1
ISOLATION & PPE NURSING EXAM –
TRANSMISSION-BASED PRECAUTIONS 2026-27
JUST RELEASED VERSION
Exam Structure
• Total Questions: 100
• Format: Multiple Choice (Single Best Answer)
• Level: University / RN–BSN / Post-RN
• Time: 120–150 minutes
Introduction
This exam evaluates the nurse’s knowledge and application of infection prevention and control
measures, emphasizing transmission-based precautions. Topics include:
• Contact, droplet, and airborne precautions – indications, implementation, and monitoring
• Personal protective equipment (PPE) – selection, donning, doffing, and disposal
• Isolation protocols – patient placement, room setup, and environmental cleaning
• Outbreak management – identification, reporting, and containment strategies
• Patient and family education – reducing transmission risk in healthcare and home settings
The exam uses scenario-based questions to test critical thinking, adherence to CDC/AORN guidelines,
and proper use of isolation measures in various clinical situations.
Question & Answer Format
• Four options (A–D)
• One correct answer per question
• Each question includes a rationale referencing infection control standards
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SECTION I: TRANSMISSION-BASED PRECAUTIONS & BASIC PPE
(Q1–30)
Q1.
A patient is diagnosed with Clostridioides difficile (C. diff)
infection. Which isolation precaution is required?
A. Contact precautions with gloves and gown
B. Airborne precautions only
C. Droplet precautions only
D. Standard precautions only
Correct Answer: A
Rationale: C. diff is spread via contact with contaminated
surfaces or patient; contact precautions prevent transmission.
Q2.
Patient has influenza. What isolation is appropriate?
A. Droplet precautions: mask within 3 feet of patient
B. Airborne precautions only
C. Contact precautions only
D. No precautions
,3
Correct Answer: A
Rationale: Influenza spreads via respiratory droplets; surgical
mask prevents transmission.
Q3.
Patient has pulmonary tuberculosis. Which precautions should
the nurse implement?
A. Airborne precautions with N95 respirator and negative
pressure room
B. Droplet precautions only
C. Contact precautions only
D. Standard precautions only
Correct Answer: A
Rationale: TB is airborne; strict isolation and proper PPE
prevent spread.
Q4.
When donning PPE, which order is correct?
A. Gown → Mask/Respirator → Goggles/Face shield → Gloves
B. Gloves → Gown → Mask → Goggles
C. Mask → Gloves → Gown → Goggles
D. Gown → Gloves → Mask → Goggles
, 4
Correct Answer: A
Rationale: Proper sequence prevents contamination during PPE
application.
Q5.
Best practice when removing PPE to prevent self-
contamination:
A. Remove gloves first, then goggles, gown, mask last
B. Remove mask first
C. Remove gown last, gloves first
D. Remove gloves last
Correct Answer: A
Rationale: Gloves are most contaminated; removing them first
reduces risk of spreading pathogens.
Q6.
Patient with measles should be placed in:
A. Airborne isolation with negative pressure room
B. Contact isolation only
C. Droplet isolation only
D. Standard precautions only
Correct Answer: A
Rationale: Measles is highly airborne; negative pressure
prevents spread.
ISOLATION & PPE NURSING EXAM –
TRANSMISSION-BASED PRECAUTIONS 2026-27
JUST RELEASED VERSION
Exam Structure
• Total Questions: 100
• Format: Multiple Choice (Single Best Answer)
• Level: University / RN–BSN / Post-RN
• Time: 120–150 minutes
Introduction
This exam evaluates the nurse’s knowledge and application of infection prevention and control
measures, emphasizing transmission-based precautions. Topics include:
• Contact, droplet, and airborne precautions – indications, implementation, and monitoring
• Personal protective equipment (PPE) – selection, donning, doffing, and disposal
• Isolation protocols – patient placement, room setup, and environmental cleaning
• Outbreak management – identification, reporting, and containment strategies
• Patient and family education – reducing transmission risk in healthcare and home settings
The exam uses scenario-based questions to test critical thinking, adherence to CDC/AORN guidelines,
and proper use of isolation measures in various clinical situations.
Question & Answer Format
• Four options (A–D)
• One correct answer per question
• Each question includes a rationale referencing infection control standards
,2
SECTION I: TRANSMISSION-BASED PRECAUTIONS & BASIC PPE
(Q1–30)
Q1.
A patient is diagnosed with Clostridioides difficile (C. diff)
infection. Which isolation precaution is required?
A. Contact precautions with gloves and gown
B. Airborne precautions only
C. Droplet precautions only
D. Standard precautions only
Correct Answer: A
Rationale: C. diff is spread via contact with contaminated
surfaces or patient; contact precautions prevent transmission.
Q2.
Patient has influenza. What isolation is appropriate?
A. Droplet precautions: mask within 3 feet of patient
B. Airborne precautions only
C. Contact precautions only
D. No precautions
,3
Correct Answer: A
Rationale: Influenza spreads via respiratory droplets; surgical
mask prevents transmission.
Q3.
Patient has pulmonary tuberculosis. Which precautions should
the nurse implement?
A. Airborne precautions with N95 respirator and negative
pressure room
B. Droplet precautions only
C. Contact precautions only
D. Standard precautions only
Correct Answer: A
Rationale: TB is airborne; strict isolation and proper PPE
prevent spread.
Q4.
When donning PPE, which order is correct?
A. Gown → Mask/Respirator → Goggles/Face shield → Gloves
B. Gloves → Gown → Mask → Goggles
C. Mask → Gloves → Gown → Goggles
D. Gown → Gloves → Mask → Goggles
, 4
Correct Answer: A
Rationale: Proper sequence prevents contamination during PPE
application.
Q5.
Best practice when removing PPE to prevent self-
contamination:
A. Remove gloves first, then goggles, gown, mask last
B. Remove mask first
C. Remove gown last, gloves first
D. Remove gloves last
Correct Answer: A
Rationale: Gloves are most contaminated; removing them first
reduces risk of spreading pathogens.
Q6.
Patient with measles should be placed in:
A. Airborne isolation with negative pressure room
B. Contact isolation only
C. Droplet isolation only
D. Standard precautions only
Correct Answer: A
Rationale: Measles is highly airborne; negative pressure
prevents spread.
