Ventilation, Alveolar Gas Exchange, Respiratory
Membrane Physiology, Bronchial Tree &
Bronchioles, Surfactant & Type II Pneumocytes,
Compliance & Intrapleural Pressure, Tidal Volume
& Lung Capacities, Dalton’s Law & Partial
Pressures, Oxygen–Hemoglobin Dissociation Curve
& Bohr Effect, Carbon Dioxide Transport & Chloride
Shift, Neural Control (DRG, VRG, Apneustic &
Pneumotaxic Centers), Chemoreceptor &
Baroreceptor Reflexes, Autonomic Bronchodilation
& Bronchoconstriction, Pulmonary Circulation &
ACE, Pleural Dynamics, Respiratory Distress
Syndrome, Pneumothorax, Hypercapnia &
Hypocapnia, Fetal Hemoglobin, SIDS, and
Cardiopulmonary Homeostatic Integration Exam
Questions Verified and Provided with A+ Graded
Rationales Latest Updated 2026
The Respiration System
Cells produce energy for maintenance, growth, defense, & division
- Through mechanisms that us oxygen & produce carbon dioxide
Oxygen
- Obtained from the air by diffusion across delicate exchange surfaces of lungs
- Carried to cells by the cardiovascular system, which also returns carbon dioxide to the lungs
5 Functions of the Respiratory System
1. Provides extensive gas exchange surface area between air and circulating blood
,2. Moves air to and from exchange surfaces of lungs
3. Protects respiratory surfaces from outside environment
4. Produces sounds
5. Participates in olfactory sense
Upper Respiratory System
Above the larynx
Lower Respiratory System
Below the larynx
The Respiratory Tract
- Consist of a conducting portion (conducts air) from the nasal cavity to terminal bronchioles
- Consists of a respiratory portion (filters air)
--> The respiratory bronchioles & alveoli
- Alveoli: air-filled pockets within the lungs where all gas exchange takes place
Respiratory Epithelium
- Alveoli walls are very thin
- Surface area is about 35 times the surface of the body
Respiratory Mucosa
- Lines the conducting portion of the respiratory system
- 2 Layers: epithelial layer & lamina propria
- Lamina propria
--> Underlying layer of areolar tissue that supports the respiratory epithelium
--> In the upper respiratory system, trachea, & bronchi
--> Mucous glands that secrete onto epithelial surface (lubrication)
--> In the conducting portion of lower respiratory system smooth muscle cells that encircle
lumen of bronchioles
, Structure of Respiratory Epithelium
Pseudostratified ciliated columnar epithelium
- Nasal cavity & superior portion of the pharynx
- Superior portion of lower respiratory system
Stratified squamous epithelium
- Inferior portions of the pharynx
Cuboidal epithelium with scattered cilia
- smaller bronchioles
Alveolar Epithelium
- Very delicate, simple squamous epithelium
- Contains scattered & specialized cells
- Lines exchange surfaces
Respiratory System Defense Processes
- Consists of a series of filtration mechanisms
- Removes particles & pathogens
- Mucous cells & mucous glands: produce mucous that bathes exposed surfaces
- Cilia: sweep debris trapped in mucus toward the pharynx
- Filtration in nasal cavity removes large particles
- Alveolar macrophages engulf small particles that reach lungs
Nose
- Air enters the respiratory system
- Through nostrils or external nares into nasal vestibule (passageway)
- Nasal hairs are in nasal vestibule: make up the first particle filtration system