Lehne's Pharmacology for Nursing Care -
Elsevier e-Book on VitalSource, 12th
Edition
by Jacqueline Rosenjack Burchum, DNSc,
FNP-BC, CNE and Laura D. Rosenthal, DNP,
RN, ACNP-BC, FAANP
TEST BANK
Lehne’s Pharmacology for Nursing Care, 12th Edition
Unit I: Introduction – Chapter 1: Orientation to Pharmacology
1.
A nurse is explaining pharmacology to a new nursing student.
Which statement accurately describes pharmacology?
A. The study of herbal supplements only
B. The study of drug effects on living systems
,C. The study of disease pathology
D. The study of medication administration techniques
Correct Answer: B
Rationale: Pharmacology is the study of drugs and their effects
on living systems. It encompasses pharmacokinetics and
pharmacodynamics.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed.,
Chapter 1: Orientation to Pharmacology
2.
Which branch of pharmacology focuses on what the body does
to a drug?
A. Pharmacodynamics
B. Toxicology
C. Pharmacokinetics
D. Therapeutics
Correct Answer: C
Rationale: Pharmacokinetics describes absorption, distribution,
metabolism, and excretion—how the body affects the drug.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed.,
Chapter 1
3.
,Which process determines how quickly a drug reaches systemic
circulation after oral administration?
A. Distribution
B. Absorption
C. Metabolism
D. Excretion
Correct Answer: B
Rationale: Absorption is the movement of a drug from its site of
administration into the bloodstream.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed.,
Chapter 1
4.
A drug that produces the maximum possible therapeutic effect
is described as having high:
A. Potency
B. Efficacy
C. Affinity
D. Selectivity
Correct Answer: B
Rationale: Efficacy refers to the maximum effect a drug can
produce, regardless of dose.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed.,
Chapter 1
, 5.
Which factor most directly influences drug distribution in the
body?
A. Renal clearance
B. Plasma protein binding
C. Hepatic enzyme activity
D. Drug half-life
Correct Answer: B
Rationale: Drugs bound to plasma proteins cannot cross
membranes; only free (unbound) drug is pharmacologically
active.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed.,
Chapter 1
6.
A nurse identifies that an older adult patient has reduced renal
function. Which pharmacokinetic process is most likely
affected?
A. Absorption
B. Distribution
C. Metabolism
D. Excretion
Correct Answer: D
Elsevier e-Book on VitalSource, 12th
Edition
by Jacqueline Rosenjack Burchum, DNSc,
FNP-BC, CNE and Laura D. Rosenthal, DNP,
RN, ACNP-BC, FAANP
TEST BANK
Lehne’s Pharmacology for Nursing Care, 12th Edition
Unit I: Introduction – Chapter 1: Orientation to Pharmacology
1.
A nurse is explaining pharmacology to a new nursing student.
Which statement accurately describes pharmacology?
A. The study of herbal supplements only
B. The study of drug effects on living systems
,C. The study of disease pathology
D. The study of medication administration techniques
Correct Answer: B
Rationale: Pharmacology is the study of drugs and their effects
on living systems. It encompasses pharmacokinetics and
pharmacodynamics.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed.,
Chapter 1: Orientation to Pharmacology
2.
Which branch of pharmacology focuses on what the body does
to a drug?
A. Pharmacodynamics
B. Toxicology
C. Pharmacokinetics
D. Therapeutics
Correct Answer: C
Rationale: Pharmacokinetics describes absorption, distribution,
metabolism, and excretion—how the body affects the drug.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed.,
Chapter 1
3.
,Which process determines how quickly a drug reaches systemic
circulation after oral administration?
A. Distribution
B. Absorption
C. Metabolism
D. Excretion
Correct Answer: B
Rationale: Absorption is the movement of a drug from its site of
administration into the bloodstream.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed.,
Chapter 1
4.
A drug that produces the maximum possible therapeutic effect
is described as having high:
A. Potency
B. Efficacy
C. Affinity
D. Selectivity
Correct Answer: B
Rationale: Efficacy refers to the maximum effect a drug can
produce, regardless of dose.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed.,
Chapter 1
, 5.
Which factor most directly influences drug distribution in the
body?
A. Renal clearance
B. Plasma protein binding
C. Hepatic enzyme activity
D. Drug half-life
Correct Answer: B
Rationale: Drugs bound to plasma proteins cannot cross
membranes; only free (unbound) drug is pharmacologically
active.
Citation: Lehne’s Pharmacology for Nursing Care, 12th ed.,
Chapter 1
6.
A nurse identifies that an older adult patient has reduced renal
function. Which pharmacokinetic process is most likely
affected?
A. Absorption
B. Distribution
C. Metabolism
D. Excretion
Correct Answer: D
