
• Safe administration of chemotherapy and radiation therapy
• Management of common treatment side effects
• Recognition and intervention for oncology-related complications
• Symptom management to optimize patient safety and quality of life
Questions reflect evidence-based practice and require critical thinking, prioritization, and safe
nursing decision-making.
Question Format
• Four options (A–D)
• One best correct answer
• Clinical-scenario or case-based when appropriate
Answer & Rationale Format
• Correct Answer: Letter
• Rationale: Concise explanation referencing oncology standards, symptom management,
and safety principles
,2
SECTION I: CHEMOTHERAPY SAFETY & ADMINISTRATION (Q1–
20)
Q1.
The nurse’s highest priority before administering chemotherapy
is:
A. Preparing IV fluids
B. Checking the patient’s allergies and lab results
C. Hanging the chemotherapy bag
D. Starting the IV
Correct Answer: B
Rationale: Confirming patient identity, allergies, and lab results
ensures safe administration and prevents adverse events.
Q2.
Which personal protective equipment (PPE) is mandatory when
handling chemotherapy drugs?
A. Gloves only
B. Gown, double gloves, and eye protection
C. Surgical mask only
D. Shoe covers
,3
Correct Answer: B
Rationale: Gown, gloves, and eye protection prevent
occupational exposure to cytotoxic drugs.
Q3.
Extravasation during chemotherapy occurs when:
A. The drug enters the bloodstream too quickly
B. The drug leaks into surrounding tissue
C. The drug causes nausea
D. The infusion is completed early
Correct Answer: B
Rationale: Cytotoxic drugs can damage surrounding tissues if
the IV infiltrates.
Q4.
Best nursing intervention for chemotherapy extravasation is:
A. Apply warm or cold compress based on drug type
B. Continue infusion
C. Remove IV and ignore
D. Increase infusion rate
Correct Answer: A
Rationale: Immediate application of compresses reduces tissue
damage depending on the drug’s properties.
, 4
Q5.
The most important lab value to check before chemotherapy is:
A. Blood glucose
B. WBC count
C. Sodium
D. Platelet count
Correct Answer: B
Rationale: Low WBC count increases infection risk;
chemotherapy can worsen myelosuppression.
Q6.
A patient receiving cisplatin reports tinnitus. The nurse should:
A. Document only
B. Stop the infusion and notify the provider
C. Continue infusion
D. Administer antiemetic
Correct Answer: B
Rationale: Cisplatin is ototoxic; early recognition prevents
permanent damage.
Q7.
