NUR 370 Exam #1 Pharmacology Exam
Questions With Correct Answers
What |are |the |3 |most |important |properties |of |an |ideal |drug? |- |CORRECT |ANSWER✔✔-1) |
Effectiveness
2) |Safety
3) |Selectivity
NOTE: |Other |less |important |properties |include |reversible |action, |predictability, |ease |of |
administration, |freedom |from |drug |interactions, |low |cost, |stability, |etc.
What |3 |things |determines |the |intensity |of |drug |response? |- |CORRECT |ANSWER✔✔-1) |
Administration |route.
2) |Pharmacokinetics |(PK) |- |what |the |body |does |to |the |drug.
3) |Pharmacodynamics |(PD) |- |what |the |drug |does |to |the |body.
What |are |the |4 |basic |processes |of |pharmacokinetics? |- |CORRECT |ANSWER✔✔-1) |Absorption
2) |Distribution
3) |Metabolism
4) |Excretion
TIP: |Think |of |mnemonic |'ADME'.
What |organ(s) |is |the |primary |site |of |drug |metabolism? |- |CORRECT |ANSWER✔✔-The |liver.
, What |organ(s) |is |primarily |responsible |for |drug |excretion? |- |CORRECT |ANSWER✔✔-The |
kidneys.
NOTE: |This |is |not |to |say |there |are |not |other |routes |of |excretion.
What |are |the |3 |ways |for |a |drug |to |cross |a |cell |membrane? |- |CORRECT |ANSWER✔✔-1) |Direct |
penetration |- |drug |must |have |some |degree |of |lipid |solubility.*
2) |Channels |and |pores.
3) |Transport |systems.
NOTE: |Drugs |that |are |highly |polar |are |not |going |to |be |good |at |crossing |membranes. |
*Most |typical |way |of |drugs |crossing |the |cell |membrane.
Define |'bioavailability'. |- |CORRECT |ANSWER✔✔-Bioavailability |is |the |amount |of |drug |reaching |
systemic |circulation |from |site |of |administration.
List |some |of |the |factors |affecting |drug |absorption. |- |CORRECT |ANSWER✔✔-- |Rate |of |
dissolution
- |Surface |area
- |Blood |flow
- |Lipid |solubility
Questions With Correct Answers
What |are |the |3 |most |important |properties |of |an |ideal |drug? |- |CORRECT |ANSWER✔✔-1) |
Effectiveness
2) |Safety
3) |Selectivity
NOTE: |Other |less |important |properties |include |reversible |action, |predictability, |ease |of |
administration, |freedom |from |drug |interactions, |low |cost, |stability, |etc.
What |3 |things |determines |the |intensity |of |drug |response? |- |CORRECT |ANSWER✔✔-1) |
Administration |route.
2) |Pharmacokinetics |(PK) |- |what |the |body |does |to |the |drug.
3) |Pharmacodynamics |(PD) |- |what |the |drug |does |to |the |body.
What |are |the |4 |basic |processes |of |pharmacokinetics? |- |CORRECT |ANSWER✔✔-1) |Absorption
2) |Distribution
3) |Metabolism
4) |Excretion
TIP: |Think |of |mnemonic |'ADME'.
What |organ(s) |is |the |primary |site |of |drug |metabolism? |- |CORRECT |ANSWER✔✔-The |liver.
, What |organ(s) |is |primarily |responsible |for |drug |excretion? |- |CORRECT |ANSWER✔✔-The |
kidneys.
NOTE: |This |is |not |to |say |there |are |not |other |routes |of |excretion.
What |are |the |3 |ways |for |a |drug |to |cross |a |cell |membrane? |- |CORRECT |ANSWER✔✔-1) |Direct |
penetration |- |drug |must |have |some |degree |of |lipid |solubility.*
2) |Channels |and |pores.
3) |Transport |systems.
NOTE: |Drugs |that |are |highly |polar |are |not |going |to |be |good |at |crossing |membranes. |
*Most |typical |way |of |drugs |crossing |the |cell |membrane.
Define |'bioavailability'. |- |CORRECT |ANSWER✔✔-Bioavailability |is |the |amount |of |drug |reaching |
systemic |circulation |from |site |of |administration.
List |some |of |the |factors |affecting |drug |absorption. |- |CORRECT |ANSWER✔✔-- |Rate |of |
dissolution
- |Surface |area
- |Blood |flow
- |Lipid |solubility
